Human CCR10 APC-conjugated Antibody

Catalog #: FAB3478A
7 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB3478A-025
FAB3478A-100

Detection of CCR10 in Human PBMCs by Flow Cytometry.

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All CCR10 Antibodies

Product Details

Citations (7)

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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CCR10 APC-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detect human CCR10. Stains human CCR10-transfected cells but not irrelevant transfectants.

Source

Monoclonal Rat IgG_2A Clone # 314305

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Y3 rat myeloid cell line transfected with human CCR10
Gln8-Asn362
Accession # P46092

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of CCR10 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3e Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB100F) and either (A) Rat Anti-Human CCR10 APC-conjugated Monoclonal Antibody (Catalog # FAB3478A) or (B) Rat IgG_2AAllophycocyanin Isotype Control (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.

Flow Cytometry

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Detection of CCR10 in L1.2 Mouse Cell Line Transfected with Human CCR10 and eGFP by Flow Cytometry. L1.2 mouse pro-B cell line transfected with human CCR10 and eGFP was stained with either (A) Rat IgG_2AAllophycocyanin Isotype Control (Catalog # IC006A) or (B) Rat Anti-Human CCR10 APC-conjugated Monoclonal Antibody (Catalog # FAB3478A). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: CCR10

CCR10 is a G protein-linked seven transmembrane domain protein expressed by T cells and B cell subsets that functions as a receptor for CCL27 and CCL28. CCR10 mediates lymphocyte migration to the skin and mucosa, and its expression is correlated with the metastatic behavior of melanomas.

Entrez Gene IDs

2826 (Human); 12777 (Mouse); 363682 (Rat)

Alternate Names

CC chemokine receptor 10; C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR10; CCR-10; chemokine (C-C motif) receptor 10; G protein-coupled receptor 2; GPR2; GPR2G-protein coupled receptor 2

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human CCR10 APC-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

7 Citations: Showing 1 - 7
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Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19
Authors: Can Liu, Andrew J. Martins, William W. Lau, Nicholas Rachmaninoff, Jinguo Chen, Luisa Imberti et al.
Cell
Immune cell profiles in synovial fluid after anterior cruciate ligament and meniscus injuries
Authors: SY Kim-Wang, AG Holt, AM McGowan, ST Danyluk, AP Goode, BC Lau, AP Toth, JR Wittstein, LE DeFrate, JS Yi, AL McNulty
Arthritis Research & Therapy, 2021-11-04;23(1):280.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS
Authors: T Karnezis, R Farnsworth, NC Harris, SP Williams, C Caesar, DJ Byrne, P Herle, ML Macheda, R Shayan, YF Zhang, S Yazar, SJ Takouridis, C Gerard, S Fox, MG Achen, SA Stacker
Cancer Res., 2019-02-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
A role for CCL28-CCR3 in T-cell homing to the human upper airway mucosa.
Authors: Danilova, E, Skrindo, I, Gran, E, Hales, B J, Smith, W A, Jahnsen, J, Johansen, F E, Jahnsen, F L, Baekkevold, E S
Mucosal Immunol, 2014-06-11;8(1):107-14.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica.
Authors: Chihara, Norio, Aranami, Toshimas, Oki, Shinji, Matsuoka, Takako, Nakamura, Masakazu, Kishida, Hitaru, Yokoyama, Kazumasa, Kuroiwa, Yoshiyuk, Hattori, Nobutaka, Okamoto, Tomoko, Murata, Miho, Toda, Tatsushi, Miyake, Sachiko, Yamamura, Takashi
PLoS ONE, 2013-12-10;8(12):e83036.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab.
Authors: Mei HE, Frolich D, Giesecke C, Loddenkemper C, Reiter K, Schmidt S, Feist E, Daridon C, Tony HP, Radbruch A, Dorner T
Blood, 2010-09-09;116(24):5181-90.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
CCL28 is increased in human Helicobacter pylori-induced gastritis and mediates recruitment of gastric immunoglobulin A-secreting cells.
Authors: Hansson M, Hermansson M, Svensson H, Elfvin A, Hansson LE, Johnsson E, Sjoling A, Quiding-Jarbrink M
Infect. Immun., 2008-04-21;76(7):3304-11.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry