Human Cytosol Nonspecific
Dipeptidase (CNDP2)/CPGL Antibody

Catalog #: MAB3560
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB3560
MAB3560-SP

All Cytosol Nonspecific Dipeptidase (CNDP2)/CPGL Antibodies

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Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Cytosol Nonspecific
Dipeptidase (CNDP2)/CPGL Antibody Summary

Species Reactivity

Human

Specificity

Detects human Cytosol Nonspecific Dipeptidase (CNDP2)/CPGL in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human CNDP1 is observed.

Source

Monoclonal Mouse IgG₁ Clone # 464702

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Cytosol Nonspecific Dipeptidase (CNDP2)/CPGL
Met1-Asp475
Accession # Q96KP4

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human Cytosol Nonspecific Dipeptidase (CNDP2)/CPGL (Catalog # 3560-ZN)

Immunoprecipitation

25 µg/mL

Cell lysates spiked with Recombinant Human Cytosol Nonspecific Dipeptidase (CNDP2)/CPGL (Catalog # 3560-ZN), see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Cytosol Nonspecific Dipeptidase (CNDP2)/CPGL

The human CNDP2 gene encodes cytosol non-specific dipeptidase, a member of the M20 family of metalloproteases (1, 2). Also known as glutamate carboxypeptidase-like protein 1 (CPGL), tissue carnosinase or peptidase A, CNDP2 is ubiquitously expressed throughout human tissues. Unlike CNDP1, CNDP2 has broad substrate specificity for dipeptides with free amino and carboxyl groups. The amino acid sequence of human CNDP2 is 90% and 84% identical to that of dog/mouse/rat and chicken, respectively.

References

Teufel, M. et al. (2003) J. Biol. Chem. 278:6521.
Woessner, J. (2004) in Handbook of Proteolytic Enzymes (ed. Barrett, A.J. et al.) pp.1020, Academic Press, San Diego.

Entrez Gene IDs

55748 (Human)

Alternate Names

CN2; CN2cytosolic non-specific dipeptidase; CNDP dipeptidase 2 (metallopeptidase M20 family); CNDP dipeptidase 2; CNDP2; CPGL; CPGLcytosolic nonspecific dipeptidase; FLJ10830; HsT2298; PEPA; PEPAEC 3.4.13.18; Peptidase AGlutamate carboxypeptidase-like protein 1

Product Datasheets

Product Datasheet

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Related Research Areas

Citation for Human Cytosol Nonspecific
Dipeptidase (CNDP2)/CPGL Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1