Human DGK-iota (NP_004708) VersaClone cDNA

Catalog #: RDC2054 Datasheet / COA / SDS

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RDC2054

Human DGK-iota (NP_004708) VersaClone cDNA

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Human DGK-iota (NP_004708) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: DGK-iota

DGK (Diacylglycerol kinase alpha) proteins are type I members of the eukaryocytic diacylglycerol kinase family of enzymes, possessing EF-hand, C1/Cys-rich zinc finger and catalytic domains. DGK-alpha in IL-2-stimulated T cells translocates to the nucleus, promoting proliferation. TCR stimulation, however, promotes anergy. DGK-alpha also participates in VEGF or HGF-mediated motility in endothelial, epithelial, or cancer cells. DGK-gamma is highly enriched in the retina and cerebellar Purkinje cells, and presence of unactivated protein in the nucleus may regulate the cell cycle.

Long Name

Diacylglycerol Kinase, iota 64kDa

Entrez Gene IDs

9162 (Human); 320127 (Mouse); 688705 (Rat)

Alternate Names

DAG kinase iota; DGKI; DGKiota; DGK-iota; diacylglycerol kinase iota; diacylglycerol kinase, iota; Diglyceride kinase iota; EC 2.7.1.107