Human EAR2/NR2F6 Antibody

Catalog #: PP-N2025-00 Datasheet / COA / SDS

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PP-N2025-00

All EAR2/NR2F6 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human EAR2/NR2F6 Antibody Summary

Species Reactivity

Human

Source

Monoclonal Mouse IgG2a Clone # N2025

Formulation

A liquid formulation in physiologic saline with 0.1% NaN₃.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

Please refer to the PDF datasheet for specifications.

Immunohistochemistry

5-15 µg/mL

Perfusion fixed paraffin-embedded sections of rat salivary gland

Immunoprecipitation

Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: EAR2/NR2F6

EAR2 (COUP TF-gamma, ERBAL2; NR2F6) is a member of the orphan nuclear receptor family. No ligand has been reported. Expression is detected in fetal liver, placenta, heart, muscle, and pancreas. No expression of EAR2 was detected in lung and brain tissue. Interaction of EAR2 with the transcription factor CBFA2 reveals a negative regulator of granulocyte differentiation. Knock out of EAR2 has been shown to affect forebrain clock and nociception in mice. EAR2 has also been shown to suppress transcription of luteinizing hormone receptor (LHR).

Long Name

ErbA-related 2

Entrez Gene IDs

2063 (Human)

Alternate Names

EAR2; EAR-2ERBA-related gene-2; EAR2nuclear receptor subfamily 2 group F member 6; ERBAL2; ERBAL2v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2; NR2F6; nuclear receptor subfamily 2, group F, member 6; V-erbA-related protein 2