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Human ERR beta/NR3A2 Antibody

Catalog #: PP-H6707-00
8 Citations Datasheet / COA / SDS
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PP-H6707-00
Product Details
Citations (8)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human ERR beta/NR3A2 Antibody Summary

Species Reactivity
Human
Source
Monoclonal Mouse IgG2a Clone # H6707
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
Please refer to the PDF datasheet for specifications.
Immunoprecipitation
Please refer to the PDF datasheet for specifications.
Direct ELISA
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ERR beta/NR3B2

Estrogen-related receptor alpha (ERR-alpha, ERR1, ESRL1; NR3B1) is a member of the orphan nuclear receptor family. ERR-alpha is expressed in the liver, kidney, brain, heart, uterus, vagina and cervix. ERR-alpha takes part in the cell cycle and the fatty acid metabolizing of the musculus skeleti. ERR-alpha was shown to interact with ER-alpha. ERR-beta (ERR2; NR3B2) is also expressed in the liver, brain, uterus, vagina, and cervix. ERR-beta has a role in early placental development. ERR-gamma (ESRRG; NR3B3) is expressed in the brain, kidney, testis, lung, adrenal gland, pancreas, placenta and bone marrow. ERR-gamma was shown to be located in the critical region for Usher's syndrome.

Long Name
Estrogen-related Receptor beta
Entrez Gene IDs
2103 (Human)
Alternate Names
ERR beta; ERR2; ESRL2; ESRRB; estrogen-related receptor beta; NR3B2

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Citations for Human ERR beta/NR3A2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

8 Citations: Showing 1 - 8
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  1. Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRb2) splice variant in breast cancer
    Authors: Heckler MM, Zeleke TZ, Divekar SD et al.
    Oncotarget
  2. Esrrb Regulates Specific Feed-Forward Loops to Transit From Pluripotency Into Early Stages of Differentiation
    Authors: Amin R. Mazloom, Huilei Xu, Jaume Reig-Palou, Ana Vasileva, Angel-Carlos Román, Sonia Mulero-Navarro et al.
    Frontiers in Cell and Developmental Biology
  3. BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion
    Authors: V Perez-Garc, G Lea, P Lopez-Jime, H Okkenhaug, GJ Burton, A Moffett, MY Turco, M Hemberger
    Elife, 2021-06-25;10(0):.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: IHC, Western Blot
  4. The orphan nuclear receptor estrogen-related receptor beta (ERR beta ) in triple-negative breast cancer
    Authors: Aileen I. Fernandez, Xue Geng, Krysta Chaldekas, Brent Harris, Anju Duttargi, V. Layne Berry et al.
    Breast Cancer Research and Treatment
  5. ERR beta splice variants differentially regulate cell cycle progression
    Authors: Mary Mazzotta Heckler, Rebecca B Riggins
    Cell Cycle
  6. Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming.
    Authors: Percharde M, Lavial F, Ng J, Kumar V, Tomaz R, Martin N, Yeo J, Gil J, Prabhakar S, Ng H, Parker M, Azuara V
    Genes Dev, 2012-09-26;26(20):2286-98.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP, Western Blot
  7. Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression.
    Authors: van den Berg DL, Zhang W, Yates A, Engelen E, Takacs K, Bezstarosti K, Demmers J, Chambers I, Poot RA
    Mol. Cell. Biol., 2008-07-28;28(19):5986-95.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP, Immunoprecipitation
  8. Orphan nuclear receptor estrogen-related receptor-beta suppresses in vitro and in vivo growth of prostate cancer cells via p21(WAF1/CIP1) induction and as a potential therapeutic target in prostate cancer.
    Authors: Yu S, Wong YC, Wang XH, Ling MT, Ng CF, Chen S, Chan FL
    Oncogene, 2007-12-10;27(23):3313-28.
    Species: Human
    Sample Types: Cell Lysates, Whole Tissue
    Applications: ChIP, IHC-P, Western Blot

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