Home / ERR beta/NR3B2 / Human ERR beta/NR3B2 Antibody

Human ERR beta/NR3B2 Antibody

Catalog #: PP-H6705-00
27 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
PP-H6705-00
Detection of Mouse ERR beta/NR3B2 by Immunocytochemistry/Immunofluorescence
1 Image
Product Details
Citations (27)
FAQs
Supplemental Products
Reviews
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human ERR beta/NR3B2 Antibody Summary

Species Reactivity
Human
Source
Monoclonal Mouse IgG2a Clone # H6705
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
Please refer to the PDF datasheet for specifications.
Immunohistochemistry
5-15 µg/mL
Perfusion fixed paraffin-embedded sections of rat kidney
Immunoprecipitation
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunocytochemistry/ Immunofluorescence Detection of Mouse ERR beta/NR3B2 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse ERR beta/NR3B2 by Immunocytochemistry/Immunofluorescence Immediate firing motoneurons, but not delayed firing motoneurons, express ERR beta.(A) Examples of Err beta. staining (red) in neurobiotin (green) filled motoneurons. The arrowhead in the first row points to the nucleus (Err beta −positive) of the recorded motoneuron. The asterisk in the second row indicates that the nucleus of the recorded motoneuron was Err beta −negative. (B) Plot of the AHP relaxation time constants against the rheobases for labelled motoneurons. All immediate firing motoneurons were Err beta −positive whereas all delayed firing motoneurons were Err beta −negative. Arrowheads point to the motoneurons illustrated in A.DOI:https://dx.doi.org/10.7554/eLife.04046.008 Image collected and cropped by CiteAb from the following publication (https://elifesciences.org/articles/04046), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ERR beta/NR3B2

Estrogen-related receptor alpha (ERR-alpha, ERR1, ESRL1; NR3B1) is a member of the orphan nuclear receptor family. ERR-alpha is expressed in the liver, kidney, brain, heart, uterus, vagina and cervix. ERR-alpha takes part in the cell cycle and the fatty acid metabolizing of the musculus skeleti. ERR-alpha was shown to interact with ER-alpha. ERR-beta (ERR2; NR3B2) is also expressed in the liver, brain, uterus, vagina, and cervix. ERR-beta has a role in early placental development. ERR-gamma (ESRRG; NR3B3) is expressed in the brain, kidney, testis, lung, adrenal gland, pancreas, placenta and bone marrow. ERR-gamma was shown to be located in the critical region for Usher's syndrome.

Long Name
Estrogen-related Receptor beta
Entrez Gene IDs
2103 (Human)
Alternate Names
ERR beta; ERR2; ESRL2; ESRRB; estrogen-related receptor beta; NR3B2

Product Datasheets

You must select a language.

x
Product Datasheet
COA
SDS

Citations for Human ERR beta/NR3B2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

27 Citations: Showing 1 - 10
Filter your results:

Filter by:

  1. Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRb2) splice variant in breast cancer
    Authors: Heckler MM, Zeleke TZ, Divekar SD et al.
    Oncotarget
  2. ESRRB inhibits the TGF-? signaling pathway to drive cell proliferation in cervical cancer
    Authors: Li, QS;Zheng, PS;
    Cancer research
    Species: Human
    Sample Types: Cell Lysates, Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot, ChIP
  3. Mitotic bookmarking by SWI/SNF subunits
    Authors: Zhu, Z;Chen, X;Guo, A;Manzano, T;Walsh, PJ;Wills, KM;Halliburton, R;Radko-Juettner, S;Carter, RD;Partridge, JF;Green, DR;Zhang, J;Roberts, CWM;
    Nature
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay, ICC
  4. ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers
    Authors: R Yelagandul, K Stecher, M Novatchkov, L Michetti, G Michlits, J Wang, P Hofbauer, G Vainorius, C Pribitzer, L Isbel, S Mendjan, D Schübeler, U Elling, J Brennecke, O Bell
    Nature Cell Biology, 2023-01-05;0(0):.
    Species: Mouse
    Sample Types: Chromatin
    Applications: ChIP
  5. ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control
    Authors: MN Khan, P Cherukuri, F Negro, A Rajput, P Fabrowski, V Bansal, C Lancelin, TI Lee, Y Bian, WP Mayer, T Akay, D Müller, S Bonn, D Farina, T Marquardt
    PloS Biology, 2022-12-21;20(12):e3001923.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  6. Esrrb is a cell-cycle-dependent associated factor balancing pluripotency and XEN differentiation
    Authors: Sapir Herchcovici Levy, Sharon Feldman Cohen, Lee Arnon, Shlomtzion Lahav, Muhammad Awawdy, Adi Alajem et al.
    Stem Cell Reports
  7. CDX2 downregulation in mouse mural trophectoderm during peri‐implantation is heteronomous, dependent on the YAP‐TEAD pathway and controlled by estrogen‐induced factors
    Authors: Daisuke Suzuki, Keitaro Okura, Seina Nagakura, Hidehiko Ogawa
    Reproductive Medicine and Biology
  8. N6-methyladenosine (m 6 A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells
    Authors: Kang-Xuan Jin, Rujuan Zuo, Konstantinos Anastassiadis, Arne Klungland, Carsten Marr, Adam Filipczyk
    Proceedings of the National Academy of Sciences
  9. Principles of signaling pathway modulation for enhancing human naive pluripotency induction
    Authors: J Bayerl, M Ayyash, T Shani, YS Manor, O Gafni, R Massarwa, Y Kalma, A Aguilera-C, M Zerbib, H Amir, D Sheban, S Geula, N Mor, L Weinberger, S Naveh Tass, V Krupalnik, B Oldak, N Livnat, S Tarazi, S Tawil, E Wildschutz, S Ashouokhi, L Lasman, V Rotter, S Hanna, D Ben-Yosef, N Novershter, S Viukov, JH Hanna
    Cell Stem Cell, 2021-04-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  10. Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
    Authors: R Fan, YS Kim, J Wu, R Chen, D Zeuschner, K Mildner, K Adachi, G Wu, S Galatidou, J Li, HR Schöler, SA Leidel, I Bedzhov
    Nat Commun, 2020-10-30;11(1):5499.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  11. Context-dependent functional compensation between Ythdf m6A reader proteins
    Authors: Lior Lasman, Vladislav Krupalnik, Sergey Viukov, Nofar Mor, Alejandro Aguilera-Castrejon, Dan Schneir et al.
    Genes & Development
  12. Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling
    Authors: Aurélia Huyghe, Giacomo Furlan, Duygu Ozmadenci, Christina Galonska, Jocelyn Charlton, Xavier Gaume et al.
    Nature Cell Biology
  13. The orphan nuclear receptor estrogen-related receptor beta (ERR beta ) in triple-negative breast cancer
    Authors: Aileen I. Fernandez, Xue Geng, Krysta Chaldekas, Brent Harris, Anju Duttargi, V. Layne Berry et al.
    Breast Cancer Research and Treatment
  14. Distinct Molecular Trajectories Converge to Induce Naive Pluripotency
    Authors: Hannah T. Stuart, Giuliano G. Stirparo, Tim Lohoff, Lawrence E. Bates, Masaki Kinoshita, Chee Y. Lim et al.
    Cell Stem Cell
  15. MTCH2-mediated mitochondrial fusion drives exit from na�ve pluripotency in embryonic stem cells
    Authors: A Bahat, A Goldman, Y Zaltsman, DH Khan, C Halperin, E Amzallag, V Krupalnik, M Mullokando, A Silberman, A Erez, AD Schimmer, JH Hanna, A Gross
    Nat Commun, 2018-12-03;9(1):5132.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  16. Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate
    Authors: JL Sardina, S Collombet, TV Tian, A Gómez, B Di Stefano, C Berenguer, J Brumbaugh, R Stadhouder, C Segura-Mor, M Gut, IG Gut, S Heath, S Aranda, L Di Croce, K Hochedling, D Thieffry, T Graf
    Cell Stem Cell, 2018-09-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Immunoprecipitation
  17. One-step generation of conditional and reversible gene knockouts
    Authors: Amanda Andersson-Rolf, Roxana C. Mustata, Alessandra Merenda, Jihoon Kim, Sajith Perera, Tiago Grego et al.
    Nature Methods
  18. Departure from optimal O2 level for mouse trophoblast stem cell proliferation and potency leads to most rapid AMPK activation
    Authors: Daniel A Rappolee
    J. Reprod. Dev., 2016-11-18;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  19. Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen related receptor beta
    Authors: Yuan Lu, Jilong Li, Jianlin Cheng, Dennis B. Lubahn
    BMC Molecular Biology
  20. Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells
    Authors: Yuan Lu, Jilong Li, Jianlin Cheng, Dennis B. Lubahn
    BMC Molecular Biology
  21. ERR beta splice variants differentially regulate cell cycle progression
    Authors: Mary Mazzotta Heckler, Rebecca B Riggins
    Cell Cycle
  22. Deconstructing transcriptional heterogeneity in pluripotent stem cells.
    Authors: Kumar, Roshan M, Cahan, Patrick, Shalek, Alex K, Satija, Rahul, DaleyKeyser, A Jay, Li, Hu, Zhang, Jin, Pardee, Keith, Gennert, David, Trombetta, John J, Ferrante, Thomas C, Regev, Aviv, Daley, George Q, Collins, James J
    Nature, 2014-12-04;516(7529):56-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  23. Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis
    Authors: Félix Leroy, Boris Lamotte d'Incamps, Rebecca D Imhoff-Manuel, Daniel Zytnicki
    eLife
  24. A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages
    Authors: Aliaksandra Radzisheuskaya, Gloryn Le Bin Le Bin Chia, Rodrigo L. dos Santos, Thorold W. Theunissen, L. Filipe C. Castro, Jennifer Nichols et al.
    Nature Cell Biology
  25. Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming.
    Authors: Percharde M, Lavial F, Ng J, Kumar V, Tomaz R, Martin N, Yeo J, Gil J, Prabhakar S, Ng H, Parker M, Azuara V
    Genes Dev, 2012-09-26;26(20):2286-98.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  26. Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression.
    Authors: van den Berg DL, Zhang W, Yates A, Engelen E, Takacs K, Bezstarosti K, Demmers J, Chambers I, Poot RA
    Mol. Cell. Biol., 2008-07-28;28(19):5986-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  27. A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
    Authors: Garland W, Comet I, Wu M et al.
    Cell Rep

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs
Loading...

Reviews for Human ERR beta/NR3B2 Antibody

There are currently no reviews for this product. Be the first to review Human ERR beta/NR3B2 Antibody and earn rewards!

Have you used Human ERR beta/NR3B2 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review