Human FGFR5/FGFRL1 Antibody

Catalog # Availability Size / Price Qty
AF2257
AF2257-SP
Product Details
Citations (1)
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Human FGFR5/FGFRL1 Antibody Summary

Species Reactivity
Human
Specificity
Detects human FGF R5/FGFRL1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 65% cross‑reactivity with recombinant mouse (rm) FGF R5 and rmFGF R5 beta is observed and less than 1% cross-reactivity with recombinant human (rh) FGF R1 alpha  (IIIb), rhFGF R1 alpha  (IIIc), rhFGF R1 beta  (IIIb), rhFGF R1 beta  (IIIc), rhFGF R2 alpha  (IIIb), rhFGF R2 alpha  (IIIc), rhFGF R2 beta  (IIIb), rhFGF R2 beta  (IIIc), rhFGF R3 alpha  (IIIb), rhFGF R3 (IIIc), and rhFGF R4 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human FGF R5/FGFRL1
Ala25-Pro378
Accession # Q8N441
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human FGF R5/FGFRL1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FGFR5/FGFRL1

FGF R5 is a widely expressed type I transmembrane protein belonging to the FGF receptor family. It shares approximately 32% amino acid sequence identity to the extracellular domains of FGF R1-4, but does not contain a cytoplasmic tyrosine kinase domain.

Long Name
Fibroblast Growth Factor Receptor-like 1
Entrez Gene IDs
53834 (Human); 116701 (Mouse)
Alternate Names
FGF homologous factor receptor; FGF R5; FGF receptor-like protein 1; FGFR5; FGFR-5; FGFRL1; FGFR-like protein; FHFR; Fibroblast growth factor receptor 5; fibroblast growth factor receptor-like 1

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Citation for Human FGFR5/FGFRL1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Rapid fusion and syncytium formation of heterologous cells upon expression of the FGFRL1 receptor.
    Authors: Steinberg F, Gerber SD, Rieckmann T
    J. Biol. Chem., 2010-09-17;285(48):37704-15.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot

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