Human Frizzled-10 (NP_009128) VersaClone cDNA

Catalog #: RDC0126 Datasheet / COA / SDS

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RDC0126

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Human Frizzled-10 (NP_009128) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: Frizzled-10

This group of G protein-coupled receptors consists of 10 structurally-related, seven transmembrane proteins with a divergent N-terminal signal peptide and a variable-length C-terminal tail. The Frizzled family proteins contain a highly conserved cysteine-rich domain and a variable length linker region. Frizzled proteins function as receptors for Wnt proteins and can activate canonical Wnt/beta-catenin signaling as well as non-canonical pathways (Planar Cell Polarity and Wnt/Ca²⁺Pathways). Wnt/Frizzled signaling is involved in a variety of developmental processes including cell fate determination, cell polarity, tissue patterning, and control of cell proliferation. Activation of a given Wnt/Frizzled signaling cascade is dependent on the Wnt ligand and the cell context. Frizzled proteins also form co-receptor complexes with LRP, ROR, and Ryk molecules.

Entrez Gene IDs

11211 (Human); 93897 (Mouse); 64512 (Rat)

Alternate Names

CD350 antigen; CD350; frizzled (Drosophila) homolog 10; frizzled homolog 10 (Drosophila); Frizzled10; Frizzled-10; Fz10; FZ-10; FZD10; FzE7; hFz10