Human FSHR APC-conjugated Antibody Summary
Accession # M65085
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of FSH R in OVCAR‑3 Human Cell Line by Flow Cytometry. OVCAR-3 human ovarian carcinoma cell line was stained with Mouse Anti-Human FSH R APC-conjugated Monoclonal Antibody (Catalog # FAB65591A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins.
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Detection of FSH R in HEK293 Human Cell Line Transfected with Human FSH R and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human FSH R and eGFP was stained with Mouse Anti-Human FSH R APC-conjugated Monoclonal Antibody (Catalog # FAB65591A). Quadrant markers were set based on control antibody staining (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: FSHR
Follicle Stimulating Hormone Receptor (FSH R), also called Follitropin Receptor or LGR1, is a 695 amino acid (aa), ~87 kDa 7-transmembrane receptor of the leucine-rich repeat glycoprotein hormone receptor subfamily of GPCRs. It is expressed by ovarian granulosa cells and is essential for ovarian follicle maturation. In the male, it is expressed by Sertoli cells and plays a minor role in male fertility. Human FSH R shares 86% aa sequence identity with mouse and rat FSH R within the 349 aa N‑terminal extracellular domain. A 754 aa isoform contains an inserted sequence at aa 75.
Product Datasheets
Citation for Human FSHR APC-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
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Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription factor overexpression
Authors: MD Pierson Sm, CC Kramme, PRJ Fortuna, JL Adams, R Su, E Dong, M Kobayashi, G Brixi, VS Kavirayuni, E Tysinger, RE Kohman, T Shioda, P Chatterjee, GM Church
Elife, 2023-02-21;12(0):.
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