Human GPRC5D PE-conjugated Antibody

Catalog #: FAB63001P Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB63001P-100

Detection of GPRC5D in MM.1S by Flow Cytometry

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Human GPRC5D PE-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects HEK293 cells transfected with GPRC5D by Flow.

Source

Monoclonal Mouse IgG2a Clone # 571932

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

CyTOF-ready

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of GPRC5D in MM.1S by Flow Cytometry MM.1S were stained with Mouse Anti-Human GPRC5D PE‑conjugated Monoclonal Antibody (Catalog # FAB63001P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Flow Cytometry

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Detection of GPRC5D in HEK293 cells transfected with Human GPRC5D and eGFP vs HEK293 cells transfected with Human GPRC5A and eGFP by Flow Cytometry HEK293 cells transfected with Human GPRC5D and eGFP (A) vs HEK293 cells transfected with Human GPRC5A and eGFP (B) were stained with Mouse Anti-Human GPRC5D PE‑conjugated Monoclonal Antibody (Catalog # FAB63001P). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: GPRC5D

G-protein coupled receptor family C group 5 member D (GPRC5D) is a retinoic acid-inducible 40 kDa protein with seven transmembrane segments and a short N‑terminal extracellular region. It is expressed in keratinizing epithelial cells, the pancreas, kidney, small intestine, spleen, and testis. Alternate splicing generates two additional isoforms with substitutions or truncations in the cytoplasmic tail. Human GPRC5D shares approximately 80% aa sequence identity with mouse and rat GPRC5D.

Long Name

G Protein-coupled Receptor, Family D, Group 5, Member D

Entrez Gene IDs

55507 (Human); 93746 (Mouse); 500349 (Rat)

Alternate Names

G protein-coupled receptor, family C, group 5, member D; GPRC5D; G-protein coupled receptor family C group 5 member D; MGC129713; MGC129714; orphan G-protein coupled receptor