Human IFN-alpha Fluorescein-conjugated Antibody

Name: Human IFN-alpha Fluorescein-conjugated Antibody
Brand: R&D Systems
SKU: 21112-3
Price: 415 USD

Catalog #: 21112-3 Datasheet / COA / SDS

Discontinued Product

21112-3 has been discontinued.

View all IFN-alpha products.

All IFN-alpha Antibodies

Product Details

FAQs

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human IFN-alpha Fluorescein-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human IFN‑ alpha

Source

Monoclonal Mouse IgG₁ Clone # MMHA-11

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Human Leukocyte Interferon

Formulation

Phosphate-buffered saline (PBS) containing 1% BSAand 0.05% Kathon, pH 7.2.

Label

Fluorescein (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

A549 (human lung carcinomacell line). It is recommended that each investigator determine appropriate dilutions for other cell lines.

Immunohistochemistry

It is recommended that each investigator determine appropriate dilutions for individual use.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. Store at 2-8°C.

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Long Name

Interferon alpha

Entrez Gene IDs

3440 (Human)

Alternate Names

IFNA; IFNA2; IFNA2b; IFNalpha; IFN-alpha; IFN-alphaA; INFA2; interferon alpha 2; LeIF D