Human IL-34 Antibody

Name: Human IL-34 Antibody
Brand: R&D Systems
SKU: MAB52651
Rating: 2 (1 reviews)

Catalog #: MAB52651 1 Review Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB52651
MAB52651-SP

All IL-34 Antibodies

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Reviews (1)

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human IL-34 Antibody Summary

Species Reactivity

Human

Specificity

Detects human IL-34 in sandwich immunoassays. In this format, no cross-reactivity with recombinant mouse IL-34 is observed.

Source

Monoclonal Mouse IgG₁ Clone # 578410

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant human IL-34
Asn21-Pro242
Accession # Q6ZMJ4

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Human IL-34 Sandwich Immunoassay

Recommended Concentration

Reagent

ELISA Capture (Matched Antibody Pair)

2-8 µg/mL

Use in combination with:

Detection Reagent: Human IL‑34 Biotinylated Antibody (Catalog # BAM52652)

Standard: Recombinant Human IL-34 Protein (Catalog # 5265-IL)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-34

Interleukin 34 (IL-34) is secreted as a homodimer consisting of 39 kDa monomers. It belongs to no known cytokine family. The mature chain contains one potential site for N-linked glycosylation. IL-34 is widely expressed, but it is most abundant in the spleen. The receptor for IL-34 is colony-stimulating factor 1 receptor (CSF‑1R). Functionally, IL-34 stimulates monocyte viability.

Long Name

Interleukin 34

Entrez Gene IDs

146433 (Human); 76527 (Mouse)

Alternate Names

C16orf77; IL34; IL-34; interleukin 34