Human KIR2DS5/CD158g PE-conjugated Antibody

Catalog #: FAB8920P Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB8920P-100

Detection of KIR2DS5/CD158g in Human PBMCs by Flow Cytometry.

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Human KIR2DS5/CD158g PE-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human KIR2DS5/CD158g in direct ELISAs.

Source

Monoclonal Rabbit IgG Clone # 1165A

Purification

Protein A or G purified from cell culture supernatant

Immunogen

NS0 mouse myeloma cell line transfected with human KIR2DS5/CD158g
His22-His245
Accession # Q14953

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of KIR2DS5/CD158g in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with (A) Mouse Anti-Human KIR2DS5/CD158g PE-conjugated Monoclonal Antibody (Catalog # FAB8920P) or (B) Rabbit IgG PE-conjugated Isotype Control (Catalog # IC1051P) and Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A). View our protocol for Staining Membrane-associated Proteins.

Flow Cytometry

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Detection of KIR2DS5/CD158g in BaF3 Mouse Cell Line Transfected with KIR2DS5/CD158g by Flow Cytometry. BaF3 mouse pro-B cell line transfected with KIR2DS5/CD158g were stained with Rabbit Anti-Human KIR2DS5/CD158g PE‑conjugated Monoclonal Antibody (Catalog # FAB8920P, filled histogram) or control antibody Rabbit IgG PE‑conjugated Monoclonal Antibody (IC1051P, open histogram). Staining was performed Staining Membrane-associated Proteins protocol.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: KIR2DS5/CD158g

Killer-immunoglobulin-like receptors (KIR) are polymorphous activating and inhibitory receptors expressed on the surface of NK cells and some T cells. KIR genes are highly homologous. KIR proteins expressing the long (L) cytoplasmic domain are inhibitory, while KIRs with short (S) cytoplasmic domains are activating. Thus, KIR2DS5 is an activating receptor for NK cells, and is thought to play a role in NK cell function in response to a number of conditions. While many KIR proteins bind HLA-class I molecules, the ligand(s) for KIR2DS5 remain unknown.

Long Name

Killer Cell Immunoglobulin-like Receptor, Two Domains, Short Cytoplasmic Tail, 5

Entrez Gene IDs

3810 (Human)

Alternate Names

killer cell immunoglobulin-like receptor 2DS5; CD158g; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5; KIR2DS5; NKAT9