Human LPAR4/LPA4 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB10217U Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB10217U-100UG
R&D Systems Antibodies
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Human LPAR4/LPA4 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human LPAR4/LPA4 in direct ELISAs.
Source
Monoclonal Mouse IgG2A Clone # 561203
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Human embryonic kidney cell line HEK293-derived transfected with human LPAR4/LPA4
Accession # Q99677
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
HEK293 Human Cell Line Transfected with Human LPAR4 and eGFP

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: LPAR4/LPA4

Lysophosphatidic acid receptor 4, also known as LPA4, P2Y purinoceptor 9 (P2RY9) or GPR23, is a protein that in humans is encoded by the LPAR4 gene. LPA4 is a G protein-coupled receptor (GPCR) that binds the lipid signaling molecule lysophosphatidic acid (LPA) and mediates diverse cellular activities. Most LPA receptors share similarities with members of the S1P1/Edg family. GPA4, originally named P2Y9/GPR23, has been described as a fourth LPA receptor, LPA4, that together with LPA5 and LPA6 form a subfamily of LPA receptors structurally distant from the Edg family.  

Long Name
Lysophosphatidic Acid Receptor 4
Entrez Gene IDs
2846 (Human); 78134 (Mouse)
Alternate Names
G protein-coupled receptor 23; GPCR23; GPR23; GPR23P2Y purinoceptor 9; LPA4LPA-4; LPAR4; lysophosphatidic acid receptor 4; P2RY9; P2RY9G-protein coupled receptor 23; P2Y5-like receptor; P2Y5-LIKE; P2Y9; P2Y9LPA receptor 4; Purinergic receptor 9

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Product Specific Notices


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

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