Human LXR alpha/NR1H3 Antibody (Clone K8607)

Name: Human LXR alpha/NR1H3 Antibody (Clone K8607)
Brand: R&D Systems
SKU: PP-K8607-00
Rating: 5 (1 reviews)

Catalog #: PP-K8607-00
5 Citations 1 Review Datasheet / COA / SDS

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PP-K8607-00

All LXR alpha/NR1H3 Antibodies

Product Details

Citations (5)

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Reviews (1)

Summary Preparation and Storage Reconstitution Calculator Product Datasheets Related Research Areas

Human LXR alpha/NR1H3 Antibody (Clone K8607) Summary

Species Reactivity

Human

Source

Monoclonal Mouse IgG2a Clone # K8607

Formulation

A liquid formulation in physiologic saline with 0.1% NaN₃.

Applications

Recommended Concentration

Sample

Western Blot

Please refer to the PDF datasheet for specifications.

Immunoprecipitation

Please refer to the PDF datasheet for specifications.

Gel Supershift Assay

Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: LXR alpha/NR1H3

Long Name

Liver X Receptor alpha

Entrez Gene IDs

10062 (Human)

Alternate Names

alpha; Liver X receptor alpha; liver X receptor-alpha; LXR alpha; LXRA; NR1H3; Nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD-1

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human LXR alpha/NR1H3 Antibody (Clone K8607)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
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High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway.
Authors: Dong B, Kan C, Singh A, Liu J
J Lipid Res, 2013-02-20;54(5):1241-54.
Species: Hamster
Sample Types: Tissue Homogenates
Applications: Western Blot
Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters
Authors: Minhao Wu, Bin Dong, Aiqin Cao, Hai Li, Jingwen Liu
Atherosclerosis
Dietary soy protein isolate attenuates metabolic syndrome in rats via effects on PPAR, LXR, and SREBP signaling.
Authors: Ronis MJ, Chen Y, Badeaux J, Badger TM
J. Nutr., 2009-06-10;139(8):1431-8.
Species: Rat
Sample Types: Cell Lysates
Applications: Western Blot
Protein kinase C alpha modulates liver X receptor alpha transactivation.
Authors: Delvecchio CJ, Capone JP
J. Endocrinol., 2008-04-01;197(1):121-30.
Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
Sample Types: Cell Lysates
Applications: Western Blot
Liver X receptors alpha and beta regulate renin expression in vivo.
Authors: Morello F, de Boer RA, Steffensen KR, Gnecchi M, Chisholm JW, Boomsma F, Anderson LM, Lawn RM, Gustafsson JK, Lopez-Ilasaca M, Pratt RE, Dzau VJ
J. Clin. Invest., 2005-07-01;115(7):1913-22.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P