Human Meteorin-like/METRNL Antibody

Catalog #: MAB78671 Datasheet / COA / SDS

Recombinant Monoclonal Antibody

Catalog #	Availability	Size / Price	Qty
MAB78671-100
MAB78671-SP

Human Meteorin‑like/METRNL ELISA Standard Curve.

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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Meteorin-like/METRNL Antibody Summary

Species Reactivity

Human

Specificity

Detects human Meteorin‑like/METRNL in direct ELISAs.

Source

Recombinant Monoclonal Mouse IgG₁ Clone # 781710R

Purification

Protein A or G purified from cell culture supernatant

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Meteorin‑like/METRNL
Gln46-Asp311
Accession # Q641Q3

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

ELISA

This antibody functions as an ELISA detection antibody when paired with Mouse Anti-Human Meteorin‑like/METRNL Monoclonal Antibody (Catalog # MAB7867).

This product is intended for assay development on various assay platforms requiring antibody pairs. We recommend the Human Meteorin-like/METRNL DuoSet ELISA Kit (Catalog # DY7867-05) for convenient development of a sandwich ELISA.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

ELISA

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Human Meteorin‑like/METRNL ELISA Standard Curve. Recombinant Human Meteorin-like/METRNL protein was serially diluted 2-fold and captured by Mouse Anti-Human Meteorin-like/METRNL Monoclonal Antibody (Catalog # MAB7867) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human Meteorin-like/METRNL Monoclonal Antibody (Catalog # MAB78671) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998) followed by Substrate Solution (Catalog # DY999) and stopping the enzymatic reaction with Stop Solution (Catalog # DY994).

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Meteorin-like/METRNL

METRNL (Meteorin-like) is a cytoplasmic 30 kDa (predicted) member of the meteorin family of proteins. The name meteorin derives from the ability of the founding family member meteorin to transform glia into cells containing an extensive, meteor-like tail. It is expressed by neurons, and appears to function as a primer molecule that sets the stage for either cell differentiation or neurite outgrowth when it acts with Dclk1 and SerpinB1. Mature human METRNL is 266 amino acids (aa) in length (aa 46-311). It reportedly contains a signal sequence (aa 1-45), which suggests it may be secreted. Mature human and mouse METRNL share 79% aa sequence identity.

Entrez Gene IDs

284207 (Human); 210029 (Mouse); 316842 (Rat)

Alternate Names

Meteorin like; meteorin, glial cell differentiation regulator-like; meteorin-like protein; Meteorin-like; METRNL; MGC99788