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Human/Mouse Myeloperoxidase/MPO Antibody

Catalog #: AF3667
165 Citations 4 Reviews Datasheet / COA / SDS
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Detection of Human/Mouse Myeloperoxidase/MPO by Western Blot.
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Citations (165)
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Human/Mouse Myeloperoxidase/MPO Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects human and mouse Myeloperoxidase/MPO in Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse EPPO is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse MPO
Met16-Thr718
Accession # P11247
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.5 µg/mL
See below
Simple Western
5 µg/mL
See below
Immunohistochemistry
1-15 µg/mL
See below
Dual RNAscope ISH-IHC
5-15 µg/mL
Immersion fixed paraffin-embedded sections of mouse spleen
Immunocytochemistry
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Human/Mouse Myeloperoxidase/MPO antibody by Western Blot. View Larger

Detection of Human/Mouse Myeloperoxidase/MPO by Western Blot. Western blot shows lysates of HL-60 human acute promyelocytic leukemia cell line, human neutrophil cells, and mouse spleen tissue. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF019). A specific band was detected for Myeloperoxidase/MPO at approximately 60 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 2.

Immunocytochemistry Myeloperoxidase/MPO antibody in Mouse Splenocytes by Immunocytochemistry (ICC). View Larger

Myeloperoxidase/MPO in Mouse Splenocytes. Myeloperoxidase/MPO was detected in immersion fixed mouse splenocytes using Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

For human Immunocytochemistry samples, we recommend Mouse Anti-Human Myeloperoxidase/ MPO Monoclonal Antibody (MAB3174).

Immunohistochemistry Myeloperoxidase/MPO antibody in Mouse Spleen Tissue by Immunohistochemistry (IHC-P). View Larger

Myeloperoxidase/MPO in Mouse Spleen Tissue. Myeloperoxidase/MPO was detected in immersion fixed paraffin-embedded sections of mouse spleen tissue using Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) at 1 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to lymphocytes. Staining was performed using our IHC Staining with VisUCyte HRP Polymer Detection Reagents.

For human Immunohistochemistry samples, we recommend Mouse Anti-Human Myeloperoxidase/ MPO Monoclonal Antibody (MAB3174).

Simple Western Detection of Mouse Myeloperoxidase/MPO antibody by Simple Western<SUP>TM</SUP>. View Larger

Detection of Mouse Myeloperoxidase/MPO by Simple WesternTM. Simple Western lane view shows lysates of mouse spleen tissue, loaded at 0.2 mg/mL. A specific band was detected for Myeloperoxidase/MPO at approximately 67 kDa (as indicated) using 5 µg/mL of Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Immunohistochemistry Detection of Human Myeloperoxidase/MPO by Immunohistochemistry View Larger

Detection of Human Myeloperoxidase/MPO by Immunohistochemistry SAA levels positively correlate with tumour-associated neutrophil infiltration. (A) Representative images of MPO-positive neutrophils in a lung adenocarcinoma tumour section (original magnification ×200). (B) Neutrophils are significantly elevated in tumours compared to control tissue biopsies, which was confirmed by (C) paired analysis of tumour and adjacent control lung tissue. (D) Circulating SAA levels were elevated in lung adenocarcinoma patients as determined by ELISA. (E) SAA transcript levels were not increased in tumours as measured by RTqPCR and confirmed by (F) sub-analysis of the paired from the tumour and adjacent control tissue samples. (G) Tissue sections were stained for SAA, which identified positive staining within seromucinous glands and tumour-associated macrophages (original magnification ×200). (H) Spearman correlation was used to assess associations between SAA transcript levels and tumour infiltrating neutrophil density (r = 0.51, *** p < 0.001). **** p < 0.0001, ** p < 0.01, ## p < 0.01. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/34203378), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse Myeloperoxidase/MPO by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse Myeloperoxidase/MPO by Immunocytochemistry/Immunofluorescence Epicutaneous lugdunin recruits phagocytic cells. a Schematic overview of the mouse experiments: 6–8-week-old female C5BL/6 wild-type (WT), MyD88-ko, or 5xTLR-ko mice were epicutaneously treated with 1.5 µg lugdunin or phosphate-buffered saline (PBS) as a control. After 24 h, mice were euthanized, immune cells were isolated from treated skin areas, and immune cell composition was analyzed by flow cytometry. b Shown is the mean percentage of CD45+  live cells in mouse skin of 10 C57BL/6 WT mice ± s.e.m. One mouse is represented as two dots analyzed by two different stainings. c Pie charts show the mean percentage of the different immune cell subsets in the skin of 10 WT mice after 24 h of PBS or lugdunin treatment. d Shown are representative flow cytometry data (left panel) and the mean percentage of neutrophils (Ly6C+Ly6G+) and monocytes (Ly6C+Ly6G−) pregated on CD11b+CD45+ live cells (see Supplementary Fig. 3a, f for the gating strategy) in mouse skin ± s.e.m. One dot represents one mouse. *P < 0.05. e Representative myeloperoxidase (MPO)-stained paraffin-embedded mouse skin sections. Scale bar, 100 µM. Source data are provided as a Source Data file Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31227691), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse Myeloperoxidase/MPO by Western Blot View Larger

Detection of Mouse Myeloperoxidase/MPO by Western Blot Levels of CTGF, TGF-beta, MPO, and VEGF in silicone implant-induced capsular tissues determined by western blotting (a). A low signal was obtained for CTGF (b) and TGF-beta (c) protein in PN-KO mice (n = 6), whereas a strong signal was detected in the C57BL/6 mice (n = 6). Compared with the control group (n = 6), the levels of MPO (d) and VEGF (e) protein were downregulated in the PN-KO group (n = 6). Relative expression levels normalized to the housekeeping gene beta -actin. ∗∗p < 0.001. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/29854742), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse Myeloperoxidase/MPO by Western Blot View Larger

Detection of Mouse Myeloperoxidase/MPO by Western Blot LCN2 mAb limited blood–brain barrier leakage and infiltration of neutrophils after tMCAo. Representative images (A) and quantification (B) of Evans blue extravasation in the ipsilateral hemispheres of mice treated with control IgG (con) and LCN2 mAb (n = 5 per group) after one hour of tMCAo and 23 h after reperfusion. The concentration of Evans blue dye in the ipsilateral hemispheres of mice treated with LCN2 mAb was significantly decreased (** p < 0.01) as compared with that in the ipsilateral hemispheres of mice treated with control IgG (two-tailed, unpaired t test); (C) The expression level of the tight junction protein claudin-5 was analyzed after treatments with control IgG and LCN2 mAb (n = 4 per group). The ipsilateral (i) and contralateral (c) hemispheres isolated at 23 h after tMCAo were analyzed by Western blotting using antibodies against claudin-5. Representative Western blot showing the expression of claudin-5 (~22 kDa) in brain homogenates. beta -actin served as a loading control; (D) The level of claudin-5 immunoreactivity normalized to beta -actin (claudin-5/actin) in the ipsilateral hemispheres in mice treated with LCN2 mAb was significantly higher than that in the ipsilateral hemispheres of mice that received the control IgG (* p < 0.05, one-tailed, unpaired t test); (E,F) Neutrophil infiltration was analyzed by measuring the levels of MPO in brain homogenates. The ipsilateral (i) and contralateral (c) hemispheres of mice treated with control IgG (con) and LCN2 mAb (n = 4 per group) isolated at 23 h after tMCAo were analyzed by Western blotting using antibodies against MPO; (E) Representative Western blots show the expression of MPO heavy chain (~55 kD) in brain homogenates; (F) The level of MPO immunoreactivity normalized to beta -actin (MPO/actin) was significantly reduced in the ipsilateral hemispheres of mice treated with LCN2 mAb (* p < 0.05, one-tailed, unpaired t test) as compared with that in the ipsilateral hemisphere of mice that received control IgG. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32872405), licensed under a CC-BY license. Not internally tested by R&D Systems.

In-situ Hybridization View Larger

Detection of Myeloperoxidase/MPO in Mouse Spleen. Formalin-fixed paraffin-embedded tissue sections of mouse spleen were probed for MPO mRNA (ACD RNAScope Probe, catalog #603091; Fast Red chromogen, ACD catalog # 322750). Adjacent tissue section was processed for immunohistochemistry using goat anti-mouse MPO polyclonal antibody (R&D Systems catalog # AF3667) at 1ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-goat IgG VisUCyte HRP Polymer Antibody (Catalog # VC004) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to cell surface.

Immunohistochemistry Detection of Human Human/Mouse Myeloperoxidase/MPO Antibody by Immunohistochemistry View Larger

Detection of Human Human/Mouse Myeloperoxidase/MPO Antibody by Immunohistochemistry Immunofluorescence staining reveals that flagellum-deficiency abolishes P. aeruginosa-induced NET formation.Human PMNs were exposed to wild-type (WT) or flagellum-deficient strains of P. aeruginosa PAK flgC and PAO1 fliC, and NET release was documented. (A) Immunofluorescence staining of myeloperoxidase (MPO, green), citrullinated histone H4 (citH4, red), extracellular DNA (DAPI, blue) and their merged images are shown. Representative results, n = 3. (B) Quantitation of immunofluorescence images shown in panel (A). Based on nuclear morphology and co-staining with MPO and citH4, NET-forming PMNs were identified and their numbers quantitated compared to the total cell population (expressed as percentage of total). Mean+/-S.E.M., n = 3. One-way ANOVA, Tukey’s post hoc test. *, p<0.05; **, p<0.01. Nonstim., nonstimulated; WT, wild-type. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/27855208), licensed under a CC-BY license. Not internally tested by R&D Systems.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Myeloperoxidase/MPO

Myeloperoxidase (MPO) is a hemeprotein that belongs to the XPO subfamily of the heme peroxidase superfamily. MPO is synthesized as a preproprotein that undergoes proteolytic processing to generate a disulfide-linked heterodimer of the N-terminal beta -subunit (12 kDa) and C-terminal alpha subunit (60 kDa). Active MPO is a tetramer of two beta -subunits and two alpha -subunits that are also disulfide-linked through the two alpha -subunits. MPO is stored in granules and is an abundant protein in neutrophils and monocytes. MPO is released upon activation to catalyze the formation of powerful oxidants such as hypochlorous acid, which kills microbes. Unprocessed pro-MPO can also be released. Mouse MPO shares 87% amino acid sequence identity with that of human MPO.

Entrez Gene IDs
4353 (Human); 17523 (Mouse); 303413 (Rat)
Alternate Names
EC 1.11.1; EC 1.11.1.7; MPO; Myeloperoxidase

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Citations for Human/Mouse Myeloperoxidase/MPO Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

165 Citations: Showing 1 - 10
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  1. Oxidized Phospholipids and Neutrophil Elastase Coordinately Play Critical Roles in NET Formation
    Authors: Takuto Tokuhiro, Akane Ishikawa, Haruka Sato, Shunya Takita, Ayuri Yoshikawa, Ryoko Anzai et al.
    Frontiers in Cell and Developmental Biology
  2. DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis
    Authors: Jenying Deng, Yaan Kang, Chien-Chia Cheng, Xinqun Li, Bingbing Dai, Matthew H. Katz et al.
    JCI Insight
  3. Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19
    Authors: Rainer Kaiser, Alexander Leunig, Kami Pekayvaz, Oliver Popp, Markus Joppich, Vivien Polewka et al.
    JCI Insight
  4. Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy
    Authors: Leo Nicolai, Alexander Leunig, Sophia Brambs, Rainer Kaiser, Tobias Weinberger, Michael Weigand et al.
    Circulation
  5. Neutrophils homing into the retina trigger pathology in early age-related macular degeneration
    Authors: Sayan Ghosh, Archana Padmanabhan, Tanuja Vaidya, Alan M. Watson, Imran A. Bhutto, Stacey Hose et al.
    Communications Biology
  6. METTL3-mediated N6-methyladenosine exacerbates ferroptosis via m6A-IGF2BP2-dependent mitochondrial metabolic reprogramming in sepsis-induced acute lung injury
    Authors: Hao Zhang, Dan Wu, Yanghanzhao Wang, Kefang Guo, Charles B. Spencer, Lilibeth Ortoga et al.
    Clin Transl Med
  7. Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis
    Authors: Harada Y, Zhang J, Imari K et al.
    Pain
  8. The Absence of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) Promotes Pro-Angiogenic Microenvironmental Conditions and Angiogenesis in Muscle Tissue Ischemia
    Authors: Matthias Kübler, Sebastian Beck, Lisa Lilian Peffenköver, Philipp Götz, Hellen Ishikawa-Ankerhold, Klaus T. Preissner et al.
    International Journal of Molecular Sciences
  9. Neutrophil extracellular traps-triggered impaired autophagic flux via METTL3 underlies sepsis-associated acute lung injury
    Authors: Mengdi Qu, Zhaoyuan Chen, Zhiyun Qiu, Ke Nan, Yanghanzhao Wang, Yuxin Shi et al.
    Cell Death Discovery
  10. Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses
    Authors: Kirsti Hornigold, Julia Y. Chu, Stephen A. Chetwynd, Polly A. Machin, Laraine Crossland, Chiara Pantarelli et al.
    Frontiers in Immunology
  11. Age-Dependent Changes of Adipokine and Cytokine Secretion From Rat Adipose Tissue by Endogenous and Exogenous Toll-Like Receptor Agonists
    Authors: Verena Peek, Elena Neumann, Tomohiro Inoue, Sandy Koenig, Fabian Johannes Pflieger, Rüdiger Gerstberger et al.
    Frontiers in Immunology
  12. A TLR–CXCL1 pathway in DRG neurons induces neutrophil accumulation in the DRG and mechanical allodynia in EAE mice
    Authors: Jing Zhang, Yuka Harada, Yoshinori Hayashi
    Scientific Reports
  13. Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice
    Authors: Mei Yang, Xinmiao Zhou, Stuart W.A. Pearce, Zhisheng Yang, Qishan Chen, Kaiyuan Niu et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  14. Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
    Authors: Ramona Schulz-Heddergott, Nadine Stark, Shelley J. Edmunds, Jinyu Li, Lena-Christin Conradi, Hanibal Bohnenberger et al.
    Cancer Cell
  15. Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCII(hi) neutrophils
    Authors: Ma T, Tang Y, Wang T et al.
    Signal Transduction and Targeted Therapy
  16. FGF19‐Induced Inflammatory CAF Promoted Neutrophil Extracellular Trap Formation in the Liver Metastasis of Colorectal Cancer
    Authors: Chen Li, Tianli Chen, Jialiang Liu, Yue Wang, Chunhuan Zhang, Lu Guo et al.
    Advanced Science
  17. Lipopolysaccharide-Stimulated Human Fetal Membranes Induce Neutrophil Activation and Release of Vital Neutrophil Extracellular Traps
    Authors: Mancy Tong, Julie A. Potter, Gil Mor, Vikki M. Abrahams
    The Journal of Immunology
  18. Neutrophil Extracellular Traps Are Found in Bronchoalveolar Lavage Fluids of Horses With Severe Asthma and Correlate With Asthma Severity
    Authors: Pierre Janssen, Irene Tosi, Alexandre Hego, Pauline Maréchal, Thomas Marichal, Coraline Radermecker
    Frontiers in Immunology
  19. CLEC5A and TLR2 are critical in SARS-CoV-2-induced NET formation and lung inflammation
    Authors: Sung PS, Yang SP, Peng YC et al.
    Journal of biomedical science
  20. Inhibition of MPO (Myeloperoxidase) Attenuates Endothelial Dysfunction in Mouse Models of Vascular Inflammation and Atherosclerosis
    Authors: David Cheng, Jihan Talib, Christopher P. Stanley, Imran Rashid, Erik Michaëlsson, Eva-Lotte Lindstedt et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  21. Immunoregulatory Monocyte Subset Promotes Metastasis Associated With Therapeutic Intervention for Primary Tumor
    Authors: Takumi Shibuya, Asami Kamiyama, Hirotaka Sawada, Kenta Kikuchi, Mayu Maruyama, Rie Sawado et al.
    Frontiers in Immunology
  22. Aspirin-Triggered Resolvin D1 Reduces Proliferation and the Neutrophil to Lymphocyte Ratio in a Mutant KRAS-Driven Lung Adenocarcinoma Model
    Authors: Amanda Vannitamby, Mohamed I. Saad, Christian Aloe, Hao Wang, Beena Kumar, Ross Vlahos et al.
    Cancers (Basel)
  23. C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps
    Authors: Bruna M. Silva, Giovanni F. Gomes, Flavio P. Veras, Seppe Cambier, Gabriel V.L. Silva, Andreza U. Quadros et al.
    Journal of Clinical Investigation
  24. Infection with hypervirulent Mycobacterium tuberculosis triggers emergency myelopoiesis but not trained immunity
    Authors: Ana Raquel Maceiras, Diogo Silvério, Rute Gonçalves, Marcos S. Cardoso, Margarida Saraiva
    Frontiers in Immunology
  25. C3 Deficiency Leads to Increased Angiogenesis and Elevated Pro-Angiogenic Leukocyte Recruitment in Ischemic Muscle Tissue
    Authors: Philipp Götz, Anna Braumandl, Matthias Kübler, Konda Kumaraswami, Hellen Ishikawa-Ankerhold, Manuel Lasch et al.
    International Journal of Molecular Sciences
  26. Neutrophil extracellular traps regulate ischemic stroke brain injury
    Authors: Frederik Denorme, Irina Portier, John L. Rustad, Mark J. Cody, Claudia V. de Araujo, Chieko Hoki et al.
    Journal of Clinical Investigation
  27. Local Administration of Interleukin-1 Receptor Antagonist Improves Diabetic Wound Healing
    Authors: David P. Perrault, Athanasios Bramos, Xingtian Xu, Songtao Shi, Alex K. Wong
    Annals of Plastic Surgery
  28. In vitro Detection of Neutrophil Traps and Post-attack Cell Wall Changes in Candida Hyphae
    Authors: Alex Hopke, Robert T. Wheeler
    BIO-PROTOCOL
  29. Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation
    Authors: Tim DD Somerville, Giulia Biffi, Juliane Da beta ler-Plenker, Stella K Hur, Xue-Yan He, Krysten E Vance et al.
    eLife
  30. Endovascular mechanical thrombectomy in a child with COVID-19: Clot analysis reveals a novel pathway in the neuroinflammatory cascade resulting in large-vessel occlusion
    Authors: Vijay M M. Ravindra, Frederik Denorme, Matthew D. Alexander, Robert A. Campbell, Ramesh Grandhi
    Interv Neuroradiol
  31. Heterozygosity in the glutathione synthesis gene Gclm increases sensitivity to diesel exhaust particulate induced lung inflammation in mice
    Authors: Chad S. Weldy, Collin C. White, Hui-Wen Wilkerson, Timothy V. Larson, James A. Stewart, Sean E. Gill et al.
    Inhalation Toxicology
  32. Inhibition of neutrophil extracellular trap formation attenuates NLRP1-dependent neuronal pyroptosis via STING/IRE1 alpha pathway after traumatic brain injury in mice
    Authors: Yiyao Cao, Mingming Shi, Liang Liu, Yan Zuo, Haoran Jia, Xiaobin Min et al.
    Frontiers in Immunology
  33. Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments
    Authors: Jiang S, Chan CN, Rovira-ClavE X et al.
    Immunity
  34. CD11c regulates neutrophil maturation
    Authors: Lifei Hou, Richard A. Voit, Miho Shibamura-Fujiogi, Sophia Koutsogiannaki, Yunan Li, Yue Chen et al.
    Blood Advances
  35. Inflammation and neutrophil extracellular traps in cerebral cavernous malformation
    Authors: Anthony C. Y. Yau, Maria Ascencion Globisch, Favour Chinyere Onyeogaziri, Lei L. Conze, Ross Smith, Suvi Jauhiainen et al.
    Cellular and Molecular Life Sciences
  36. Targeting neutrophils extracellular traps (NETs) reduces multiple organ injury in a COVID-19 mouse model
    Authors: FP Veras, GF Gomes, BMS Silva, DB Caetité, CJLR Almeida, CMS Silva, AH Schneider, ES Corneo, CS Bonilha, SS Batah, R Martins, E Arruda, AT Fabro, JC Alves-Filh, TM Cunha, FQ Cunha
    Respiratory Research, 2023-03-02;24(1):66.
  37. Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis
    Authors: Zhang T, Yin C, Boyd D et al.
    Cell
  38. Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing mice
    Authors: Briana N. James, Cynthia Weigel, Christopher D. Green, Ryan D. R. Brown, Elisa N. D. Palladino, Anuj Tharakan et al.
    The FASEB Journal
  39. Neutrophil extracellular traps induce IL-1 beta production by macrophages in combination with lipopolysaccharide
    Authors: Zhongshuang Hu, Taisuke Murakami, Hiroshi Tamura, Johannes Reich, Kyoko Kuwahara-Arai, Toshiaki Iba et al.
    International Journal of Molecular Medicine
  40. Progesterone modulates the immune microenvironment to suppress ovalbumin-induced airway inflammation by inhibiting NETosis
    Authors: Wang, L;Huang, FY;Dai, SZ;Fu, Y;Zhou, X;Wang, CC;Tan, GH;Li, Q;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  41. Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease
    Authors: Rosenzweig, N;Kleemann, KL;Rust, T;Carpenter, M;Grucci, M;Aronchik, M;Brouwer, N;Valenbreder, I;Cooper-Hohn, J;Iyer, M;Krishnan, RK;Sivanathan, KN;Brandão, W;Yahya, T;Durao, A;Yin, Z;Chadarevian, JP;Properzi, MJ;Nowarski, R;Davtyan, H;Weiner, HL;Blurton-Jones, M;Yang, HS;Eggen, BJL;Sperling, RA;Butovsky, O;
    Nature medicine
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  42. Oncogenic KRAS-dependent stromal interleukin-33 directs the pancreatic microenvironment to promote tumor growth
    Authors: Donahue, KL;Watkoske, HR;Kadiyala, P;Du, W;Brown, K;Scales, MK;Elhossiny, AM;Espinoza, CE;Lasse Opsahl, EL;Griffith, BD;Wen, Y;Sun, L;Velez-Delgado, A;Renollet, NM;Morales, J;Nedzesky, NM;Baliira, RK;Menjivar, RE;Medina-Cabrera, PI;Rao, A;Allen, B;Shi, J;Frankel, TL;Carpenter, ES;Bednar, F;Zhang, Y;Pasca di Magliano, M;
    Cancer discovery
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  43. Modelling lung infection with Klebsiella pneumoniae after murine traumatic brain injury
    Authors: Shad, A;Rewell, SSJ;Macowan, M;Gandasasmita, N;Wang, J;Chen, K;Marsland, B;O'Brien, TJ;Li, J;Semple, BD;
    Journal of neuroinflammation
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  44. The Elevated Inflammatory Status of Neutrophils Is Related to In-Hospital Complications in Patients with Acute Coronary Syndrome and Has Important Prognosis Value for Diabetic Patients
    Authors: Barbu, E;Mihaila, AC;Gan, AM;Ciortan, L;Macarie, RD;Tucureanu, MM;Filippi, A;Stoenescu, AI;Petrea, SV;Simionescu, M;Balanescu, SM;Butoi, E;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: Western Blot, Immunocytochemistry
  45. Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice
    Authors: Su, Q;Su, C;Zhang, Y;Guo, Y;Liu, Y;Liu, Y;Yong, VW;Xue, M;
    International immunopharmacology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  46. Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments
    Authors: Abraham, MJ;Goncalves, C;McCallum, P;Gupta, V;Preston, SEJ;Huang, F;Chou, H;Gagnon, N;Johnson, NA;Miller, WH;Mann, KK;Del Rincon, SV;
    Cell & bioscience
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  47. Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model
    Authors: Wilkening, RV;Langouët-Astrié, C;Severn, MM;Federle, MJ;Horswill, AR;
    Cell reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  48. A dual role of lysophosphatidic acid type 2 receptor (LPAR2) in nonsteroidal anti-inflammatory drug-induced mouse enteropathy
    Authors: Hutka, B;Várallyay, A;László, SB;Tóth, AS;Scheich, B;Paku, S;Vörös, I;Pós, Z;Varga, ZV;Norman, DD;Balogh, A;Benyó, Z;Tigyi, G;Gyires, K;Zádori, ZS;
    Acta pharmacologica Sinica
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: Western Blot, IHC
  49. Inhibition of neutrophil extracellular trap formation ameliorates neuroinflammation and neuronal apoptosis via STING-dependent IRE1?/ASK1/JNK signaling pathway in mice with traumatic brain injury
    Authors: Shi, G;Liu, L;Cao, Y;Ma, G;Zhu, Y;Xu, J;Zhang, X;Li, T;Mi, L;Jia, H;Zhang, Y;Liu, X;Zhou, Y;Li, S;Yang, G;Liu, X;Chen, F;Wang, B;Deng, Q;Zhang, S;Zhang, J;
    Journal of neuroinflammation
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  50. An unexpected role of neutrophils in clearing apoptotic hepatocytes in vivo
    Authors: Cao, L;Ma, L;Zhao, J;Wang, X;Fang, X;Li, W;Qi, Y;Tang, Y;Liu, J;Peng, S;Yang, L;Zhou, L;Li, L;Hu, X;Ji, Y;Hou, Y;Zhao, Y;Zhang, X;Zhao, YY;Zhao, Y;Wei, Y;Malik, AB;Saiyin, H;Xu, J;
    eLife
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  51. Intravenous Administration of Human Umbilical Cord Mesenchymal Stromal Cells Leads to an Inflammatory Response in the Lung
    Authors: Hernandez Pichardo, A;Wilm, B;Liptrott, NJ;Murray, P;
    Stem cells international
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  52. Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCII(hi) neutrophils
    Authors: Ma T, Tang Y, Wang T et al.
    Signal Transduction and Targeted Therapy
  53. CD47 blockade ameliorates autoimmune vasculitis via efferocytosis of neutrophil extracellular traps
    Authors: Shiratori-Aso, S;Nakazawa, D;Kudo, T;Kanda, M;Ueda, Y;Watanabe-Kusunoki, K;Nishio, S;Iwasaki, S;Tsuji, T;Masuda, S;Tomaru, U;Ishizu, A;Atsumi, T;
    JCI insight
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  54. Neutrophils exacerbate acetaminophen-induced liver injury by producing cytotoxic interferon-?
    Authors: Wu, H;Guo, C;Liu, Z;Cai, J;Wang, C;Yi, H;Sanyal, A;Puri, P;Zhou, H;Wang, XY;
    International immunopharmacology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  55. SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling
    Authors: Perico, L;Morigi, M;Pezzotta, A;Locatelli, M;Imberti, B;Corna, D;Cerullo, D;Benigni, A;Remuzzi, G;
    Scientific reports
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  56. Immune Cells Localize to Sites of Corneal Erosions in C57BL/6 Mice
    Authors: Le, PM;Pal-Ghosh, S;Menko, AS;Stepp, MA;
    Biomolecules
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  57. Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils
    Authors: Huerga Encabo, H;Aramburu, IV;Garcia-Albornoz, M;Piganeau, M;Wood, H;Song, A;Ferrelli, A;Sharma, A;Minutti, CM;Domart, MC;Papazoglou, D;Gurashi, K;Llorian Sopena, M;Goldstone, R;Fallesen, T;Wang, Q;Ariza-McNaughton, L;Wiseman, DH;Batta, K;Gupta, R;Papayannopoulos, V;Bonnet, D;
    Cell stem cell
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  58. Inhibition of SARS-CoV-2-mediated thromboinflammation by CLEC2.Fc
    Authors: Sung, PS;Sun, CP;Tao, MH;Hsieh, SL;
    EMBO molecular medicine
    Species: Human, Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: Immunohistochemistry, Immunocytochemistry
  59. NOX4 as a critical effector mediating neuroinflammatory cytokines, myeloperoxidase and osteopontin, specifically in astrocytes in the hippocampus in Parkinson's disease
    Authors: N Boonpraman, S Yoon, CY Kim, JS Moon, SS Yi
    Redox Biology, 2023-04-10;62(0):102698.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot
  60. Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma
    Authors: X Peng, Y Li, W Zhao, S Yang, J Huang, Y Chen, Y Wang, Z Gong, X Chen, C Yu, S Cai, H Zhao
    International immunopharmacology, 2023-02-22;117(0):109719.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  61. Mice inflammatory responses to inhaled aerosolized LPS: effects of various forms of human alpha1-antitrypsin
    Authors: K Sivaraman, S Wrenger, B Liu, D Schaudien, C Hesse, G Gomez-Mari, S Perez-Luz, K Sewald, D DeLuca, MJ Wurm, P Pino, T Welte, B Martinez-D, S Janciauski
    Journal of leukocyte biology, 2023-01-10;113(1):58-70.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  62. IL-1beta neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH
    Authors: D Kucsera, VE Tóth, NV Sayour, T Kovács, TG Gergely, M Ruppert, T Radovits, A Fábián, A Kovács, B Merkely, P Ferdinandy, ZV Varga
    Scientific Reports, 2023-01-07;13(1):356.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  63. Inhibition of neutrophil elastase prevents cigarette smoke exposure-induced formation of neutrophil extracellular traps and improves lung function in a mouse model of chronic obstructive pulmonary disease
    Authors: K Wang, Y Liao, X Li, R Wang, Z Zeng, M Cheng, L Gao, D Xu, F Wen, T Wang, J Chen
    International immunopharmacology, 2022-12-07;114(0):109537.
    Species: Human
    Sample Types: Whole Cell
    Applications: ICC
  64. Scavenging dicarbonyls with 5'-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistance
    Authors: J Huang, H Tao, PG Yancey, Z Leuthner, LS May-Zhang, JY Jung, Y Zhang, L Ding, V Amarnath, D Liu, S Collins, SS Davies, MF Linton
    Molecular Metabolism, 2022-12-05;67(0):101651.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  65. A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein
    Authors: J Zeller, KS Cheung Tun, TL Nero, JD McFadyen, G Krippner, B Bogner, S Kreuzaler, J Kiefer, VK Horner, D Braig, H Danish, S Baratchi, M Fricke, X Wang, MG Kather, B Kammerer, KJ Woollard, P Sharma, CJ Morton, G Pietersz, MW Parker, K Peter, SU Eisenhardt
    Embo Molecular Medicine, 2022-12-05;0(0):e16236.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  66. Platelet-Neutrophil Association in NETs-Rich Areas in the Retrieved AIS Patient Thrombi
    Authors: GJ Pir, A Parray, R Ayadathil, SV Pananchikk, FA Mir, I Muhammad, A Abubakar, N Amir, S Hussain, KH Haroon, A Muhammad, Y Imam, SN Patro, N Akhtar, A Zakaria, S Kamran
    International Journal of Molecular Sciences, 2022-11-21;23(22):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  67. KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer
    Authors: J Yang, L Jin, HS Kim, F Tian, Z Yi, K Bedi, M Ljungman, M Pasca di M, H Crawford, J Shi
    Cancer Research, 2022-11-15;0(0):OF1-OF14.
    Species: Human, Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  68. CLEC5A is critical in Pseudomonas aeruginosa-induced acute lung injury
    Authors: PS Sung, YC Peng, SP Yang, CH Chiu, SL Hsieh
    JCI Insight, 2022-09-01;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  69. Epigallocatechin-3-gallate reduces neutrophil extracellular trap formation and tissue injury in severe acute pancreatitis
    Authors: H Li, C Qiao, L Zhao, Q Jing, D Xue, Y Zhang
    Journal of leukocyte biology, 2022-08-19;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  70. Integrating network pharmacology and transcriptomic validation to investigate the efficacy and mechanism of Mufangji decoction preventing lung cancer
    Authors: F Gao, Y Niu, L Sun, W Li, H Xia, Y Zhang, S Geng, Z Guo, H Lin, G Du
    Journal of ethnopharmacology, 2022-07-30;0(0):115573.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC/IF
  71. Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis
    Authors: N Caporarell, J Lee, TX Pham, DL Jones, J Guan, PA Link, JA Meridew, G Marden, T Yamashita, CA Osborne, AV Bhagwate, SK Huang, RF Nicosia, DJ Tschumperl, M Trojanowsk, G Ligresti
    Nature Communications, 2022-07-25;13(1):4170.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  72. Neutrophil Extracellular Traps Promote NLRP3 Inflammasome Activation and Glomerular Endothelial Dysfunction in Diabetic Kidney Disease
    Authors: A Gupta, K Singh, S Fatima, S Ambreen, S Zimmermann, R Younis, S Krishnan, R Rana, I Gadi, C Schwab, R Biemann, K Shahzad, V Rani, S Ali, PR Mertens, S Kohli, B Isermann
    Nutrients, 2022-07-20;14(14):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  73. High PANX1 Expression Leads to Neutrophil Recruitment and the Formation of a High Adenosine Immunosuppressive Tumor Microenvironment in Basal-like Breast Cancer
    Authors: W Chen, B Li, F Jia, J Li, H Huang, C Ni, W Xia
    Cancers, 2022-07-11;14(14):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  74. Deficiency of leukocyte-specific protein 1 (LSP1) alleviates asthmatic inflammation in a mouse model
    Authors: NPK Le, AF do Nascime, D Schneberge, CC Quach, X Zhang, GK Aulakh, W Dawicki, L Liu, JR Gordon, B Singh
    Respiratory Research, 2022-06-22;23(1):165.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  75. Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/neutrophil Elastase Signaling in Mice
    Authors: D Ye, J Yao, W Du, C Chen, Y Yang, K Yan, J Li, Y Xu, S Zang, Y Zhang, X Rong, R Zhang, A Xu, J Guo
    Cellular and Molecular Gastroenterology and Hepatology, 2022-06-02;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Cells, Whole Tissue
    Applications: ICC, IHC, Western Blot
  76. Depletion of gammadelta T Cells Leads to Reduced Angiogenesis and Increased Infiltration of Inflammatory M1-like Macrophages in Ischemic Muscle Tissue
    Authors: C Arnholdt, K Kumaraswam, P Götz, M Kübler, M Lasch, E Deindl
    Cells, 2022-04-29;11(9):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  77. Disulfiram inhibits neutrophil extracellular trap formation protecting rodents from acute lung injury and SARS-CoV-2 infection
    Authors: JM Adrover, L Carrau, J Da beta ler-Ple, Y Bram, V Chandar, S Houghton, D Redmond, JR Merrill, M Shevik, BR tenOever, SK Lyons, RE Schwartz, M Egeblad
    JCI Insight, 2022-03-08;0(0):.
    Species: Hamster
    Sample Types: Whole Tissue
    Applications: IHC
  78. Blocking the human common beta subunit of the GM-CSF, IL-5 and IL-3 receptors markedly reduces hyperinflammation in ARDS models
    Authors: H Wang, DJ Tumes, TR Hercus, KH Yip, C Aloe, R Vlahos, AF Lopez, N Wilson, CM Owczarek, S Bozinovski
    Cell Death & Disease, 2022-02-10;13(2):137.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  79. ADAM8 signaling drives neutrophil migration and ARDS severity
    Authors: C Conrad, D Yildiz, SJ Cleary, A Margraf, L Cook, U Schlomann, B Panaretou, JL Bowser, H Karmouty-Q, J Li, NK Berg, SC Martin, A Aljohmani, SF Moussavi-H, KM Wang, JJ Tian, M Magnen, C Valet, L Qiu, JP Singer, HK Eltzschig, CAPSys Stu, W Bertrams, S Herold, N Suttorp, B Schmeck, ZT Ball, A Zarbock, MR Looney, JW Bartsch
    JCI Insight, 2022-02-08;7(3):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  80. CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling
    Authors: KC Ngamsri, RA Putri, C Jans, K Schindler, A Fuhr, Y Zhang, J Gamper-Tsi, S Ehnert, FM Konrad
    International Journal of Molecular Sciences, 2021-12-17;22(24):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  81. Modulation of Cellular NAD+ Attenuates Cancer-Associated Hypercoagulability and Thrombosis via the Inhibition of Tissue Factor and Formation of Neutrophil Extracellular Traps
    Authors: W Cao, MY Zhu, SH Lee, SB Lee, HJ Kim, BO Park, CH Yoon, D Khadka, GS Oh, H Shim, TH Kwak, HS So
    International Journal of Molecular Sciences, 2021-11-08;22(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  82. Eosinophil extracellular traps drive asthma progression through neuro-immune signals
    Authors: Y Lu, Y Huang, J Li, J Huang, L Zhang, J Feng, J Li, Q Xia, Q Zhao, L Huang, S Jiang, S Su
    Nature Cell Biology, 2021-10-06;23(10):1060-1072.
    Species: Mouse
    Sample Types: BALF, Whole Cells
    Applications: ICC
  83. Sprague Dawley Rats Gaining Weight on a High Energy Diet Exhibit Damage to Taste Tissue Even after Return to a Healthy Diet
    Authors: F Harnischfe, F O'Connell, M Weiss, B Axelrod, A Hajnal, K Czaja, PM Di Lorenzo, R Dando
    Nutrients, 2021-08-31;13(9):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  84. ELMO1 signaling is a promoter of osteoclast function and bone loss
    Authors: S Arandjelov, JSA Perry, M Zhou, A Ceroi, I Smirnov, SF Walk, LS Shankman, I Cambré, S Onengut-Gu, D Elewaut, TP Conrads, KS Ravichandr
    Nature Communications, 2021-08-17;12(1):4974.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  85. Evidence of a Myenteric Plexus Barrier and Its Macrophage-Dependent Degradation During Murine Colitis: Implications in Enteric Neuroinflammation
    Authors: D Dora, S Ferenczi, R Stavely, VE Toth, ZV Varga, T Kovacs, I Bodi, R Hotta, KJ Kovacs, AM Goldstein, N Nagy
    Cellular and Molecular Gastroenterology and Hepatology, 2021-07-08;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  86. AMPK hyperactivation promotes dendrite retraction, synaptic loss, and neuronal dysfunction in glaucoma
    Authors: N Belforte, J Agostinone, L Alarcon-Ma, D Villafranc, F Dotigny, JL Cueva Varg, A Di Polo
    Molecular Neurodegeneration, 2021-06-29;16(1):43.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  87. NETosis in the pathogenesis of acute lung injury following cutaneous chemical burns
    Authors: R Surolia, FJ Li, Z Wang, M Kashyap, RK Srivastava, AM Traylor, P Singh, KG Dsouza, H Kim, JF Pittet, JW Zmijewski, A Agarwal, M Athar, A Ahmad, VB Antony
    JCI Insight, 2021-05-24;6(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  88. Absence of Cold-Inducible RNA-Binding Protein (CIRP) Promotes Angiogenesis and Regeneration of Ischemic Tissue by Inducing M2-Like Macrophage Polarization
    Authors: M Kübler, S Beck, S Fischer, P Götz, K Kumaraswam, H Ishikawa-A, M Lasch, E Deindl
    Biomedicines, 2021-04-07;9(4):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  89. Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer
    Authors: L Klemke, T De Oliveir, D Witt, N Winkler, H Bohnenberg, R Bucala, LC Conradi, R Schulz-Hed
    Cell Death & Disease, 2021-02-04;12(2):155.
    Species: Mouse
    Sample Types: Organoid
    Applications: IHC
  90. Immunomodulatory role of reactive oxygen species and nitrogen species during T cell-driven neutrophil-enriched acute and chronic cutaneous delayed-type hypersensitivity reactions
    Authors: R Mehling, J Schwenck, C Lemberg, C Trautwein, L Zizmare, D Kramer, A Müller, B Fehrenbach, I Gonzalez-M, L Quintanill, K Schröder, RP Brandes, M Schaller, W Ruf, M Eichner, K Ghoreschi, M Röcken, BJ Pichler, M Kneilling
    Theranostics, 2021-01-01;11(2):470-490.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  91. Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice
    Authors: MJ Thomas, E Major, A Benedek, I Horváth, D Máthé, R Bergmann, AM Szász, T Krenács, Z Benyó
    Cancers, 2020-12-21;12(12):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  92. Alveolar barrier disruption in varicella pneumonia is associated with neutrophil extracellular trap formation
    Authors: WJ Ouwendijk, HJ van den Ha, MW Delany, JJ van Kampen, GP van Nierop, T Mehraban, F Zaaraoui-B, WF van IJcken, JM van den Br, RD De Vries, AC Andeweg, GM Verjans
    JCI Insight, 2020-11-05;0(0):.
    Species: Primate
    Sample Types: Whole Tissue
    Applications: IHC
  93. Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis
    Authors: L Moreira-Te, PJ Stimpson, E Stavropoul, S Hadebe, P Chakravart, M Ioannou, IV Aramburu, E Herbert, SL Priestnall, A Suarez-Bon, J Sousa, KL Fonseca, Q Wang, S Vashakidze, P Rodríguez-, C Vilaplana, M Saraiva, V Papayannop, A O'Garra
    Nat Commun, 2020-11-04;11(1):5566.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  94. Immunohistological Analysis of Neutrophils and Neutrophil Extracellular Traps in Human Thrombemboli Causing Acute Ischemic Stroke
    Authors: F Essig, AM Kollikowsk, M Pham, L Solymosi, G Stoll, KG Haeusler, P Kraft, MK Schuhmann
    Int J Mol Sci, 2020-10-07;21(19):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  95. The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix
    Authors: S Taylor, M Whitfield, J Barratt, A Didangelos
    J. Immunol., 2020-09-11;0(0):.
    Species: Human, Rat
    Sample Types: Cell Lysates, Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  96. Neutrophil Extracellular Traps Impair Intestinal Barrier Function during Experimental Colitis
    Authors: EY Lin, HJ Lai, YK Cheng, KQ Leong, LC Cheng, YC Chou, YC Peng, YH Hsu, HS Chiang
    Biomedicines, 2020-08-05;8(8):.
    Species: Mouse
    Sample Types: Cell Lysates, Tissue Homogenates, Whole Tissue
    Applications: ELISA Capture, IHC
  97. Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury
    Authors: K Vaibhav, M Braun, K Alverson, H Khodadadi, A Kutiyanawa, A Ward, C Banerjee, T Sparks, A Malik, MH Rashid, MB Khan, MF Waters, DC Hess, AS Arbab, JR Vender, N Hoda, B Baban, KM Dhandapani
    Sci Adv, 2020-05-29;6(22):eaax8847.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  98. Histones, DNA, and Citrullination Promote Neutrophil Extracellular Trap Inflammation by Regulating the Localization and Activation of TLR4
    Authors: TD Tsouroukts, A Warnatsch, M Ioannou, D Hoving, Q Wang, V Papayannop
    Cell Rep, 2020-05-05;31(5):107602.
    Species: Human, Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  99. Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases
    Authors: RGS Chirivi, JWG van Rosmal, M van der Li, M Euler, G Schmets, G Bogatkevic, K Kambas, J Hahn, Q Braster, O Soehnlein, MH Hoffmann, HHGV Es, JMH Raats
    Cell. Mol. Immunol., 2020-03-20;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  100. Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils
    Authors: KL Fonseca, AR Maceiras, R Matos, L Simoes-Cos, J Sousa, B Cá, L Barros, AI Fernandes, S Mereiter, R Reis, J Gomes, G Tapia, P Rodríguez-, M Martín-Cés, S Vashakidze, S Gogishvili, K Nikolaishv, R Appelberg, F Gärtner, PNS Rodrigues, C Vilaplana, CA Reis, A Magalhães, M Saraiva
    Mucosal Immunol, 2020-03-13;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  101. Programmed 'disarming' of the neutrophil proteome reduces the magnitude of inflammation
    Authors: JM Adrover, A Aroca-Crev, G Crainiciuc, F Ostos, Y Rojas-Vega, A Rubio-Ponc, C Cilloniz, E Bonzón-Kul, E Calvo, D Rico, MA Moro, C Weber, I Lizasoaín, A Torres, J Ruiz-Cabel, J Vázquez, A Hidalgo
    Nat. Immunol., 2020-01-13;21(2):135-144.
    Species: Human
    Sample Types: Whole Cells
    Applications: Functional Assay
  102. Keratinocyte-derived I&kappaB? drives psoriasis and associated systemic inflammation
    Authors: S Lorscheid, A Müller, J Löffler, C Resch, P Bucher, FC Kurschus, A Waisman, K Schäkel, S Hailfinger, K Schulze-Os, D Kramer
    JCI Insight, 2019-11-14;4(22):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  103. Acute Liver Injury after CCl4 Administration is Independent of Smad7 Expression in Myeloid Cells
    Authors: J Endig, L Unrau, P Sprezyna, S Rading, M Karsak, D Goltz, LC Heukamp, G Tiegs, L Diehl
    Int J Mol Sci, 2019-11-06;20(22):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  104. Locally instructed CXCR4hi neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps
    Authors: C Radermecke, C Sabatel, C Vanwinge, C Ruscitti, P Maréchal, F Perin, J Schyns, N Rocks, M Toussaint, D Cataldo, SL Johnston, F Bureau, T Marichal
    Nat. Immunol., 2019-10-07;0(0):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  105. Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors
    Authors: K Bitschar, B Sauer, J Focken, H Dehmer, S Moos, M Konnerth, NA Schilling, S Grond, H Kalbacher, FC Kurschus, F Götz, B Krismer, A Peschel, B Schittek
    Nat Commun, 2019-06-21;10(1):2730.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  106. Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2
    Authors: PS Sung, TF Huang, SL Hsieh
    Nat Commun, 2019-06-03;10(1):2402.
    Species: Human, Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  107. Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells
    Authors: N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald
    JCI Insight, 2019-03-07;0(0):.
    Species: Xenograft
    Sample Types: Whole Tissue
    Applications: IHC-P
  108. Neutrophils escort circulating tumour cells to enable cell cycle progression
    Authors: BM Szczerba, F Castro-Gin, M Vetter, I Krol, S Gkountela, J Landin, MC Scheidmann, C Donato, R Scherrer, J Singer, C Beisel, C Kurzeder, V Heinzelman, C Rochlitz, WP Weber, N Beerenwink, N Aceto
    Nature, 2019-02-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  109. Qingnao dripping pills mediate immune-inflammatory response and MAPK signaling pathway after acute ischemic stroke in rats
    Authors: Z Zeng, Y Zhang, X Liang, F Wang, J Zhao, Z Xu, X Liu, X Liu
    J. Pharmacol. Sci., 2019-01-22;0(0):.
    Species: Rat
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  110. Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection
    Authors: J Rojas-Quin, X Wang, J Tipper, PR Burkett, J Zuñiga, AR Ashtekar, F Polverino, A Rout, I Yambayev, C Hernández, L Jimenez, G Ramírez, KS Harrod, CA Owen
    JCI Insight, 2018-12-20;3(24):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  111. GWAS for Interleukin-1? levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation
    Authors: S Offenbache, Y Jiao, SJ Kim, J Marchesan, KL Moss, L Jing, K Divaris, S Bencharit, CS Agler, T Morelli, S Zhang, L Sun, WT Seaman, D Cowley, SP Barros, JD Beck, M Munz, AS Schaefer, KE North
    Nat Commun, 2018-09-11;9(1):3686.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  112. Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice
    Authors: Z Cheng, L Wang, M Qu, H Liang, W Li, Y Li, L Deng, Z Zhang, GY Yang
    J Neuroinflammation, 2018-05-03;15(1):135.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  113. Reg3? is associated with cardiac inflammation and provides prognostic information in patients with acute coronary syndrome
    Authors: H Lörchner, C Widera, Y Hou, A Elsässer, H Warnecke, E Giannitsis, JS Hulot, T Braun, KC Wollert, J Pöling
    Int. J. Cardiol., 2018-05-01;258(0):7-13.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  114. Cell-penetrating interactomic inhibition of nuclear factor-kappa B in a mouse model of postoperative cognitive dysfunction
    Authors: SY Cheon, JM Kim, EH Kam, CC Ho, EJ Kim, S Chung, JH Jeong, DD Lee, SW Lee, BN Koo
    Sci Rep, 2017-10-18;7(1):13482.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  115. Topical Fibronectin Improves Wound Healing of Irradiated Skin
    Authors: MB Johnson, B Pang, DJ Gardner, S Niknam-Ben, V Soundaraja, A Bramos, DP Perrault, K Banks, GK Lee, RY Baker, GH Kim, S Lee, Y Chai, M Chen, W Li, L Kwong, YK Hong, AK Wong
    Sci Rep, 2017-06-20;7(1):3876.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  116. The blood-borne sialyltransferase ST6Gal-1 is a negative systemic regulator of granulopoiesis
    Authors: CWL Dougher, A Buffone, MJ Nemeth, M Nasirikena, EE Irons, PN Bogner, JTY Lau
    J. Leukoc. Biol., 2017-05-26;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  117. Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation
    Authors: M Toussaint, DJ Jackson, D Swieboda, A Guedán, TD Tsouroukts, YM Ching, C Radermecke, H Makrinioti, J Aniscenko, MR Edwards, R Solari, F Farnir, V Papayannop, F Bureau, T Marichal, SL Johnston
    Nat. Med., 2017-05-01;23(6):681-691.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  118. Obesity promotes prolonged ovalbumin-induced airway inflammation modulating Th1, Th2 and Th17 immune responses in BALB/c mice
    Authors: FM Silva, EE Oliveira, AC Gouveia, AS Brugiolo, CC Alves, JO Correa, J Gameiro, J Mattes, HC Teixeira, AP Ferreira
    Clin. Exp. Immunol, 2017-03-31;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  119. Swimming Motility Mediates the Formation of Neutrophil Extracellular Traps Induced by Flagellated Pseudomonas aeruginosa
    PLoS Pathog., 2016-11-17;12(11):e1005987.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  120. PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model
    Authors: Luise Erpenbeck
    Biol. Reprod, 2016-11-09;95(6):132.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  121. Beneficial Effects of Sodium Phenylbutyrate Administration During Infection with Salmonella enterica serovar Typhimurium
    Infect Immun, 2016-08-19;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  122. Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition
    PLoS Pathog, 2016-05-25;12(5):e1005644.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  123. Rhadinovirus host entry by co-operative infection.
    Authors: Lawler C, Milho R, May J, Stevenson P
    PLoS Pathog, 2015-03-19;11(3):e1004761.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  124. Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking beta-glucans.
    PLoS ONE, 2015-03-18;10(3):e0119244.
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  125. Lactobacillus rhamnosus GG and Bifidobacterium longum attenuate lung injury and inflammatory response in experimental sepsis.
    Authors: Khailova L, Petrie B, Baird C, Dominguez Rieg J, Wischmeyer P
    PLoS ONE, 2014-05-15;9(5):e97861.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  126. The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria.
    Authors: Behnsen J, Jellbauer S, Wong C, Edwards R, George M, Ouyang W, Raffatellu M
    Immunity, 2014-02-06;40(2):262-73.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  127. IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice.
    Authors: Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, Braun H, Lima-Junior R, Ribeiro R, Cunha F, Teixeira M, Beyaert R, Graham G, Liew F
    Mucosal Immunol, 2014-01-15;7(5):1079-93.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  128. Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.
    Authors: Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, Vidic J, Descamps D, Sallenave JM, Rauch M, Samson M, Delmas B
    PLoS Pathog., 2011-08-25;7(8):e1002202.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  129. Tissue inhibitor of metalloproteinases 3 regulates resolution of inflammation following acute lung injury.
    Authors: Gill SE, Huizar I, Bench EM
    Am. J. Pathol., 2009-12-11;176(1):64-73.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: ELISA Development
  130. Murine scald models characterize the role of neutrophils and neutrophil extracellular traps in severe burns
    Authors: Julia Elrod, Moritz Lenz, Antonia Kiwit, Lina Armbrust, Lavinia Schönfeld, Konrad Reinshagen et al.
    Frontiers in Immunology
  131. Senescence rewires microenvironment sensing to facilitate anti-tumor immunity
    Authors: Hsuan-An Chen, Yu-Jui Ho, Riccardo Mezzadra, Jose M. Adrover, Ryan Smolkin, Changyu Zhu et al.
    Cancer Discovery
  132. Neutrophil depletion enhanced the Clostridium novyi-NT therapy in mouse and rabbit tumor models
    Authors: Verena Staedtke, Tyler Gray-Bethke, Guanshu Liu, Eleni Liapi, Gregory J Riggins, Ren-Yuan Bai
    Neuro-Oncology Advances
  133. Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis
    Authors: Ludwig T. Weckbach, Ulrich Grabmaier, Andreas Uhl, Sebastian Gess, Felicitas Boehm, Annette Zehrer et al.
    Journal of Experimental Medicine
  134. Unique Angiogenesis From Cardiac Arterioles During Pericardial Adhesion Formation
    Authors: Kenji Namiguchi, Tomohisa Sakaue, Mikio Okazaki, Kaho Kanno, Yuhei Komoda, Fumiaki Shikata et al.
    Frontiers in Cardiovascular Medicine
  135. Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice
    Authors: Dániel Kucsera, Viktória E. Tóth, Dorottya Gergő, Imre Vörös, Zsófia Onódi, Anikó Görbe et al.
    Frontiers in Physiology
  136. Inhibition of myeloperoxidase enhances immune checkpoint therapy for melanoma
    Authors: Tracy W Liu, Seth T Gammon, Ping Yang, Wencai Ma, Jing Wang, David Piwnica-Worms
    Journal for ImmunoTherapy of Cancer
  137. Neutrophils and neutrophil serine proteases are increased in the spleens of estrogen-treated C57BL/6 mice and several strains of spontaneous lupus-prone mice
    Authors: Rujuan Dai, Catharine Cowan, Bettina Heid, Deena Khan, Zhihong Liang, Christine T. N. Pham et al.
    PLOS ONE
  138. A Chitin-Like Component on Sclerotic Cells of Fonsecaea pedrosoi Inhibits Dectin-1-Mediated Murine Th17 Development by Masking beta -Glucans
    Authors: Bilin Dong, Dongsheng Li, Ruoyu Li, Sharon C.-A. Chen, Weihuang Liu, Wei Liu et al.
    PLoS ONE
  139. Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19
    Authors: Coraline Radermecker, Nancy Detrembleur, Julien Guiot, Etienne Cavalier, Monique Henket, Céline d’Emal et al.
    Journal of Experimental Medicine
  140. Neutrophil extracellular traps promote liver micrometastasis in pancreatic ductal adenocarcinoma via the activation of cancer‑associated fibroblasts
    Authors: Shin Takesue, Kenoki Ohuchida, Tomohiko Shinkawa, Yoshiki Otsubo, Sokichi Matsumoto, Akiko Sagara et al.
    International Journal of Oncology
  141. In Silico Sperm Proteome Analysis to Investigate DNA Repair Mechanisms in Varicocele Patients
    Authors: Renata Finelli, Sara Darbandi, Peter Natesan Pushparaj, Ralf Henkel, Edmund Ko, Ashok Agarwal
    Front Endocrinol (Lausanne)
  142. Interleukin-17E, inducible nitric oxide synthase and arginase1 as new biomarkers in the identification of neutrophilic dermatoses
    Authors: R. Stalder, N. Brembilla, C. Conrad, N. Yawalkar, A. Navarini, W H Boehncke et al.
    Clin Exp Dermatol
  143. Functional proteomic profiling links deficient DNA clearance with increased mortality in individuals with severe COVID-19 pneumonia
    Authors: Iker Valle Aramburu, Dennis Hoving, Spyros I. Vernardis, Martha C.F. Tin, Marianna Ioannou, Mia I. Temkin et al.
    Immunity
  144. PDX Models: A Versatile Tool for Studying the Role of Myeloid-Derived Suppressor Cells in Breast Cancer
    Authors: Morten F. Gjerstorff, Sofie Traynor, Odd L. Gammelgaard, Simone Johansen, Christina B. Pedersen, Henrik J. Ditzel et al.
    Cancers (Basel)
  145. Astrocyte-derived microparticles initiate a neuroinflammatory cycle due to carbon monoxide poisoning
    Authors: Ruhela D, Bhopale VM, Kalakonda S et al.
    Brain Behav Immun Health
  146. Role of the Yersinia pestis Ail Protein in Preventing a Protective Polymorphonuclear Leukocyte Response during Bubonic Plague
    Authors: B. Joseph Hinnebusch, Clayton O. Jarrett, Julie A. Callison, Donald Gardner, Susan K. Buchanan, Gregory V. Plano
    Infection and Immunity
  147. Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons.
    Authors: Wong R, Lenart N, Hill L et al.
    Flow Cytometry Basics for the Non-Expert.
  148. RNase A Treatment Interferes With Leukocyte Recruitment, Neutrophil Extracellular Trap Formation, and Angiogenesis in Ischemic Muscle Tissue
    Authors: Manuel Lasch, Konda Kumaraswami, Simona Nasiscionyte, Susanna Kircher, Dominic van den Heuvel, Sarah Meister et al.
    Frontiers in Physiology
  149. Investigation of Neutrophil Extracellular Traps as Potential Mediators in the Pathogenesis of Non-Acute Subdural Hematomas: A Pilot Study
    Authors: Michael T. Bounajem, Frederik Denorme, John L. Rustad, Robert A. Campbell, Ramesh Grandhi
    Diagnostics (Basel)
  150. Immunodetection of NETs in Paraffin-Embedded Tissue
    Authors: Volker Brinkmann, Ulrike Abu Abed, Christian Goosmann, Arturo Zychlinsky
    Frontiers in Immunology
  151. A prospective marker for the prediction of postoperative deep venous thrombosis: Neutrophil extracellular traps
    Authors: Yin Li, Qinyi Jiang, Xiaohua Zhou, Mengyuan Wu, Jian Chen, Hao Liu et al.
    Frontiers in Cell and Developmental Biology
  152. The Importance of Hypoxia-Inducible Factors (HIF-1 and HIF-2) for the Pathophysiology of Inflammatory Bowel Disease.
    Authors: Kerber, E L, Padberg, C Et al.
    Int J Mol Sci
  153. Functional Blockage of S100A8/A9 Ameliorates Ischemia–Reperfusion Injury in the Lung
    Authors: Kentaro Nakata, Mikio Okazaki, Tomohisa Sakaue, Rie Kinoshita, Yuhei Komoda, Dai Shimizu et al.
    Bioengineering (Basel)
  154. Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome
    Authors: Julien Stackowicz, Nicolas Gaudenzio, Nadine Serhan, Eva Conde, Ophélie Godon, Thomas Marichal et al.
    Journal of Experimental Medicine
  155. Impact of C57BL/6J and SV-129 Mouse Strain Differences on Ischemia-Induced Postnatal Angiogenesis and the Associated Leukocyte Infiltration in a Murine Hindlimb Model of Ischemia
    Authors: Matthias Kübler, Philipp Götz, Anna Braumandl, Sebastian Beck, Hellen Ishikawa-Ankerhold, Elisabeth Deindl
    International Journal of Molecular Sciences
  156. Neutrophils delay repair process in Wallerian degeneration by releasing NETs outside the parenchyma
    Authors: Yamamoto Y, Kadoya K, Terkawi MA et al.
    Life science alliance
  157. Discovery of 1-((6-Aminopyridin-3-yl)Methyl)-3-(4-Bromophenyl)Urea as a Potent, Irreversible Myeloperoxidase Inhibitor
    Authors: Martin L. Marro, Andrew W. Patterson, Lac Lee, Lin Deng, Aimee Reynolds, Xianglin Ren et al.
    Journal of Pharmacology and Experimental Therapeutics
  158. Neutrophil inhibition improves acute inflammation in a murine model of viral myocarditis
    Authors: Paolo Carai, Laura Florit Florit González, Stijn Van Bruggen, Valerie Spalart, Daria De Giorgio, Nadéche Geuens et al.
    Cardiovascular Research
  159. Curcumin Ameliorates Particulate Matter-Induced Pulmonary Injury through Bimodal Regulation of Macrophage Inflammation via NF-kappa B and Nrf2
    Authors: Min Kook Lee, Hyo Dam Kim, Suk Hee Lee, Jin Hyup Lee
    International Journal of Molecular Sciences
  160. Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer
    Authors: Oxana Dmitrieva-Posocco, Amiran Dzutsev, David F. Posocco, Vivianty Hou, Wuxing Yuan, Vishal Thovarai et al.
    Immunity
  161. Fc gamma Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita
    Authors: Balint Kovacs, Jenny Tillmann, Lisa-Christin Freund, Falk Nimmerjahn, Christian D. Sadik, Katja Bieber et al.
    Frontiers in Immunology
  162. Age-associated pro-inflammatory adaptations of the mouse thoracic aorta
    Authors: Bianca Hemmeryckx, Marc F. Hoylaerts, Eveline Deloose, Cor E. Van Hove, Paul Fransen, Hidde Bult et al.
    Thrombosis and Haemostasis
  163. Enhancing Techniques for Determining Inflammatory Edema Formation and Neutrophil Accumulation in Murine Skin
    Authors: Ali A. Zarban, Hiba Chaudhry, Davide Maselli, Xenia Kodji, Joao de Sousa Valente, Justin Joachim et al.
    JID Innovations
  164. Tlr2/4‐Mediated Hyperinflammation Promotes Cherubism‐Like Jawbone Expansion in Sh3bp2 (P416R) Knockin Mice
    Authors: Yasuyuki Fujii, Nelson Monteiro, Shyam Kishor Sah, Homan Javaheri, Yasuyoshi Ueki, Zhichao Fan et al.
    JBMR Plus
  165. Early and Sustained Increases in Leukotriene B4 Levels Are Associated with Poor Clinical Outcome in Ischemic Stroke Patients
    Authors: Su Jing Chan, Mary P. E. Ng, Hui Zhao, Geelyn J. L. Ng, Chuan De Foo, Peter T.-H. Wong et al.
    Neurotherapeutics

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Human/Mouse Myeloperoxidase/MPO Antibody
By Anonymous on 01/24/2023
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Spleen tissue Species: Mouse
Immunocytochemistry/Immunofluorescence Human/Mouse Myeloperoxidase/MPO Antibody AF3667
Human/Mouse Myeloperoxidase/MPO Antibody
By Anonymous on 06/27/2021
Application: IHC Sample Tested: Epithelium Species: Mouse
Immunohistochemistry Human/Mouse Myeloperoxidase/MPO Antibody AF3667
Human/Mouse Myeloperoxidase/MPO Antibody
By Anonymous on 07/27/2019
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Peritoneal macrophages Species: Mouse

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Immunocytochemistry/Immunofluorescence Human/Mouse Myeloperoxidase/MPO Antibody AF3667
Human/Mouse Myeloperoxidase/MPO Antibody
By Anonymous on 09/30/2018
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Bone marrow cells Species: Mouse
Immunocytochemistry/Immunofluorescence Human/Mouse Myeloperoxidase/MPO Antibody AF3667