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Human/Mouse/Rat GRIN1/NMDAR1 Antibody

Catalog #: PPS011B
3 Citations Datasheet / COA / SDS
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PPS011B
Product Details
Citations (3)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse/Rat GRIN1/NMDAR1 Antibody Summary

Species Reactivity
Human, Mouse, Rat
Source
Monoclonal Mouse IgG Clone # R1JHL
Formulation
Lyophilized from cell culture media
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
Please refer to the PDF datasheet for specifications.
Immunoprecipitation
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: GRIN1/NMDAR1

NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.

Long Name
Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate, Subunit 1
Entrez Gene IDs
2902 (Human); 14810 (Mouse); 24408 (Rat)
Alternate Names
GluN1; GRIN1; MRD8; NDHMSD; NDHMSR;NMD-R1; NMDA R, NR1 Subunit; NMDA1; NMDAR1; NMD-R1; NR1

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Citations for Human/Mouse/Rat GRIN1/NMDAR1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. Synaptic scaling of corticostriatal circuits underlies hyperactivity in GABA Transporter-1 deficient mice
    Authors: Yan-Jiao Wu, Xin Yi, Xue Gu, Qi Wang, Qin Jiang, Ying Li et al.
    iScience
  2. The acid-sensing ion channel ASIC1a mediates striatal synapse remodeling and procedural motor learning
    Authors: Zhe Yu, Yan-Jiao Wu, Yi-Zhi Wang, Di-Shi Liu, Xing-Lei Song, Qin Jiang et al.
    Science Signaling
  3. ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion
    Nat Commun, 2016-12-07;7(0):13770.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot

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