Human/Mouse STAT4 Antibody

Catalog #: PAF-ST4
1 Citation Datasheet / COA / SDS

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PAF-ST4

All STAT4 Antibodies

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Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse STAT4 Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects human and mouse STAT4. No cross-reactivity with the other STATs has been detected by immunoprecipitation or by Western blotting.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse STAT4 synthetic peptide
aa 675-749

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.2 µg/mL

Human peripheral blood lymphocytes

Immunoprecipitation

1 µg/10⁶ cells

Human peripheral blood lymphocytes, see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Sterile PBS to a final concentration of 0.2 mg/mL.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: STAT4

Signal transduction and activator of transcription 4 (STAT4) is a member of the Jak/STAT signal transduction pathway. STAT4 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, homo or heterodimerizes with other STAT proteins, which then translocate to the nucleus and activate transcription of specific genes. STAT4 is expressed in subset of tissues including spleen, heart, brain, peripheral blood cells and testis. STAT4 is involved in mediating IL-12 response in lymphocytes and regulating T helper cell differentiation.

Long Name

Signal Transducer and Activator of Transcription 4

Entrez Gene IDs

6775 (Human); 20849 (Mouse)

Alternate Names

signal transducer and activator of transcription 4; SLEB11; STAT4

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Human/Mouse STAT4 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Leukemia inhibitory factor is linked to regulatory transplantation tolerance.
Authors: Metcalfe SM, Watson TJ, Shurey S, Adams E, Green CJ
Transplantation, 2005-03-27;79(6):726-30.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot