Human NRL Biotinylated Antibody

Catalog # Availability Size / Price Qty
BAF2945
Product Details
Citations (2)
FAQs
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Human NRL Biotinylated Antibody Summary

Species Reactivity
Human
Specificity
Detects human NRL in Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human NRL
Met1-Leu237
Accession # P54845
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human NRL

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: NRL

NRL is a 30 kDa nuclear transcription factor that belongs to the Maf subfamily within the bZIP (basic motif-leucine zipper) transcription factor family. It contains an N‑terminal transcriptional activation domain and a C-terminal DNA-binding bZIP domain that is also involved in homo- or heterodimerization. NRL regulates the expression of rod-specific genes and is expressed specifically in rod photoreceptors. NRL is phosphorylated at multiple sites, which likely regulates its activity. The amino acid sequence of human NRL is 92%, 94%, 90% and 90% identical to that of bovine, canine, rat and mouse NRL, respectively.

Long Name
Neural Retina-specific Leucine Zipper Protein
Entrez Gene IDs
4901 (Human)
Alternate Names
D14S46Eneural retina-specific leucine zipper protein; neural retina leucine zipper; NRL; NRL-MAF; RP27; RP27neural retinal-specific leucine zipper

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Citations for Human NRL Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness
    Sci Rep, 2016-07-29;6(0):30742.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  2. North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13
    Authors: Kent W. Small, Adam P. DeLuca, S. Scott Whitmore, Thomas Rosenberg, Rosemary Silva-Garcia, Nitin Udar et al.
    Ophthalmology

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