Human P2Y1/P2RY1 PE-conjugated Antibody

Name: Human P2Y1/P2RY1 PE-conjugated Antibody
Brand: R&D Systems
SKU: FAB9290P
Price: 349 USD

Catalog #: FAB9290P Datasheet / COA / SDS

Discontinued Product

FAB9290P has been discontinued.

View all P2Y1/P2RY1 products.

Detection of P2Y1/P2RY1 in HEK293 Human Cell Line Transfected with Human P2Y1/P2RY1 and eGFP by Flow Cytometry.

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Human P2Y1/P2RY1 PE-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Stains human P2Y1/P2RY1 transfectants but not irrelevant transfectants in flow cytometry.

Source

Monoclonal Mouse IgG_2A Clone # 479509

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

HEK293 human cell line transfected with human P2Y1/P2RY1
Accession # NP_002554

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of P2Y1/P2RY1 in HEK293 Human Cell Line Transfected with Human P2Y1/P2RY1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human P2Y1/P2RY1 and eGFP were stained with (A) Mouse Anti-Human P2Y1/P2RY1 PE-conjugated Monoclonal Antibody (Catalog # FAB9290P) or (B) isotype control antibody (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: P2Y1/P2RY1

P2RY1 belongs to the family of G protein-coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. P2RY1 functions as a receptor for extracellular ATP and ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C. ADP binding also may lead to a change in platelet shape and possible platelet aggregation.

Long Name

P2Y Purinergic Receptor 1

Entrez Gene IDs

5028 (Human); 18441 (Mouse); 25265 (Rat)

Alternate Names

ATP receptor; P2 purinoceptor subtype Y1; P2RY1; P2Y purinoceptor 1; P2Y1; P2Y1platelet ADP receptor; purinergic receptor P2Y, G-protein coupled, 1; Purinergic receptor