Human PA2G4 Antibody

Catalog #: AF3189 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3189
AF3189-SP

All PA2G4 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PA2G4 Antibody Summary

Species Reactivity

Human

Specificity

Detects human PA2G4 in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human PA2G4
Ser2-Asp394
Accession # Q9UQ80

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human PA2G4

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: PA2G4

The human PA2G4 gene encodes an intracellular protein that was also identified as Ebp 1 (ErbB3 binding protein 1). It has effects on cell cycle progression and inhibits proliferation when ectopically expressed in non-immortalized fibroblasts as well as breast cancer and prostate cancer cell lines. PA2G4 shares 56% amino acid similarity with a 42 kDa protein in the fission yeast, Schizosaccharomyces pombe, suggesting a high degree of evolutionary conservation.

Long Name

Proliferation-Associated 2G4

Entrez Gene IDs

5036 (Human); 18813 (Mouse); 288778 (Rat)

Alternate Names

Cell cycle protein p38-2G4 homolog; EBP1; ErbB-3 binding protein 1; ErbB3-binding protein 1; ErbB3-binding protein Ebp1; HG4-1; p38-2G4; PA2G4; proliferation-associated 2G4, 38kD; proliferation-associated 2G4, 38kDa; proliferation-associated protein 2G4