Human PGLYRP4/PGRP-I beta Antibody

Catalog #: MAB3018 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB3018
MAB3018-SP

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PGLYRP4/PGRP-I beta Antibody Summary

Species Reactivity

Human

Specificity

Detects human PGLYRP4/PGRP-I beta in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse PGRP-I beta or recombinant human PGRP-S is observed.

Source

Monoclonal Mouse IgG_2B Clone # 474034

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant human PGLYRP4/PGRP-I beta
Asp18-His373
Accession # Q96LB8

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human PGLYRP4/PGRP-I beta

Immunoprecipitation

25 µg/mL

Conditioned cell culture medium spiked with Recombinant Human PGLYRP4/PGRP-I beta, see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: PGLYRP4/PGRP-I beta

Peptidoglycan recognition protein intermediate beta (PGRP-I beta ), also known as peptidoglycan recognition protein 4 (PGLRP4), belongs to the family of human recognition molecules that bind peptidoglycan (a ubiquitous component of bacterial cell walls) and gram-positive bacteria as part of the innate immune response. It has N-acetylmuramoyl-L-alanine amidase activity and is primarily expressed in the esophagus, where it is thought to play a role in host antimicrobial defense. PGRP-I beta has two predicted transmembrane domains and extracellular N- and C-termini. The amino acid sequence of human PGRP- I beta is 99% and 76% identical to that of chimpanzee and mouse.

Long Name

Peptidoglycan Recognition Protein Intermediate, Beta/Peptidoglycan Recognition Protein 4

Entrez Gene IDs

57115 (Human)

Alternate Names

peptidoglycan recognition protein 4; peptidoglycan recognition protein I beta; Pglyrp-1 beta; PGLYRP4; PGRPI beta; PGRP-I beta; PGRP-I-beta