Human PRG-1/LPPR4 Antibody

Catalog #: MAB2874
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB2874
MAB2874-SP

All PRG-1/LPPR4 Antibodies

Product Details

Citations (1)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PRG-1/LPPR4 Antibody Summary

Species Reactivity

Human

Specificity

Detects PRG‑1/LPPR4 in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG_2B Clone # 368701

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

E. coli-derived recombinant human PRG‑1/LPPR4
Ser285-Asp715
Accession # AAO85400

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human PRG‑1/LPPR4

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: PRG-1/LPPR4

PRG-1 (plasticity-related gene-1) is a member of the lipid phosphate phosphatase-related protein (LPR) family. The 715 aa protein has a calculated (unglycosylated) molecular weight of 78 kDa. LPR members have six N-terminal transmembrane sequences and a C-terminal cytoplasmic domain thought to regulate phospholipid phosphatase activity. PRG-1 is expressed on axons in the hippocampus and is upregulated during axonal outgrowth. The C-terminal domain of human PRG-1 (amino acids 285‑715) shares 95% and 94% amino acid identity with mouse and rat PRG-1, respectively.

Long Name

Plasticity Related Gene 1/Lipid Phosphate Phosphatase-related Protein Type 4

Entrez Gene IDs

9890 (Human)

Alternate Names

LPPR4 lipid phosphate phosphatase-related protein type 4; LPPR4; LPR4; PHP1; PRG1; PRG-1; RP4-788L13.1

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Human PRG-1/LPPR4 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches
Authors: A Brosig, J Fuchs, F Ipek, C Kroon, S Schrötter, M Vadhvani, A Polyzou, J Ledderose, M van Diepen, HG Holzhütter, T Trimbuch, N Gimber, J Schmoranze, I Lieberam, C Rosenmund, C Spahn, P Scheerer, M Szczepek, G Leondariti, BJ Eickholt
Cell Rep, 2019-11-12;29(7):2028-2040.e8.
Species: Rat
Sample Types: Tissue Lysate
Applications: Western Blot