Human PTGDR (NP_000944) VersaClone cDNA

Catalog #: RDC0240 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
RDC0240

1 Image

View All Products for PTGDR

Product Details

Supplemental Products

Reviews

Summary Product Datasheets Data Images Background

Human PTGDR (NP_000944) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: PTGDR

PTGDR is a G protein-coupled receptor that has been shown to function as a prostanoid DP receptor. PTGDR is expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of PTGDR, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. Genetic variations in PTGDR are associated with susceptibility to asthma-related traits type 1 (ASRT1). Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea.

Long Name

Prostaglandin D2 Receptor

Entrez Gene IDs

5729 (Human); 19214 (Mouse); 498475 (Rat)

Alternate Names

AS1; ASRT1; DP; DP1; MGC49004; PGD receptor; PGD2 receptor; prostaglandin D2 receptor (DP); prostaglandin D2 receptor; Prostanoid DP receptor; PTGDR; PTGDR1