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Human RELM beta Antibody

Catalog #: MAB2917
3 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB2917
MAB2917-SP
Product Details
Citations (3)
FAQs
Supplemental Products
Reviews
Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human RELM beta Antibody Summary

Species Reactivity
Human
Specificity
Detects human RELM beta in direct ELISAs. Does not cross-react with recombinant mouse (rm) RELM alpha, rmRELM beta, recombinant rat RELM gamma, or rmResistin. Not recommended for natural lysates in Western blot.
Source
Monoclonal Mouse IgG1 Clone # 250911
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human RELM beta
Gly21-Thr111
Accession # Q9BQ08
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
ELISA
Detects human RELM beta in direct ELISAs.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: RELM beta

Resistin-like molecule beta (RELM beta, also known as Found in Inflammatory Zone 2 (FIZZ2), is a homodimeric protein belonging to the RELM/FIZZ family of cysteine rich secretory proteins. RELM beta secretion by intestinal goblet cells is induced by Th2 cytokines in response to nematode infections.

Long Name
Resistin-like Molecule beta
Entrez Gene IDs
84666 (Human); 57263 (Mouse)
Alternate Names
C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 2; CCRG; Colon and small intestine-specific cysteine-rich protein; Colon carcinoma-related gene protein; cysteine-rich secreted A12-alpha-like protein 1; Cysteine-rich secreted protein A12-alpha-like 1; Cysteine-rich secreted protein FIZZ2; FIZZ1; FIZZ2RELM-beta; found in inflammatory zone 1; HXCP2XCP2; RELM beta; RELMb; RELMbeta; resistin like beta; resistin-like beta; RETNL2

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Citations for Human RELM beta Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. Aryl hydrocarbon receptor ligands enhance lung immunity through intestinal IKK β pathways
    Authors: TB Tsay, PH Chen, LW Chen
    J Transl Med, 2019-09-05;17(1):304.
    Species: Mouse
    Sample Types: Protein
    Applications: Western Blot
  2. Toll-like receptor stimulation induces nondefensin protein expression and reverses antibiotic-induced gut defense impairment.
    Authors: Wu Y, Hsu C, Chen P, Fung C, Chen L
    Infect Immun, 2014-03-04;82(5):1994-2005.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  3. Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension.
    Authors: Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Teng X, Hassoun PM, Yang SC, Champion HC, Tuder RM, Johns RA
    Am. J. Respir. Cell Mol. Biol., 2009-02-27;41(5):553-61.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: Western Blot

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