Human SorCS1 (NP_443150) VersaClone cDNA

Catalog #: RDC2962 Datasheet / COA / SDS

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RDC2962

Human SorCS1 (NP_443150) VersaClone cDNA

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Human SorCS1 (NP_443150) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: SorCS1

SorCS proteins are members of the Vps10p (vacuolar protein-sorting 10 protein) family of sorting receptors. They are synthesized as proforms that undergo proteolytic processing to generate mature type I transmembrane receptors. The extracellular domains (ECD) show an imperfect LRR plus a Vps10p domain. The SorCS1 Vps10p domain binds both PDGF-BB and NGF-propeptide, while the SorCS3 Vps10p domain binds both pro- and mature NGF.

Long Name

Sortilin-related VPS10 Domain Containing Receptor 1

Entrez Gene IDs

114815 (Human); 58178 (Mouse); 309533 (Rat)

Alternate Names

FLJ41758; FLJ43475; FLJ44957; hSorCS; SORCS receptor 1; SORCS; SorCS1; sortilin-related VPS10 domain containing receptor 1; VPS10 domain receptor protein SORCS 1; VPS10 domain receptor SorCS; VPS10 domain-containing receptor SorCS1