Human SOX15 Biotinylated Antibody

Catalog #: BAF4070 Datasheet / COA / SDS

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BAF4070

All SOX15 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human SOX15 Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human SOX15 in Western blots. In Western blots, less than 5% cross-reactivity with recombinant human (rh) SOX1, 5, 6, 7, 9, 13, and 17 is observed.

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human SOX15
Met1-Leu233
Accession # O60248

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human SOX15

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SOX15

SOX15 (also known as SOX20) is a nuclear, 25 kDa transcriptional repressor that belongs to group G of the SOX gene family. Human SOX15 is 233 amino acids (aa) in length and contains a 63 aa DNA-binding HMG-box (amino acids 48‑110). Although the C-terminus (aa 126‑233) does not bind DNA, it is required for SOX15 repressive activity. It may accomplish this by interacting with beta -catenin. SOX15 is expressed in myoblasts and regulates skeletal muscle regeneration and differentiation. Human SOX15 shares 75% aa sequence identity with mouse SOX15.

Long Name

Transcription Factor SOX15

Entrez Gene IDs

6665 (Human); 20670 (Mouse); 363632 (Rat)

Alternate Names

protein SOX-15; SOX15; SOX20; SOX20Protein SOX-20; SOX26; SOX26SOX12; SOX27; SOX27Protein SOX-12; SRY (sex determining region Y)-box 15; SRY (sex determining region Y)-box 20