Human TMEM18 (NP_690047) VersaClone cDNA

Catalog #: RDC0226 Datasheet / COA / SDS

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Human TMEM18 (NP_690047) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: TMEM18

TMEM18 is an obesity risk gene. It is a small protein of 140 residues and is predicted to be mostly alpha-helical with three transmembrane parts. TMEM18 forms homooligomers, independently of the DNA-binding domain. TMEM18 localizes to the nuclear membrane and binds to DNA in a sequence-specific manner. TMEM18 is a transcription repressor sequence-specific ssDNA and dsDNA binding protein with preference for GCT end CTG repeats. TMEM18 is a cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC).

Long Name

Transmembrane Protein 18

Entrez Gene IDs

129787 (Human); 211986 (Mouse); 362722 (Rat)

Alternate Names

TMEM18; transmembrane protein 18