Human UNC5H4 (NP_543148) VersaClone cDNA

Catalog #: RDC2136 Datasheet / COA / SDS

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RDC2136

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Human UNC5H4 (NP_543148) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: UNC5H4

Members of the UNC5H family are best known as receptors for the axon guidance molecule netrin. Structurally, UNC5Hs have two Ig and two thrombospondin type 1 domains in their extracellular region, and a conserved ZU-5 domain, a deleted in colorectal cancer (DCC)-binding domain, and a C-terminal death domain in their cytoplasmic region. In general, they mediate the chemorepulsive effects of netrin, while the other netrin receptor subtype, DCC, mediates attraction. Members of the UNC5H family have also been implicated as tumor suppressors and regulators of apoptosis.

Long Name

Netrin Receptor UNC5D

Entrez Gene IDs

137970 (Human)

Alternate Names

FLJ16019; KIAA1777Unc5h4; netrin receptor UNC5D; netrin receptor Unc5h4; PRO34692; Protein unc-5 homolog 4; Protein unc-5 homolog D; unc-5 homolog 4; unc-5 homolog D (C. elegans); UNC5D; UNC5H4