Imiloxan hydrochloride
Chemical Name: 2-(1-Ethyl-2-indazoyl)methyl-1,4-benzodioxan hydrochloride
Purity: ≥98%
Biological Activity
Imiloxan hydrochloride is a moderately potent, but highly selective α2-adrenoceptor antagonist, the only reported selective antagonist at the α2B-adrenoceptor not having potent α1-adrenoceptor antagonist activity.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Assessment of imiloxan as a selective α2B-adrenoceptor antagonist.
Michel et al.
Br.J.Pharmacol., 1990;99:560 -
2-(2-Imidazolylmethyl)-1,4-benzodioxans, a series of selective alpha2-adrenoceptor antagonists.
Michel and Whiting
Br.J.Pharmacol., 1981;74:255P
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