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Irbesartan

Catalog #: 5798 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5798/50
Irbesartan | CAS No. 138402-11-6 | Angiotensin AT1 Receptor Antagonists
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Description: Potent AT1 antagonist

Chemical Name: 2-Butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one

Purity: ≥98%

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Biological Activity

Irbesartan is a potent angiotensin II type 1 receptor (AT1) antagonist (IC50 = 1.3 nM). Displays antihypertensive activity. Orally bioavailable.

Technical Data

M.Wt:
428.53
Formula:
C25H28N6O
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
138402-11-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Angiotensin II type 1 receptor blockers.
    Burnier et al.
    Circulation, 2001;103:904

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