Jedi2
Chemical Name: 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
Purity: ≥98%
Biological Activity
Jedi2 is a piezo1 channel activator. Promotes Ca2+ influx into HEK293 cells expressing Piezo1 channels. Elicits responses in mouse Piezo1-transfected, but not Piezo2-transfected cells.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel.
Wang et al.
Nat.Commun., 2018;9:1300
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Citation for Jedi2
The citations listed below are publications that use Tocris products. Selected citations for Jedi2 include:
1 Citation: Showing 1 - 1
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Selective Chemical Activation of Piezo1 in Leukemia Cell Membrane: Single Channel Analysis.
Authors: Yuri Et al.
Int J Mol Sci 2021;22
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