L-693,403 maleate

Catalog #: 0426 Datasheet / COA / SDS

Discontinued Product

0426 has been discontinued.
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L-693,403 maleate | CAS No. 207455-21-8 | General Sigma Receptor Ligands
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Description: High affinity σ ligand

Chemical Name: N-1'-Benzyl-3,4-dihydrospiro[1H-indene-1,4'-piperidine] maleate

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Biological Activity

L-693,403 maleate is a high affinity σ ligand with excellent selectivity over the dopamine D2 receptor.

Technical Data

M.Wt:
393.48
Formula:
C20H23N.C4H4O4
Solubility:
Soluble to 100 mM in DMSO
Storage:
Desiccate at -20°C
CAS No:
207455-21-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of Merck Sharp and Dohme Ltd.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Spiropiperidines as high affinity selective sigma ligands.
    Chambers et al.
    J.Med.Chem., 1992;35:2033

Product Datasheets

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