Home / Chemokine Receptor Agonists / LIH 383

LIH 383

Catalog #: 8095 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8095/1
LIH 383
1 Image
Description: Atypical chemokine receptor (ACKR3) agonist

Purity: ≥95%

Product Details
Reviews
Biological Activity Technical Data Additional Information Product Datasheets Calculators

Biological Activity

LIH 383 is a potent and highly selective atypical chemokine receptor (ACKR3/CXCR7) agonist. LIH 383 competes directly with CXCL12-AF647 and is more potent in inducing β-arrestin recruitment to ACKR3 (EC50 = 0.61 nM) than the full-length chemokine ligands CXCL12 or CXCL11 (EC50 values are 1.2 nM and 2.2 nM, respectively). In a rat ex vivo model, LIH 383 increases the availability and signaling of opioid peptides at classical receptors.

Technical Data

M.Wt:
997.23
Formula:
C45H72N16O8S
Sequence:
FGGFMRRK

(Modification: Lys-8 = C-terminal amide)

Solubility:
Soluble to 2 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2866266-58-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under patent license from Luxembourg Institute of Health.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

Reviews for LIH 383

There are currently no reviews for this product. Be the first to review LIH 383 and earn rewards!

Have you used LIH 383?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.