Loreclezole hydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Loreclezole inhibition of recombinant α1β1γ2L GABA_A receptor single channel currents.
   Fisher et al.
   Neuropharmacology, 2000;39:235
3. Loreclezole enhances apparent desensitisation of recombinant GABA_A receptor currents.
   Donnelly and Macdonald
   Neuropharmacology, 1996;35:1233
4. Compounds exhibiting selective efficacy for different β subunits of human recombinant γ-aminobutyric acid_A receptors.
   Smith et al.
   J.Pharmacol.Exp.Ther., 2004;311:601
5. Loreclezole as a simple functional marker for homomeric ρ type GABA_C receptors.
   Thomet et al.
   Eur.J.Pharmacol., 2000;408:R1

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