LUF 6283
Discontinued Product
Chemical Name: 5-Butyl-1H-pyrazole-3-carboxylic acid
Purity: ≥98%
Biological Activity
LUF 6283 is a partial agonist of hydroxycarboxylic acid receptor 2 (HCA2) (Ki = 0.55 μM). Thought to lower plasma very-low-density lipoprotein (VLDL)-triglyceride levels by affecting hepatic VLDL production in normolipidemic C57BL/6 mice.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Effects of pyrazole partial agonists on HCA2-mediated flushing and VLDL-triglyceride levels in mice.
Li et al.
Br.J.Pharmacol., 2012;167:818
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