LY 231617
Discontinued Product
Chemical Name: 2,6-bis(1,1-Dimethylethyl)-4-[(ethylamino)methyl]phenol hydrochloride
Purity: ≥98%
Biological Activity
LY 231617 is an antioxidant; protects against ischemia-induced neuronal damage in rat models of global and focal cerebral ischemia. Neuroprotective in vitro and in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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The antioxidant LY 231617 reduces global ischemic neuronal injury in rats.
Clemens et al.
Stroke, 1993;24:716 -
Characterization of LY 231617 protection against hydrogen peroxide toxicity.
Fuson et al.
J.Neurochem., 1999;72:1154 -
Neuroprotective effects of the antioxidant LY 231617 and NO synthase inhibitors in global ischaemia.
O'Neill et al.
Brain Res., 1997;760:170
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