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LY 310762 hydrochloride

Catalog #: 3078
1 Citation Datasheet / COA / SDS
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3078/10
3078/50
LY 310762 hydrochloride | CAS No. 192927-92-7 | 5-HT1D Receptor Antagonists
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Description: Selective 5-HT1D antagonist

Chemical Name: 1-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-one hydrochloride

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

LY 310762 hydrochloride is a 5-HT1D-preferring receptor antagonist (EC50 = 31 nM). Displays no activity on 5-HT transport.

Technical Data

M.Wt:
430.94
Formula:
C24H27FN2O2.HCl
Solubility:
Soluble to 10 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
192927-92-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from Eli Lilly and company

Background References

  1. The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig.
    Pullar et al.
    Eur.J.Pharmacol., 2004;493:85

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Citation for LY 310762 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for LY 310762 hydrochloride include:

1 Citation: Showing 1 - 1

  1. Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti.
    Authors: Conley Et al.
    Pain  2015;352:53

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