Mouse C1qR1/CD93 Antibody

Catalog #: AF1696
8 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF1696
AF1696-SP

All C1qR1/CD93 Antibodies

Product Details

Citations (8)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse C1qR1/CD93 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse C1q R1/CD93 in direct ELISAs and Western blots.

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse C1q R1/CD93
Ala23-Asn572
Accession # O89103

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse C1q R1/CD93

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: C1qR1/CD93

C1q R1, also known as C1q Rp, CD93, Cell Surface Antigen AA4 and lymphocyte antigen 68, is a type I transmembrane protein. It contains a C-type lectin family domain and five EGF-like domains in its extracellular region, as well as a tyrosine kinase-recognition motif in its cytoplasmic region. It is most abundantly expressed on endothelial cells and platelets and is also expressed in neutrophils, glial cells and monocytes. C1q R1 is a marker for early multipotent hematopoietic cells and may participate in C1q/MBL/SPA-mediated enhancement of phagocytic function by monocytes.

Long Name

Complement Component C1q Receptor

Entrez Gene IDs

22918 (Human); 17064 (Mouse); 84398 (Rat)

Alternate Names

AA4 Antigen; C1q R1; C1q receptor 1; C1q Rp; C1q/MBL/SPA receptor; C1qR(P); C1qR1; C1qRp; CD93 antigenC1qR; CD93 molecule; CD93; CDw93C1QR1; Collectin Receptor; Complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; Matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Mouse C1qR1/CD93 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

8 Citations: Showing 1 - 8
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A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state
Authors: Ghazal Zekavat, Raha Mozaffari, Vanessa J. Arias, Susan Y. Rostami, Armen Badkerhanian, Andrea J. Tenner et al.
Immunogenetics
Significance of Soluble CD93 in Type 2 Diabetes as a Biomarker for Diabetic Nephropathy: Integrated Results from Human and Rodent Studies
Authors: M Lee, HS Park, MY Choi, HZ Kim, SJ Moon, JY Ha, A Choi, YW Park, JS Park, EC Shin, CW Ahn, S Kang
J Clin Med, 2020-05-08;9(5):.
SOX4 promotes vascular abnormality in glioblastoma and is a novel target to improve drug delivery
Authors: Yao, K;Yang, M;Shu, M;Wang, T;Gao, D;Zhou, L;Wang, G;Zhang, Z;Tang, J;
Translational oncology
Species: Mouse
Sample Types: Whole Tissue
Applications: Immunohistochemistry
SproutAngio: an open-source bioimage informatics tool for quantitative analysis of sprouting angiogenesis and lumen space
Authors: Beter, M;Abdollahzadeh, A;Pulkkinen, HH;Huang, H;Orsenigo, F;Magnusson, PU;Yl�-Herttuala, S;Tohka, J;Laakkonen, JP;
Scientific reports
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC
CD93 promotes ?1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis
Authors: R Lugano, K Vemuri, D Yu, M Bergqvist, A Smits, M Essand, S Johansson, E Dejana, A Dimberg
J. Clin. Invest., 2018-06-25;128(8):3280-3297.
Species: Human, Mouse
Sample Types: Whole Tissue
Applications: IHC
Membrane-associated CD93 regulates leukocyte migration and C1q-hemolytic activity during murine peritonitis.
Authors: Greenlee-Wacker MC, Briseno C, Galvan M, Moriel G, Velazquez P, Bohlson SS
J. Immunol., 2011-08-17;187(6):3353-61.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
Applications: ELISA Development
Discovery and validation of biomarkers that respond to treatment with brivanib alaninate, a small-molecule VEGFR-2/FGFR-1 antagonist.
Authors: Ayers M, Fargnoli J, Lewin A, Wu Q, Platero JS
Cancer Res., 2007-07-15;67(14):6899-906.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P
Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution
Authors: Fabrizio Orsenigo, Lei Liu Conze, Suvi Jauhiainen, Monica Corada, Francesca Lazzaroni, Matteo Malinverno et al.
eLife