Mouse CD59b Antibody

Catalog #: AF2650 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF2650
AF2650-SP

All CD59b Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse CD59b Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse CD59b in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse CD59b
Leu24-Asn104
Accession # P58019

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse CD59b

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CD59b

CD59, also known as membrane attack complex inhibition factor (MACIF), is a GPI-linked complement regulatory protein that prevents the formation of membrane attack complex and inhibits complement mediated lysis. In mouse, the gene encoding CD59 has been duplicated, giving rise to CD59a and CD59b. The two proteins are differentially expressed in tissues and share approximately 65% amino acid sequence identity.

Entrez Gene IDs

333883 (Mouse)

Alternate Names

16.3A5;1F5;CD59 glycoprotein;EJ16;EJ30;EL32;G344;HRF20;HRF-20;MACIF;MAC-IP;MEM43;MIC11;MIN1;MIN2;MIN3;MIRL;MSK21;p18-20; CD59b