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Mouse CXCR3 PE-conjugated Antibody

Catalog #: FAB1685P
12 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB1685P-025
FAB1685P-100
Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry.
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Product Details
Citations (12)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse CXCR3 PE-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse CXCR3.
Source
Monoclonal Rat IgG2A Clone # 220803
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
CHO Chinese hamster ovary cell line transfected with mouse CXCR3
Met1-Leu367
Accession # AAC40163
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of CXCR3 antibody in Mouse Splenocytes antibody by Flow Cytometry. View Larger

Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 APC-conjugated Monoclonal Antibody (Catalog # FAB4841A) and either (A) Rat Anti-Mouse CXCR3 PE-conjugated Monoclonal Antibody (Catalog # FAB1685P) or (B) Rat IgG2APhycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CXCR3

CXCR3 is a G protein coupled chemokine receptor that binds the alpha chemokines MIG (CXCL9), IP-10 (CXCL10) and I-TAC (CXCL11). CXCR3 is expressed on activated T cells, B cells and NK cells.

Entrez Gene IDs
2833 (Human); 12766 (Mouse); 84475 (Rat)
Alternate Names
CD183 antigen; CD183; chemokine (C-X-C motif) receptor 3; chemokine (C-X-C) receptor 3; CKR-L2IP-10 receptor; CMKAR3; C-X-C chemokine receptor type 3; CXCR3; CXC-R3; CXCR-3; G protein-coupled receptor 9CD182; GPR9; GPR9Mig-R; Interferon-inducible protein 10 receptor; IP10 receptor; IP10-R; Mig receptor; MigR

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Citations for Mouse CXCR3 PE-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

12 Citations: Showing 1 - 10
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  1. Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells
    Authors: F Bian, Y Xiao, FL Barbosa, RG de Souza, H Hernandez, Z Yu, SC Pflugfelde, CS de Paiva
    Mucosal Immunol, 2019-01-29;12(4):897-908.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia.
    Authors: Arieta Kuksin C, Gonzalez-Perez G, Minter L
    Blood, 2015-02-03;125(13):2087-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation.
    Authors: Marks BR, Nowyhed HN, Choi JY, Poholek AC, Odegard JM, Flavell RA, Craft J
    Nat. Immunol., 2009-09-06;10(10):1125-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells.
    Authors: Karagiannis ED, Popel AS
    Proc. Natl. Acad. Sci. U.S.A., 2008-09-09;105(37):13775-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. Amelioration of delayed-type hypersensitivity responses by IL-27 administration.
    Authors: Miyazaki Y, Shimanoe Y, Wang S, Yoshida H
    Biochem. Biophys. Res. Commun., 2008-06-20;373(3):397-402.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  6. Both Th1 and Th17 are immunopathogenic but differ in other key biological activities.
    Authors: Cox CA, Shi G, Yin H, Vistica BP, Wawrousek EF, Chan CC, Gery I
    J. Immunol., 2008-06-01;180(11):7414-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  7. Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules.
    Authors: Calderon B, Suri A, Miller MJ
    Proc. Natl. Acad. Sci. U.S.A., 2008-04-21;105(16):6121-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  8. Expression of CXCL4 in microglia in vitro and in vivo and its possible signaling through CXCR3.
    Authors: de Jong EK, de Haas AH, Brouwer N, van Weering HR, Hensens M, Bechmann I, Pratley P, Wesseling E, Boddeke HW, Biber K
    J. Neurochem., 2008-02-01;105(5):1726-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  9. E- and P-selectins synergistically inhibit bleomycin-induced pulmonary fibrosis.
    Authors: Horikawa M, Fujimoto M, Hasegawa M, Matsushita T, Hamaguchi Y, Kawasuji A, Matsushita Y, Fujita T, Ogawa F, Takehara K, Steeber DA, Sato S
    Am. J. Pathol., 2006-09-01;169(3):740-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  10. CXCL10 is the key ligand for CXCR3 on CD8+ effector T cells involved in immune surveillance of the lymphocytic choriomeningitis virus-infected central nervous system.
    Authors: Christensen JE, de Lemos C, Moos T, Christensen JP, Thomsen AR
    J. Immunol., 2006-04-01;176(7):4235-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  11. CD8+ T cells in the central nervous system of mice with herpes simplex infection are highly activated and express high levels of CCR5 and CXCR3
    Authors: Liza Lind, Alexandra Svensson, Karolina Thörn, Malgorzata Krzyzowska, Kristina Eriksson
    Journal of NeuroVirology
  12. CXCR3 as a molecular target in breast cancer metastasis: inhibition of tumor cell migration and promotion of host anti-tumor immunity
    Authors: Guiquan Zhu, H. Hannah Yan, Yanli Pang, Jiang Jian, Bhagelu R. Achyut, Xinhua Liang et al.
    Oncotarget

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