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Mouse DCC (NP_031857) VersaClone cDNA

Catalog #: RDC2719 Datasheet / COA / SDS
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RDC2719
Mouse DCC (NP_031857) VersaClone cDNA
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Mouse DCC (NP_031857) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Mouse

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Product Datasheet
COA
SDS

Background: DCC

Deleted in colorectal cancer (DCC) encodes a typeI transmembrane glycoprotein that belongs to the immunoglobulin superfamily. Two forms of the protein (the long and short isoforms) are produced from the same gene by the use of alternative initiation sites. A third isoform that is produced by alternative splicing is expressed only in the embryo. The extracellular domain of mouse DCC shares 97% and 99% amino acid sequence identity with human and rat DCC extracellular domains, respectively. DCC is a receptor for the Netrin family axon guidance molecules. DCC functions primarily in axon attraction, but is also a coreceptor with UNC5 receptors for axon repulsion.

Long Name
Deleted in Colorectal Cancer
Entrez Gene IDs
1630 (Human); 13176 (Mouse)
Alternate Names
Colorectal cancer suppressor; CRC18; CRCR1; DCC; deleted in colorectal cancer protein; deleted in colorectal carcinoma; IGDCC1colorectal tumor suppressor; Immunoglobulin superfamily DCC subclass member 1; immunoglobulin superfamily, DCC subclass, member 1; netrin receptor DCC; Tumor suppressor protein DCC

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