Mouse IL-18 R beta /IL-1 R7 Antibody

Catalog #: AF199
2 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF199
AF199-SP

Product Details

Citations (2)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse IL-18 R beta /IL-1 R7 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse IL‑18 R beta /IL‑1 R7 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross‑reactivity with recombinant mouse IL-18 R is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse IL‑18 R beta /IL‑1 R7
Phe20-Glu356
Accession # Q9Z2B1

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse IL‑18 R beta /IL‑1 R7

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-18 R beta/IL-1 R7

IL-18 R beta, also referred to as Accessory Protein-like (AcPL), is a member of the IL-1 receptor superfamily and is designated IL-1 R7.

Long Name

Interleukin 18 Receptor beta

Entrez Gene IDs

8807 (Human); 16174 (Mouse)

Alternate Names

Accessory protein-like; AcPL; CD218 antigen-like family member B; CD218b antigen; CD218b; CDw218b; IL-1 R7; IL-18 R beta; IL-18 receptor accessory protein; IL-18 receptor beta; IL18R beta; IL-18RAcP; IL18RAP; IL18RB; IL-18Rb; IL-18Rbeta; IL-18R-beta; IL-1R accessory protein-like; IL1R7; IL-1R7; IL-1R-7; IL-1RAcPL; interleukin 18 receptor accessory protein; Interleukin-1 receptor 7; interleukin-18 receptor accessory protein; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta; MGC120589; MGC120590

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Mouse IL-18 R beta /IL-1 R7 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS
Authors: C Eitan, A Siany, E Barkan, T Olender, KR van Eijk, M Moisse, SMK Farhan, YM Danino, E Yanowski, H Marmor-Kol, N Rivkin, NS Yacovzada, ST Hung, J Cooper-Kno, CH Yu, C Louis, SL Masters, KP Kenna, RAA van der Sp, W Sproviero, A Al Khleifa, A Iacoangeli, A Shatunov, AR Jones, Y Elbaz-Alon, Y Cohen, E Chapnik, D Rothschild, O Weissbrod, G Beck, E Ainbinder, S Ben-Dor, S Werneburg, DP Schafer, RH Brown, PJ Shaw, P Van Damme, LH van den Be, H Phatnani, E Segal, JK Ichida, A Al-Chalabi, JH Veldink, Project Mi, NYGC ALS C, E Hornstein
Nature Neuroscience, 2022-03-31;25(4):433-445.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry
Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving ERK1/2-dependent NFATc4 phosphorylation.
Authors: Chandrasekar B, Patel DN, Mummidi S, Kim JW, Clark RA, Valente AJ
J. Biol. Chem., 2007-12-17;283(7):4200-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry