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Mouse IL-4 Quantikine ELISA Kit

Catalog #: M4000B
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Mouse IL-4 ELISA Standard Curve
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Summary Precision Recovery Linearity Data Examples Product Datasheets Preparation and Storage Background Related Research Areas

Mouse IL-4 Quantikine ELISA Kit Summary

Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (50 uL), Serum (50 uL)
Sensitivity
2 pg/mL
Assay Range
7.8 - 500 pg/mL (Cell Culture Supernates, Serum)
Specificity
Natural and recombinant mouse IL-4
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
Interference observed with 1 or more available related molecules.

Product Summary

The Quantikine Mouse IL-4 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse IL-4 levels in cell culture supernates and serum. It contains E. coli-expressed recombinant mouse IL-4 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse IL-4 accurately. Results obtained using natural mouse IL-4 showed dose curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-4.

Precision

Intra-Assay Precision (Precision within an assay)
Inter-Assay Precision (Precision between assays)

Cell Culture Supernates, Serum

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 20.1 58.6 199 20.7 58.8 203
Standard Deviation 1.3 1.8 8.9 1.2 2.7 10.6
CV% 6.5 3.1 4.5 5.8 4.6 5.2

Recovery

The recovery of mouse IL-4 spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=8) 95 84-109
Serum (n=7) 95 88-118

Linearity

To assess the linearity of the assay, five or more samples containing and/or spiked with various concentrations of mouse IL-4 in each matrix were diluted with Calibrator Diluent and then assayed.
Mouse IL-4 ELISA Linearity

Scientific Data

N/A Mouse IL-4 ELISA Standard Curve View Larger

Mouse IL-4 ELISA Standard Curve

Product Datasheets

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-4

IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R? and the common ? chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R? and IL-13 R?1. The type II receptor also transduces IL-13 mediated signals.

Long Name:
Interleukin 4
Entrez Gene IDs:
3565 (Human); 16189 (Mouse); 287287 (Rat); 397225 (Porcine); 280824 (Bovine); 403785 (Canine); 574281 (Primate); 100302454 (Rabbit)
Alternate Names:
B cell growth factor 1; BCDF; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; IL4; IL-4; IL-4B_cell stimulatory factor 1; IL4E12; interleukin 4; interleukin-4; Lymphocyte stimulatory factor 1; MGC79402; pitrakinra
&#9888; WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Citations for Mouse IL-4 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

164 Citations: Showing 1 - 10
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  1. Pseudoirreversible inhibition elicits persistent efficacy of a sphingosine 1-phosphate receptor 1 antagonist
    Authors: Maruyama, Y;Ohsawa, Y;Suzuki, T;Yamauchi, Y;Ohno, K;Inoue, H;Yamamoto, A;Hayashi, M;Okuhara, Y;Muramatsu, W;Namiki, K;Hagiwara, N;Miyauchi, M;Miyao, T;Ishikawa, T;Horie, K;Hayama, M;Akiyama, N;Hirokawa, T;Akiyama, T;
    Nature communications
    Species: Mouse
    Sample Types: Tissue Homogenates
  2. Helminth alleviates COVID-19-related cytokine storm in an IL-9-dependent way
    Authors: Cao, Z;Wang, J;Liu, X;Liu, Y;Li, F;Liu, M;Chiu, S;Jin, X;
    mBio
    Species: Mouse
    Sample Types: Serum
  3. SELENOK-dependent CD36 palmitoylation regulates microglial functions and A? phagocytosis
    Authors: Ouyang, P;Cai, Z;Peng, J;Lin, S;Chen, X;Chen, C;Feng, Z;Wang, L;Song, G;Zhang, Z;
    Redox biology
    Species: Mouse
    Sample Types: Bacteria
  4. STING signaling activation modulates macrophage polarization via CCL2 in radiation-induced lung injury
    Authors: Ni, J;Guo, T;Zhou, Y;Jiang, S;Zhang, L;Zhu, Z;
    Journal of translational medicine
    Species: Mouse
    Sample Types: BALF, Serum
  5. Fallopia japonica Root Extract Ameliorates Ovalbumin-Induced Airway Inflammation in a CARAS Mouse Model by Modulating the IL-33/TSLP/NF-?B Signaling Pathway
    Authors: Jin, J;Fan, YJ;Nguyen, TV;Yu, ZN;Song, CH;Lee, SY;Shin, HS;Chai, OH;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: BALF, NLF
  6. Tnpo3 controls splicing of the pre-mRNA encoding the canonical TCR ? chain of iNKT cells
    Authors: Iwanami, N;Richter, AS;Sikora, K;Boehm, T;
    Nature communications
    Species: Mouse
    Sample Types: Serum
  7. Antidiabetic and Immunoregulatory Activities of Extract of Phyllanthus emblica L. in NOD with Spontaneous and Cyclophosphamide-Accelerated Diabetic Mice
    Authors: Lin, CH;Kuo, YH;Shih, CC;
    International journal of molecular sciences
    Species: Mouse
    Sample Types:
  8. Schistosoma japonicum Tyrosine Hydroxylase is promising targets for immunodiagnosis and immunoprotection of Schistosomiasis japonica
    Authors: Piao, X;Duan, J;Jiang, N;Liu, S;Hou, N;Chen, Q;
    PLoS neglected tropical diseases
    Species: Mouse
    Sample Types: Serum
  9. Adjuvant effect of dendritic cells activator Imiquimod in genetic immunization with HIV-1 p55 Gag
    Authors: Alves, JM;Inyushin, M;Tsytsarev, V;Roldan-Kalil, JA;Miranda-Valentin, E;Maldonado-Martinez, G;Ramos-Feliciano, KM;Hunter-Mellado, R;
    Journal of immunological techniques in infectious diseases
    Species: Mouse
    Sample Types: Cell Culture Supernates
  10. Eosinophil-derived IL-4 is necessary to establish the inflammatory structure in innate inflammation
    Authors: A Kolbinger, TJ Schäufele, H Steigerwal, J Friedel, S Pierre, G Geisslinge, K Scholich
    Embo Molecular Medicine, 2022-12-21;0(0):e16796.
    Species: Mouse
    Sample Types: Tissue Lysates
  11. Downregulation of deubiquitinating enzyme USP25 promotes the development of allergic rhinitis by enhancing TSLP signaling in the nasal epithelium
    Authors: W Chang, H Lv, L Tan, Z Gao, P Liu, D Qin, W Zhang, Y Xu
    Molecular Medicine Reports, 2022-09-30;26(5):.
    Species: Mouse, Transgenic Mouse
    Sample Types: Serum
  12. Cinnamomum cassia (L.) J.Presl Alleviates Allergic Responses in Asthmatic Mice via Suppression of MAPKs and MMP-9
    Authors: JO Lim, YH Kim, IS Lee, WI Kim, SJ Lee, SW Pak, IS Shin, T Kim
    Frontiers in Pharmacology, 2022-08-11;13(0):906916.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  13. Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation
    Authors: Y Ni, GH Wu, JJ Cai, R Zhang, Y Zheng, JQ Liu, XH Yang, X Yang, Y Shen, JM Lai, XM Ye, SJ Mo
    International journal of biological sciences, 2022-08-08;18(13):5168-5184.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  14. Experimental Schistosoma japonicum-induced pulmonary hypertension
    Authors: B Kassa, MH Lee, R Kumar, C Mickael, L Sanders, RM Tuder, M Mentink-Ka, BB Graham
    PloS Neglected Tropical Diseases, 2022-04-13;16(4):e0010343.
    Species: Mouse
    Sample Types: Tissue Homogenates
  15. Glutaminolysis is required in maintaining immune regulatory functions in B cells
    Authors: JQ Liu, XR Geng, TY Hu, LH Mo, XQ Luo, SY Qiu, DB Liu, ZG Liu, JB Shao, ZQ Liu, PC Yang
    Mucosal Immunology, 2022-01-10;0(0):.
    Species: Mouse
    Sample Types: Nasal Secretion
  16. Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis
    Authors: A Kuzumi, A Yoshizaki, KM Matsuda, H Kotani, Y Norimatsu, M Fukayama, S Ebata, T Fukasawa, A Yoshizaki-, Y Asano, K Morikawa, Y Kazoe, K Mawatari, T Kitamori, S Sato
    Nature Communications, 2021-10-12;12(1):5947.
    Species: Mouse
    Sample Types: Cell Culture Supernates, Cell Lysates, Serum, Tissue Homogenates
  17. Eosinophil extracellular traps drive asthma progression through neuro-immune signals
    Authors: Y Lu, Y Huang, J Li, J Huang, L Zhang, J Feng, J Li, Q Xia, Q Zhao, L Huang, S Jiang, S Su
    Nature Cell Biology, 2021-10-06;23(10):1060-1072.
    Species: Mouse
    Sample Types: BALF
  18. Isoalantolactone alleviates ovalbumin?induced asthmatic inflammation by reducing alternatively activated macrophage and STAT6/PPAR?gamma/KLF4 signals
    Authors: Y Song, X Li, F Liu, H Zhu, Y Shen
    Molecular Medicine Reports, 2021-08-09;24(4):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  19. Crucial role of stimulator of interferon genes-dependent signaling in house dust mite extract-induced IgE production
    Authors: H Nunokawa, Y Murakami, T Ishii, T Narita, H Ishii, H Takizawa, N Yamashita
    Scientific Reports, 2021-06-23;11(1):13157.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  20. HDAC4 induces the development of asthma by increasing Slug-upregulated CXCL12 expression through KLF5 deacetylation
    Authors: W Wei, W Chen, N He
    Journal of Translational Medicine, 2021-06-12;19(1):258.
    Species: Mouse
    Sample Types: BALF
  21. Augmenting ATG14 alleviates atherosclerosis and inhibits inflammation via promotion of autophagosome-lysosome fusion in macrophages
    Authors: H Zhang, S Ge, B Ni, K He, P Zhu, X Wu, Y Shao
    Autophagy, 2021-05-04;0(0):.
    Species: Mouse
    Sample Types: Serum
  22. WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism
    Authors: LT Wang, MH Lin, KY Liu, SS Chiou, SN Wang, CY Chai, LW Tseng, HC Chiou, HC Wang, KK Yokoyama, SH Hsu, SK Huang
    Autophagy, 2021-04-14;0(0):1-16.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  23. Microglia-derived interleukin-10 accelerates post-intracerebral hemorrhage hematoma clearance by regulating CD36
    Authors: Q Li, X Lan, X Han, F Durham, J Wan, A Weiland, RC Koehler, J Wang
    Brain, Behavior, and Immunity, 2021-02-13;94(0):437-457.
    Species: Mouse
    Sample Types: Tissue Homogenates
  24. Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1&alpha-NF-&kappaB Crosstalk In Vitro and In Vivo
    Authors: SN Chang, DK Dey, ST Oh, WH Kong, KH Cho, EM Al-Olayan, BS Hwang, SC Kang, JG Park
    International Journal of Molecular Sciences, 2020-12-04;21(23):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  25. Oral &lambda-carrageenan�intake�alleviates�skin symptoms in a hapten induced atopic dermatitis-like model
    Authors: T Iwasaki, S Watarai
    J. Vet. Med. Sci., 2020-09-17;0(0):.
    Species: Mouse
    Sample Types: Serum
  26. Prion protein signaling induces M2 macrophage polarization and protects from lethal influenza infection in mice
    Authors: J Chida, H Hara, K Uchiyama, E Takahashi, H Miyata, H Kosako, Y Tomioka, T Ito, H Horiuchi, H Matsuda, H Kido, S Sakaguchi
    PLoS Pathog., 2020-08-26;16(8):e1008823.
    Species: Mouse
    Sample Types: Tissue Homogenates
  27. De novo design of functional zwitterionic biomimetic material for immunomodulation
    Authors: B Li, Z Yuan, P Jain, HC Hung, Y He, X Lin, P McMullen, S Jiang
    Sci Adv, 2020-05-29;6(22):eaba0754.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  28. Propranolol Suppresses the T-Helper Cell Depletion-Related Immune Dysfunction in Cirrhotic Mice
    Authors: HC Tsai, CF Hsu, CC Huang, SF Huang, TH Li, YY Yang, MW Lin, TY Lee, CW Liu, YH Huang, MC Hou, HC Lin
    Cells, 2020-03-03;9(3):.
    Species: Mouse
    Sample Types: Plasma
  29. Immune responses to HIV-1 polytope vaccine candidate formulated in aqueous and alcoholic extracts of Propolis: Comparable immune responses to Alum and Freund adjuvants
    Authors: S Mojarab, D Shahbazzad, M Moghbeli, Y Eshraghi, KP Bagheri, R Rahimi, MA Savoji, M Mahdavi
    Microb. Pathog., 2019-12-16;140(0):103932.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  30. Der p2?A20 DNA vaccine attenuates allergic inflammation in mice with allergic rhinitis
    Authors: W Hu, L Ma, G Yang, X Zeng, J Liu, B Cheng, T Hu, H Zhao, Z Liu
    Mol Med Rep, 2019-10-21;0(0):.
    Species: Mouse
    Sample Types: Serum
  31. Schistosoma mansoni worm infection regulates the intestinal microbiota and susceptibility to colitis
    Authors: A Floudas, G Aviello, C Schwartz, IB Jeffery, PW O'Toole, PG Fallon
    Infect. Immun., 2019-07-23;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  32. Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
    Authors: SS Welc, I Flores, M Wehling-He, J Ramos, Y Wang, C Bertoni, JG Tidball
    Nat Commun, 2019-06-26;10(1):2788.
    Species: Mouse, Transgenic Mouse
    Sample Types: Serum
  33. Immunogenic evaluation of FMD virus immuno-dominant epitopes coupled with IL-2/FcIgG in BALB/c mice
    Authors: M Doosti, M Nassiri, K Nasiri, M Tahmooresp, S Zibaee
    Microb. Pathog., 2019-04-17;132(0):30-37.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  34. Effect of Lactobacillus rhamnosus GG immunopathologic changes in chronic mouse asthma model
    Authors: CT Wu, FH Lin, YT Lee, MS Ku, KH Lue
    J Microbiol Immunol Infect, 2019-03-23;0(0):.
    Species: Mouse
    Sample Types: BALF
  35. Effect of IL-2 co-expressed or co-inoculated with immuno-dominant epitopes from VP1 protein of FMD virus on immune responses in BALB/c mice
    Authors: M Doosti, M Nassiri, K Nasiri, M Tahmooresp, S Zibaee
    Iran J Basic Med Sci, 2019-03-01;22(3):302-309.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  36. Topical essential fatty acid oil on wounds: Local and systemic effects
    Authors: BG Lania, J Morari, AR Almeida, MND Silva, G Vieira-Dam, KA Lins, CL César, LA Velloso, NB Maia, ML Cintra, PENF Velho
    PLoS ONE, 2019-01-04;14(1):e0210059.
    Species: Mouse
    Sample Types: Serum
  37. Non-replicating Newcastle Disease Virus as an adjuvant for DNA vaccine enhances antitumor efficacy through the induction of TRAIL and granzyme B expression
    Authors: A Mohebbi, MS Ebrahimzad, S Baghban Ra, M Saeidi, A Tabarraei, SR Mohebbi, S Shirian, A Gorji, A Ghaemi
    Virus Res., 2018-12-29;261(0):72-80.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  38. Andrographolide prevented toluene diisocyanate-induced occupational asthma and aberrant airway E-cadherin distribution via p38 MAPK-dependent Nrf2 induction
    Authors: I Sulaiman, K Tan, N Mohtarrudi, JC Woei Lim, J Stanslas
    Pulm Pharmacol Ther, 2018-09-21;0(0):.
    Species: Mouse
    Sample Types: BALF
  39. Inhibition of MicroRNA-23b Attenuates Immunosuppression in Late Sepsis through NIK, TRAF1 and XIAP
    Authors: H Zhang, H Li, A Shaikh, Y Caudle, B Yao, D Yin
    J. Infect. Dis., 2018-06-20;0(0):.
    Species: Mouse
    Sample Types: Serum
  40. Effects of the Th2-dominant milieu on allergic responses in Der f 1-activated mouse basophils and mast cells
    Authors: MH Yi, HP Kim, KY Jeong, JY Kim, IY Lee, TS Yong
    Sci Rep, 2018-05-16;8(1):7706.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  41. TIM?4 blockade of KCs combined with exogenous TGF?β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts
    Authors: H Wu, X Xu, J Li, J Gong, M Li
    Int. J. Mol. Med., 2018-03-30;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  42. Carnosic acid protects mice from high-fat diet-induced NAFLD by regulating MARCKS
    Authors: HM Song, X Li, YY Liu, WP Lu, ZH Cui, L Zhou, D Yao, HM Zhang
    Int. J. Mol. Med., 2018-03-27;0(0):.
    Species: Mouse
    Sample Types: Serum
  43. Juglanin suppresses fibrosis and inflammation response caused by LPS in acute lung injury
    Authors: ZW Dong, YF Yuan
    Int. J. Mol. Med., 2018-03-09;41(6):3353-3365.
    Species: Mouse
    Sample Types: Serum
  44. The immunomodulatory effects of Zn-incorporated micro/nanostructured coating in inducing osteogenesis
    Authors: R Zhang, X Liu, Z Xiong, Q Huang, X Yang, H Yan, J Ma, Q Feng, Z Shen
    Artif Cells Nanomed Biotechnol, 2018-03-08;0(0):1-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  45. Characterization of the immune response elicited by the vaccinia virus L3 protein delivered as naked DNA
    Authors: M Ramírez, S Santos, O Martínez, R Rodríguez, E Miranda, WD Ramos-Pere, M Otero
    Vaccine, 2018-03-07;36(15):2049-2055.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  46. Immunization with Pseudomonas aeruginosa outer membrane vesicles stimulates protective immunity in mice
    Authors: X Zhang, F Yang, J Zou, W Wu, H Jing, Q Gou, H Li, J Gu, Q Zou, J Zhang
    Vaccine, 2018-02-14;36(8):1047-1054.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Capture
  47. Adaptive immune responses are altered in adult mice following neonatal hyperoxia
    Authors: VHS Kumar, H Wang, L Nielsen
    Physiol Rep, 2018-01-01;6(2):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  48. B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement
    Authors: AH Kim, JJ Chung, S Akilesh, A Koziell, S Jain, JB Hodgin, MJ Miller, TS Stappenbec, JH Miner, AS Shaw
    JCI Insight, 2017-11-02;2(21):.
    Species: Mouse
    Sample Types: Serum
  49. Glucagon-like peptide-2 improves intestinal immune function and diminishes bacterial translocation in a mouse model of parenteral nutrition
    Authors: Q Lei, J Bi, H Chen, F Tian, X Gao, N Li, X Wang
    Nutr Res, 2017-10-10;49(0):56-66.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: ELISA Capture
  50. Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function
    Authors: T Hosokawa, T Kimura, S Nada, T Okuno, D Ito, S Kang, S Nojima, K Yamashita, T Nakatani, Y Hayama, Y Kato, Y Kinehara, M Nishide, N Mikami, S Koyama, H Takamatsu, D Okuzaki, N Ohkura, S Sakaguchi, M Okada, A Kumanogoh
    J. Immunol., 2017-08-02;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. Anti-CD20 monoclonal antibody combined with adenovirus vector-mediated IL-10 regulates spleen CD4+/CD8+ T�cells and T-bet/GATA-3 expression in NOD mice
    Authors: A Tang, C Li, Z Chen, T Li
    Mol Med Rep, 2017-07-28;0(0):.
    Species: Mouse
    Sample Types: Serum
  52. Fungal immunomodulatory protein-fve could modulate airway remodel through by affect IL17 cytokine
    Authors: YT Lee, CT Wu, HL Sun, JL Ko, KH Lue
    J Microbiol Immunol Infect, 2017-06-29;0(0):.
    Species: Mouse
    Sample Types: BALF
  53. Protective Efficacy of the Trivalent Pseudomonas aeruginosa Vaccine Candidate PcrV-OprI-Hcp1 in Murine Pneumonia and Burn Models
    Authors: F Yang, J Gu, L Yang, C Gao, H Jing, Y Wang, H Zeng, Q Zou, F Lv, J Zhang
    Sci Rep, 2017-06-21;7(1):3957.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  54. Induction and characterization of anti-tumor endothelium immunity elicited by ValloVax therapeutic cancer vaccine
    Authors: SC Wagner, TE Ichim, V Bogin, WP Min, F Silva, AN Patel, S Kesari
    Oncotarget, 2017-04-25;8(17):28595-28613.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  55. Effect of a retinoid X receptor partial agonist on airway inflammation and hyperresponsiveness in a murine model of asthma
    Authors: U Fujii, N Miyahara, A Taniguchi, N Oda, D Morichika, E Murakami, H Nakayama, K Waseda, M Kataoka, H Kakuta, M Tanimoto, A Kanehiro
    Respir. Res, 2017-01-23;18(1):23.
    Species: Mouse
    Sample Types: BALF
  56. Effects of Gintonin-Enriched Fraction in an Atopic Dermatitis Animal Model: Involvement of Autotaxin Regulation
    Authors: BH Lee, HK Kim, M Jang, HJ Kim, SH Choi, SH Hwang, HC Kim, H Rhim, IH Cho, SY Nah
    Biol. Pharm. Bull., 2017-01-01;40(7):1063-1070.
    Species: Mouse
    Sample Types: Serum
  57. NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis
    Sci Rep, 2016-12-14;6(0):39075.
    Species: Mouse
    Sample Types: Tissue Homogenates
  58. Intrafibrillar silicified collagen scaffold modulates monocyte to promote cell homing, angiogenesis and bone regeneration
    Authors: Ji-Hua Chen
    Biomaterials, 2016-10-31;113(0):203-216.
    Species: Mouse
    Sample Types: Plasma
  59. Absence of the Adaptor Protein PEA-15 Is Associated with Altered Pattern of Th Cytokines Production by Activated CD4+ T Lymphocytes In Vitro, and Defective Red Blood Cell Alloimmune Response In Vivo.
    Authors: Kerbrat S, Vingert B, Junier M, Castellano F, Renault-Mihara F, Dos Reis Tavares S, Surenaud M, Noizat-Pirenne F, Boczkowski J, Guellaen G, Chneiweiss H, Le Gouvello S
    PLoS ONE, 2015-08-28;10(8):e0136885.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  60. Propionibacterium acnes Augments Antitumor, Anti-Angiogenesis and Immunomodulatory Effects of Melatonin on Breast Cancer Implanted in Mice.
    Authors: Talib W, Saleh S
    PLoS ONE, 2015-04-28;10(4):e0124384.
    Species: Mouse
    Sample Types: Serum
  61. Immunomodulator-based enhancement of anti smallpox immune responses.
    Authors: Martinez O, Miranda E, Ramirez M, Santos S, Rivera C, Vazquez L, Sanchez T, Tremblay R, Rios-Olivares E, Otero M
    PLoS ONE, 2015-04-13;10(4):e0123113.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  62. G-protein-coupled estrogen receptor agonist suppresses airway inflammation in a mouse model of asthma through IL-10.
    Authors: Itoga M, Konno Y, Moritoki Y, Saito Y, Ito W, Tamaki M, Kobayashi Y, Kayaba H, Kikuchi Y, Chihara J, Takeda M, Ueki S, Hirokawa M
    PLoS ONE, 2015-03-31;10(3):e0123210.
    Species: Mouse
    Sample Types: BALF
  63. Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-beta using BV2 microglial cells and APP/PS1 transgenic mice.
    Authors: Latta C, Sudduth T, Weekman E, Brothers H, Abner E, Popa G, Mendenhall M, Gonzalez-Oregon F, Braun K, Wilcock D
    J Neuroinflammation, 2015-03-04;12(0):41.
    Species: Mouse
    Sample Types: Protein
  64. Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase.
    Authors: Mishra, Amarjit, Brown, Alexandr, Yao, Xianglan, Yang, Shutong, Park, Sung-Jun, Liu, Chengyu, Dagur, Pradeep, McCoy, J Philip, Keeran, Karen J, Nugent, Gayle Z, Jeffries, Kenneth, Qu, Xuan, Yu, Zu-Xi, Levine, Stewart, Chung, Jay H
    Nat Commun, 2015-02-18;6(0):6224.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  65. IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells.
    Authors: Besnard A, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw T, Couper K, Ryffel B, Liew F
    PLoS Pathog, 2015-02-06;11(2):e1004607.
    Species: Mouse
    Sample Types: Serum
  66. beta-Arrestin 2 negatively regulates Toll-like receptor 4 (TLR4)-triggered inflammatory signaling via targeting p38 MAPK and interleukin 10.
    Authors: Li H, Hu D, Fan H, Zhang Y, LeSage G, Caudle Y, Stuart C, Liu Z, Yin D
    J Biol Chem, 2014-07-10;289(33):23075-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  67. Deficiency of RAMP1 attenuates antigen-induced airway hyperresponsiveness in mice.
    Authors: Li, Manyu, Wetzel-Strong, Sarah E, Hua, Xiaoyang, Tilley, Stephen, Oswald, Erin, Krummel, Matthew, Caron, Kathleen
    PLoS ONE, 2014-07-10;9(7):e102356.
    Species: Mouse
    Sample Types: BALF
  68. Improvement of spinal non-viral IL-10 gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain.
    Authors: Dengler E, Alberti L, Bowman B, Kerwin A, Wilkerson J, Moezzi D, Limanovich E, Wallace J, Milligan E
    J Neuroinflammation, 2014-05-21;11(0):92.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  69. Airway uric acid is a sensor of inhaled protease allergens and initiates type 2 immune responses in respiratory mucosa.
    Authors: Hara K, Iijima K, Elias M, Seno S, Tojima I, Kobayashi T, Kephart G, Kurabayashi M, Kita H
    J Immunol, 2014-03-24;192(9):4032-42.
    Species: Mouse
    Sample Types: BALF
  70. Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
    Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
    J Immunol, 2014-03-21;192(8):3569-81.
    Species: Mouse
    Sample Types: Tissue Homogenates
  71. Extracellular adenosine controls NKT-cell-dependent hepatitis induction.
    Authors: Subramanian M, Kini R, Madasu M, Ohta A, Nowak M, Exley M, Sitkovsky M, Ohta A
    Eur J Immunol, 2014-02-19;44(4):1119-29.
    Species: Mouse
    Sample Types: Serum
  72. Leishmania donovani targets tumor necrosis factor receptor-associated factor (TRAF) 3 for impairing TLR4-mediated host response.
    Authors: Gupta P, Giri J, Srivastav S, Chande A, Mukhopadhyaya R, Das P, Ukil A
    FASEB J, 2014-01-03;28(4):1756-68.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  73. Spironolactone attenuates bleomycin-induced pulmonary injury partially via modulating mononuclear phagocyte phenotype switching in circulating and alveolar compartments.
    Authors: Ji W, Ma Y, Zhou X, Zhang Y, Lu R, Guo Z, Sun H, Hu D, Yang G, Li Y, Wei L
    PLoS ONE, 2013-11-19;8(11):e81090.
    Species: Mouse
    Sample Types: BALF
  74. Lyn mitigates mouse airway remodeling by downregulating the TGF-beta3 isoform in house dust mite models.
    Authors: Li G, Fox J, Liu Z, Liu J, Gao G, Jin Y, Gao H, Wu M
    J Immunol, 2013-10-14;191(11):5359-70.
    Species: Mouse
    Sample Types: BALF
  75. Genetic vaccine for respiratory syncytial virus provides protection without disease potentiation.
    Authors: Johnson T, Rangel D, Graham B, Brough D, Gall J
    Mol Ther, 2013-06-10;22(1):196-205.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  76. Interleukin-33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice.
    Authors: Mizutani N, Nabe T, Yoshino S
    Immunology, 2013-06-01;139(2):205-18.
    Species: Mouse
    Sample Types: Tissue Homogenates
  77. Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
    Authors: Kim, Janice J, Bridle, Byram W, Ghia, Jean-Eri, Wang, Huaqing, Syed, Shahzad, Manocha, Marcus M, Rengasamy, Palanive, Shajib, Mohammad, Wan, Yonghong, Hedlund, Peter B, Khan, Waliul I
    J Immunol, 2013-04-03;190(9):4795-804.
    Species: Mouse
    Sample Types: Tissue Homogenates
  78. Enhanced immunogenicity of a tricomponent mannan tetanus toxoid conjugate vaccine targeted to dendritic cells via Dectin-1 by incorporating beta-glucan.
    Authors: Lipinski T, Fitieh A, St Pierre J, Ostergaard H, Bundle D, Touret N
    J Immunol, 2013-03-20;190(8):4116-28.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  79. Induction of the specific allergic immune response is independent of proteases from the fungus Alternaria alternata.
    Authors: Denis O, Vincent M, Havaux X, De Prins S, Treutens G, Huygen K
    Eur J Immunol, 2013-02-20;43(4):907-17.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  80. TLR-mediated distinct IFN-gamma/IL-10 pattern induces protective immunity against murine visceral leishmaniasis.
    Eur. J. Immunol., 2012-08-01;42(8):2087-99.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  81. The Receptor Slamf1 on the Surface of Myeloid Lineage Cells Controls Susceptibility to Infection by Trypanosoma cruzi.
    Authors: Calderon J, Maganto-Garcia E, Punzon C, Carrion J, Terhorst C, Fresno M
    PLoS Pathog., 2012-07-12;8(7):e1002799.
    Species: Mouse
    Sample Types: Serum
  82. IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs.
    Authors: Bartemes KR, Iijima K, Kobayashi T, Kephart GM, McKenzie AN, Kita H
    J. Immunol., 2011-12-23;188(3):1503-13.
    Species: Mouse
    Sample Types: BALF
  83. Monocyte-derived dendritic cell recruitment and allergic T(H)2 responses after exposure to diesel particles are CCR2 dependent.
    Authors: Provoost S, Maes T, Joos GF, Tournoy KG
    J. Allergy Clin. Immunol., 2011-09-08;129(2):483-91.
    Species: Mouse
    Sample Types: BALF
  84. The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteria.
    Authors: Ghose P, Ali AQ, Fang R, Forbes D, Ballard B, Ismail N
    J. Immunol., 2011-06-29;187(3):1333-46.
    Species: Mouse
    Sample Types: Serum
  85. IL-33-activated dendritic cells are critical for allergic airway inflammation.
    Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B
    Eur. J. Immunol., 2011-05-25;41(6):1675-86.
    Species: Mouse
    Sample Types: BALF
  86. Differential host determinants contribute to the pathogenesis of 2009 pandemic H1N1 and human H5N1 influenza A viruses in experimental mouse models.
    Authors: Otte A, Sauter M, Alleva L, Baumgarte S, Klingel K, Gabriel G
    Am. J. Pathol., 2011-05-18;179(1):230-9.
    Species: Mouse
    Sample Types: Serum
  87. Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
    Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
    Am. J. Pathol., 2011-05-10;179(1):302-14.
    Species: Mouse
    Sample Types: Tissue Homogenates
  88. Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthma.
    Authors: Hirata H, Arima M, Fukushima Y, Honda K, Sugiyama K, Tokuhisa T, Fukuda T
    Clin. Exp. Allergy, 2011-03-24;41(8):1133-42.
    Species: Mouse
    Sample Types: BALF
  89. Tumors Suppress In Situ Proliferation of Cytotoxic T Cells by Promoting Differentiation of Gr-1+ Conventional Dendritic Cells through IL-6.
    Authors: Diao J, Zhao J, Winter E
    J. Immunol., 2011-03-23;186(9):5058-67.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  90. Serotonin activates dendritic cell function in the context of gut inflammation.
    Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
    Am. J. Pathol., 2011-02-01;178(2):662-71.
    Species: Mouse
    Sample Types: Tissue Homogenates
  91. Control of mouse graft-versus-host disease following allogeneic bone marrow transplantation by blocking the CD28/B7 signaling pathway with lentiviral vector-mediated RNA interference.
    Authors: Sang W, Zhou C, Cheng N, Li Z, Zeng L, Xu K
    Immunol. Lett., 2011-01-26;136(2):194-202.
    Species: Mouse
    Sample Types: Plasma
  92. Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation.
    Authors: Wright PL, Yu J, Di YP
    J. Exp. Med., 2010-10-25;207(12):2595-607.
    Species: Mouse
    Sample Types: BALF
  93. Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages.
    Authors: Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA
    J. Immunol., 2010-07-21;185(4):2044-50.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  94. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
    Authors: Yoshizaki A, Yanaba K, Iwata Y
    J. Immunol., 2010-07-12;185(4):2502-15.
    Species: Mouse
    Sample Types: Serum
  95. Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1-/- mice.
    Authors: Niwa S, Urtz N, Baumruker T, Billich A, Bornancin F
    Lipids Health Dis, 2010-01-06;9(0):1.
    Species: Mouse
    Sample Types: Serum
  96. Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance.
    Authors: Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009-09-25;298(1):L67-78.
    Species: Mouse
    Sample Types: BALF
  97. Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice.
    Authors: Mizutani N, Nabe T, Yoshino S
    J. Immunol., 2009-08-14;183(6):4039-46.
    Species: Mouse
    Sample Types: BALF
  98. The adjuvancy of OX40 ligand (CD252) on an HIV-1 canarypox vaccine.
    Authors: Liu J, Ngai N, Stone GW, Yue FY, Ostrowski MA
    Vaccine, 2009-06-30;27(37):5077-84.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  99. A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
    Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
    J. Immunol., 2009-06-19;183(2):1291-300.
    Species: Mouse
    Sample Types: BALF
  100. Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production.
    Authors: Gueders MM, Paulissen G, Crahay C, Quesada-Calvo F, Hacha J, Van Hove C, Tournoy K, Louis R, Foidart JM, Noel A, Cataldo DD
    Inflamm. Res., 2009-06-09;58(12):845-54.
    Species: Mouse
    Sample Types: BALF
  101. Macrophage migration inhibitory factor homologs of anisakis simplex suppress Th2 response in allergic airway inflammation model via CD4+CD25+Foxp3+ T cell recruitment.
    Authors: Park SK, Cho MK, Park HK, Lee KH, Lee SJ, Choi SH, Ock MS, Jeong HJ, Lee MH, Yu HS
    J. Immunol., 2009-06-01;182(11):6907-14.
    Species: Mouse
    Sample Types: BALF
  102. Effects of a leukotriene B4 receptor antagonist on bleomycin-induced pulmonary fibrosis.
    Authors: Izumo T, Kondo M, Nagai A
    Eur. Respir. J., 2009-05-21;34(6):1444-51.
    Species: Mouse
    Sample Types: BALF
  103. Intranasal challenge with increasing ovalbumin doses differently affects airway hyperresponsiveness and inflammatory cell accumulation in mouse model of asthma.
    Authors: Bosnjak B, Ivetic Tkalcevic V, Duric K, Belamaric D, Cuzic S, Ferencic Z, Brajsa K, Glojnaric I, Antolovic R, Hrvacic B
    Inflamm. Res., 2009-05-08;58(11):773-81.
    Species: Mouse
    Sample Types: BALF
  104. Lovastatin inhibits antigen-induced airway eosinophilia without affecting the production of inflammatory mediators in mice.
    Authors: Chiba Y, Sato S, Misawa M
    Inflamm. Res., 2009-05-06;0(0):.
    Species: Mouse
    Sample Types: BALF
  105. Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model.
    Authors: Kim DY, Park JW, Jeoung D, Ro JY
    Eur. J. Pharmacol., 2009-04-05;612(1):98-105.
    Species: Mouse
    Sample Types: BALF
  106. TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity.
    Authors: Johnson TR, Rao S, Seder RA, Chen M, Graham BS
    Vaccine, 2009-04-03;27(23):3045-52.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  107. A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice.
    Authors: Shinagawa K, Ploplis VA, Castellino FJ
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009-03-13;296(5):L763-70.
    Species: Mouse
    Sample Types: BALF
  108. NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity.
    Authors: Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, Kobayashi KS, Flavell RA, Gros P, Behr MA
    J. Immunol., 2008-11-15;181(10):7157-65.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  109. Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide.
    Authors: Moon DO, Kim MO, Lee HJ, Choi YH, Park YM, Heo MS, Kim GY
    Biochem. Biophys. Res. Commun., 2008-08-13;375(2):275-9.
    Species: Mouse
    Sample Types: BALF
  110. GS143, an IkappaB ubiquitination inhibitor, inhibits allergic airway inflammation in mice.
    Authors: Hirose K, Wakashin H, Oki M, Kagami S, Suto A, Ikeda K, Watanabe N, Iwamoto I, Furuichi Y, Nakajima H
    Biochem. Biophys. Res. Commun., 2008-07-24;374(3):507-11.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  111. Lycopene suppresses ovalbumin-induced airway inflammation in a murine model of asthma.
    Authors: Lee CM, Chang JH, Moon DO, Choi YH, Choi IW, Park YM, Kim GY
    Biochem. Biophys. Res. Commun., 2008-07-16;374(2):248-52.
    Species: Mouse
    Sample Types: BALF
  112. Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis.
    Authors: Ren Y, Lu L, Guo TB, Qiu J, Yang Y, Liu A, Zhang JZ
    J. Immunol., 2008-07-15;181(2):1491-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  113. The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.
    Authors: Mabley JG, Pacher P, Murthy KG, Williams W, Southan GJ, Salzman AL, Szabo C
    J. Endocrinol., 2008-06-18;198(3):581-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  114. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
    Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
    Eur. J. Pharmacol., 2008-06-16;590(1):400-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  115. The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination against Mycobacterium tuberculosis infection by dampening IFN-gamma response.
    Authors: Palma C, Iona E, Giannoni F, Pardini M, Brunori L, Fattorini L, Del Giudice G, Cassone A
    Vaccine, 2008-06-12;26(33):4237-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  116. Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein.
    Authors: Johnson TR, Rothenberg ME, Graham BS
    J. Leukoc. Biol., 2008-06-02;84(3):748-59.
    Species: Mouse
    Sample Types: Tissue Homogenates
  117. CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in vitro expansion of viral specific CD8+ T cell memory responses from HIV-1-infected and HIV-1-uninfected individuals.
    Authors: Liu J, Yu Q, Stone GW, Yue FY, Ngai N, Jones RB, Kornbluth RS, Ostrowski MA
    Vaccine, 2008-06-02;26(32):4062-72.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  118. Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.
    Authors: Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME
    Proc. Natl. Acad. Sci. U.S.A., 2008-05-14;105(20):7240-5.
    Species: Mouse
    Sample Types: BALF
  119. Thymic stromal lymphopoietin and thymic stromal lymphopoietin-conditioned dendritic cells induce regulatory T-cell differentiation and protection of NOD mice against diabetes.
    Authors: Besin G, Gaudreau S, Menard M, Guindi C, Dupuis G, Amrani A
    Diabetes, 2008-05-13;57(8):2107-17.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  120. Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses.
    Authors: Son A, Nakamura H, Okuyama H, Oka S, Yoshihara E, Liu W, Matsuo Y, Kondo N, Masutani H, Ishii Y, Iyoda T, Inaba K, Yodoi J
    Eur. J. Immunol., 2008-05-01;38(5):1358-67.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  121. A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
    Authors: Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM
    Am. J. Pathol., 2008-04-10;172(5):1209-21.
    Species: Mouse
    Sample Types: Tissue Homogenates
  122. Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells.
    Authors: Jacobsen EA, Ochkur SI, Pero RS, Taranova AG, Protheroe CA, Colbert DC, Lee NA, Lee JJ
    J. Exp. Med., 2008-03-03;205(3):699-710.
    Species: Mouse
    Sample Types: BALF
  123. Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase.
    Authors: Iwanami K, Matsumoto I, Tanaka-Watanabe Y, Inoue A, Mihara M, Ohsugi Y, Mamura M, Goto D, Ito S, Tsutsumi A, Kishimoto T, Sumida T
    Arthritis Rheum., 2008-03-01;58(3):754-63.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  124. IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.
    Authors: Zheng T, Liu W, Oh SY, Zhu Z, Hu B, Homer RJ, Cohn L, Grusby MJ, Elias JA
    J. Immunol., 2008-01-01;180(1):522-9.
    Species: Mouse
    Sample Types: BALF
  125. Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells.
    Authors: Vanhoutte F, Paget C, Breuilh L, Fontaine J, Vendeville C, Goriely S, Ryffel B, Faveeuw C, Trottein F
    Immunol. Lett., 2007-12-17;116(1):86-94.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  126. IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.
    Authors: Yoshimoto T, Yoshimoto T, Yasuda K, Mizuguchi J, Nakanishi K
    J. Immunol., 2007-10-01;179(7):4415-23.
    Species: Mouse
    Sample Types: Serum
  127. Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function.
    Authors: Pan PY, Wang GX, Yin B, Ozao J, Ku T, Divino CM, Chen SH
    Blood, 2007-09-20;111(1):219-28.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  128. Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.
    Authors: Gaudreau S, Guindi C, Menard M, Besin G, Dupuis G, Amrani A
    J. Immunol., 2007-09-15;179(6):3638-47.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  129. Using pCIN-mIL-4 DNA vector to express mRNA and protein and to improve herpes simplex virus-induced Behcet's disease symptoms in mice.
    Authors: Lee SI, Kwon HJ, Lee ES, Yang BC, Bang D, Lee S, Sohn S
    Vaccine, 2007-08-20;25(41):7047-55.
    Species: Mouse
    Sample Types: Serum
  130. Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi.
    Authors: Medeiros MM, Peixoto JR, Oliveira AC, Cardilo-Reis L, Koatz VL, Van Kaer L, Previato JO, Mendonca-Previato L, Nobrega A, Bellio M
    J. Leukoc. Biol., 2007-05-31;82(3):488-96.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  131. Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling.
    Authors: Denis O, van den Brule S, Heymans J, Havaux X, Rochard C, Huaux F, Huygen K
    Immunology, 2007-05-16;122(2):268-78.
    Species: Mouse
    Sample Types: BALF
  132. FTY720 ameliorates oxazolone colitis in mice by directly affecting T helper type 2 functions.
    Authors: Daniel C, Sartory NA, Zahn N
    Mol. Immunol., 2007-05-01;44(13):3305-16.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  133. Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.
    Authors: Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Flaherty KR, Martinez FJ, Hogaboam CM
    Am. J. Pathol., 2007-04-01;170(4):1152-64.
    Species: Mouse
    Sample Types: Tissue Homogenates
  134. Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.
    Authors: Koya RC, Kimura T, Ribas A, Rozengurt N, Lawson GW, Faure-Kumar E, Wang HJ, Herschman H, Kasahara N, Stripecke R
    Mol. Ther., 2007-03-20;15(5):971-80.
    Species: Mouse
    Sample Types: Serum
  135. Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.
    Authors: Yamanouchi J, Rainbow D, Serra P, Howlett S, Hunter K, Garner VE, Gonzalez-Munoz A, Clark J, Veijola R, Cubbon R, Chen SL, Rosa R, Cumiskey AM, Serreze DV, Gregory S, Rogers J, Lyons PA, Healy B, Smink LJ, Todd JA, Peterson LB, Wicker LS, Santamaria P
    Nat. Genet., 2007-02-04;39(3):329-37.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  136. The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
    Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
    Life Sci., 2007-02-03;80(20):1821-31.
    Species: Mouse
    Sample Types: BALF
  137. Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis.
    Authors: Bullard DC, Hu X, Schoeb TR, Collins RG, Beaudet AL, Barnum SR
    J. Immunol., 2007-01-15;178(2):851-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  138. Prolonged inhaled allergen exposure can induce persistent tolerance.
    Authors: Van Hove CL, Maes T, Joos GF, Tournoy KG
    Am. J. Respir. Cell Mol. Biol., 2007-01-11;36(5):573-84.
    Species: Mouse
    Sample Types: BALF
  139. Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation.
    Authors: Kitamura K, Takeda K, Koya T, Miyahara N, Kodama T, Dakhama A, Takai T, Hirano A, Tanimoto M, Harada M, Gelfand EW
    J. Immunol., 2007-01-01;178(1):480-8.
    Species: Mouse
    Sample Types: BALF
  140. D-pinitol regulates Th1/Th2 balance via suppressing Th2 immune response in ovalbumin-induced asthma.
    Authors: Lee JS, Lee CM, Jeong YI, Jung ID, Kim BH, Seong EY, Kim JI, Choi IW, Chung HY, Park YM
    FEBS Lett., 2006-12-11;581(1):57-64.
    Species: Mouse
    Sample Types: BALF
  141. Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
    Authors: Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z
    J. Allergy Clin. Immunol., 2006-10-23;119(1):123-31.
    Species: Mouse
    Sample Types: BALF
  142. Roles of the small intestine for induction of toll-like receptor 4-mediated innate resistance in naturally acquired murine toxoplasmosis.
    Authors: Furuta T, Yoshikawa Y
    Int. Immunol., 2006-10-11;18(12):1655-62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  143. CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
    Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
    Int. Immunol., 2006-09-11;18(11):1531-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  144. Oral administration of an immunostimulatory DNA sequence from Bifidobacterium longum improves Th1/Th2 balance in a murine model.
    Authors: Takahashi N, Kitazawa H, Iwabuchi N, Xiao JZ, Miyaji K, Iwatsuki K, Saito T
    Biosci. Biotechnol. Biochem., 2006-08-01;70(8):2013-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  145. Allergic airway inflammation inhibits pulmonary antibacterial host defense.
    Authors: Beisswenger C, Kandler K, Hess C, Garn H, Felgentreff K, Wegmann M, Renz H, Vogelmeier C, Bals R
    J. Immunol., 2006-08-01;177(3):1833-7.
    Species: Mouse
    Sample Types: BALF
  146. CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuli.
    Authors: Tsunemi Y, Saeki H, Nakamura K, Nagakubo D, Nakayama T, Yoshie O, Kagami S, Shimazu K, Kadono T, Sugaya M, Komine M, Matsushima K, Tamaki K
    Eur. J. Immunol., 2006-08-01;36(8):2116-27.
    Species: Mouse
    Sample Types: Tissue Homogenates
  147. Prevention of murine experimental autoimmune encephalomyelitis by in vivo expression of a novel recombinant immunotoxin DT390-RANTES.
    Authors: Jia Y, Li H, Chen W, Li M, Lv M, Feng P, Hu H, Zhang L
    Gene Ther., 2006-05-18;13(18):1351-9.
    Species: Mouse
    Sample Types: Serum
  148. Short-term dietary administration of celecoxib enhances the efficacy of tumor lysate-pulsed dendritic cell vaccines in treating murine breast cancer.
    Authors: Hahn T, Alvarez I, Kobie JJ, Ramanathapuram L, Dial S, Fulton A, Besselsen D, Walker E, Akporiaye ET
    Int. J. Cancer, 2006-05-01;118(9):2220-31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  149. The differential effects of low dose and high dose concanavalin A on cytokine profile and their importance in liver injury.
    Authors: Xu X, Wei H, Dong Z, Chen Y, Tian Z
    Inflamm. Res., 2006-04-01;55(4):144-52.
    Species: Mouse
    Sample Types: Serum
  150. Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.
    Authors: Alvarez D, Swirski FK, Yang TC, Fattouh R, Croitoru K, Bramson JL, Stampfli MR, Jordana M
    J. Immunol., 2006-02-15;176(4):2568-80.
    Species: Mouse
    Sample Types: Serum
  151. Intranasal mite allergen induces allergic asthma-like responses in NC/Nga mice.
    Authors: Shibamori M, Ogino K, Kambayashi Y, Ishiyama H
    Life Sci., 2005-10-17;78(9):987-94.
    Species: Mouse
    Sample Types: BALF
  152. Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation.
    Authors: Gueders MM, Balbin M, Rocks N, Foidart JM, Gosset P, Louis R, Shapiro S, Lopez-Otin C, Noel A, Cataldo DD
    J. Immunol., 2005-08-15;175(4):2589-97.
    Species: Mouse
    Sample Types: BALF
  153. DNA vaccine encoding Der p 2 allergen generates immunologic protection in recombinant Der p 2 allergen-induced allergic airway inflammation mice model.
    Authors: Li GP, Liu ZG, Ran PX, Zhong NS
    Chin. Med. J., 2005-04-05;118(7):534-40.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  154. MyD88-dependent induction of allergic Th2 responses to intranasal antigen.
    Authors: Piggott DA, Eisenbarth SC, Xu L, Constant SL, Huleatt JW, Herrick CA, Bottomly K
    J. Clin. Invest., 2005-02-01;115(2):459-67.
    Species: Human
    Sample Types: Cell Culture Supernates
  155. Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes.
    Authors: Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF
    Comp. Immunol. Microbiol. Infect. Dis., 2004-11-01;27(6):393-411.
    Species: Mouse
    Sample Types: Serum
  156. Cytokine expression in experimental chronic otitis media with effusion in mice.
    Authors: Maeda K, Hirano T, Ichimiya I, Kurono Y, Suzuki M, Mogi G
    Laryngoscope, 2004-11-01;114(11):1967-72.
    Species: Mouse
    Sample Types: Tissue Secretion
  157. EphrinB1 is essential in T-cell-T-cell co-operation during T-cell activation.
    Authors: Yu G, Luo H, Wu Y, Wu J
    J. Biol. Chem., 2004-10-22;279(53):55531-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  158. Vbeta14(+) T cells mediate the vaccine-enhanced disease induced by immunization with respiratory syncytial virus (RSV) G glycoprotein but not with formalin-inactivated RSV.
    Authors: Johnson TR, Varga SM, Braciale TJ, Graham BS
    J. Virol., 2004-08-01;78(16):8753-60.
    Species: Mouse
    Sample Types: Tissue Homogenates
  159. Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
    Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
    J. Immunol., 2004-06-15;172(12):7408-16.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  160. Control of Leishmania major in the absence of Tyk2 kinase.
    Authors: Schleicher U, Mattner J, Blos M, Schindler H, Rollinghoff M, Karaghiosoff M, Muller M, Werner-Felmayer G, Bogdan C
    Eur. J. Immunol., 2004-02-01;34(2):519-29.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  161. A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection.
    Authors: Harandi AM, Eriksson K, Holmgren J
    J. Virol., 2003-01-01;77(2):953-62.
    Species: Mouse
    Sample Types: Serum
  162. A profibrotic function of IL-12p40 in experimental pulmonary fibrosis.
    Authors: Huaux F, 107322, Arras M, Tomasi D, Barbarin V, Delos M, Coutelier JP, Vink A, Phan SH, Renauld JC, Lison D
    Interferon-gamma modulates articular chondrocyte and osteoblast metabolism through protein kinase R-independent and dependent mechanisms, 2002-09-01;169(5):2653-61.
    Species: Mouse
    Sample Types: Tissue Homogenates
  163. Leptin accelerates autoimmune diabetes in female NOD mice.
    Authors: Matarese G, Sanna V, Lechler RI, Sarvetnick N, Fontana S, Zappacosta S, La Cava A
    Diabetes, 2002-05-01;51(5):1356-61.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  164. Anti-tumor mechanism of Z-100, an immunomodulatory Arabinomannan extracted from Mycobacterium tuberculosis strain Aoyama B, on pulmonary metastases of B16F10 melanoma: restoration of helper T cell responses via suppression of glucocorticoid-genesis.
    Authors: Oka H, Emori Y, Sasaki H, Shiraishi Y, Yoshinaga K, Kurimoto T
    Microbiol. Immunol., 2002-01-01;46(5):343-51.
    Species: Mouse
    Sample Types: Cell Culture Supernates

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Mouse IL-4 Quantikine ELISA Kit
By Anonymous on 11/28/2022
Sample Tested: Cell culture supernatant

Cell culture supernatant diluted 1:100

Mouse IL-4 Quantikine ELISA Kit M4000B
Mouse IL-4 Quantikine ELISA Kit
By Anonymous on 07/10/2020
Sample Tested: EDTA Plasma,Tissue Homogenates
Mouse IL-4 Quantikine ELISA Kit M4000B
Mouse IL-4 Quantikine ELISA Kit
By Anonymous on 08/06/2018
Sample Tested: Cell Culture Supernates
Mouse IL-4 Quantikine ELISA Kit
By Leslie Priddy on 03/30/2018
Sample Tested: Serum
Mouse IL-4 Quantikine ELISA Kit
By Rahul Kumar on 07/06/2017
Sample Tested: Mouse lung lysates

This ELISA works awesomely in mouse lung samples.

Mouse IL-4 Quantikine ELISA Kit M4000B
Mouse IL-4 Quantikine ELISA Kit
By Anonymous on 05/02/2017
Sample Tested: Lung tissue,RAW 264.7 mouse monocyte/macrophage cell line