Mouse MIS RII (NP_653130) VersaClone cDNA

Catalog #: RDC1742 Datasheet / COA / SDS

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RDC1742

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Mouse MIS RII (NP_653130) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Mouse

Product Datasheets

Product Datasheet

COA

SDS

Background: MIS RII

Müllerian inhibiting substance receptor II (MIS RII) is a type II TGF-beta superfamily receptor that forms a heteromeric complex with various type I receptors to mediate MIS signaling. Mature MIS RII has a cysteine-rich, glycosylated, extracellular domain, and a cytoplasmic region containing a serine/threonine kinase domain. Rat MIS RII shares 95% and 82% aa sequence identity with its mouse and human orthologs, respectively. Embryonically, it is expressed in mesenchymal cells surrounding the Müllerian ducts. Postnatally, it is expressed in uterine tissues and Leydig cells, showing coexpression with MIS in the testicular Sertoli and ovarian granulosa cells.

Long Name

Mullerian-Inhibiting Substance Type II Receptor

Entrez Gene IDs

269 (Human); 110542 (Mouse); 29530 (Rat)

Alternate Names

AMH type II receptor; AMHR2; AMHREC 2.7.11.30; AMHRII; C14; MIS RII; MISR2; MISRII; MISRIIMIS type II receptor; MRII; Muellerian hormone type II receptor; Muellerian hormone type-2 receptor; Mullerian hormone receptor, type II; Mullerian inhibiting substance type II receptor

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