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Mouse MS4A4B Antibody

Catalog #: MAB4504
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB4504
MAB4504-SP
Detection of MS4A4B in Mouse Thymocytes by Flow Cytometry.
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Citations (1)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse MS4A4B Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse MS4A4B. Stains mouse MS4A4B transfectants but not irrelevant transfectants.
Source
Monoclonal Rat IgG2A Clone # 444008
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
HEK293 human embryonic kidney cell line transfected with mouse MS4A4B
Met1-Val226
Accession # NP_068364
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25 µg/106 cells
See below
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of MS4A4B antibody in Mouse Thymocytes antibody by Flow Cytometry. View Larger

Detection of MS4A4B in Mouse Thymocytes by Flow Cytometry. Mouse thymocytes were stained with Rat Anti-Mouse MS4A4B Monoclonal Antibody (Catalog # MAB4504, filled histogram) or isotype control antibody (Catalog # MAB006, open histogram), followed by Allophycocyanin-conjugated Anti-Rat IgG F(ab')2Secondary Antibody (Catalog # F0113).

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: MS4A4B

MS4A4B, also called Chandra, is a member of the MS4A family of four-transmembrane proteins that includes CD20. It is expressed in immature CD4-CD8- T cells, and later in mature Th1 but not Th2 cells. MS4A4B is enriched in lipid rafts of activated T cells, and overexpression enhances Th1 cytokine expression, indicating a possible role in cell signaling. Mouse MS4A4B shares 69% overall amino acid (aa) identity with rat, and low (< 40%) aa identity with human MS4A4B.

Long Name
Membrane-spanning 4-domains, Subfamily A, Member 4B
Entrez Gene IDs
60361 (Mouse)
Alternate Names
AI463180; Chandra; Ly116; MS4A4B

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Citation for Mouse MS4A4B Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Zeb1 represses TCR signaling, promotes the proliferation of T cell progenitors and is essential for NK1.1+ T cell development
    Authors: J Zhang, M Wencker, Q Marliac, A Berton, U Hasan, R Schneider, D Laubreton, DE Cherrier, AL Mathieu, A Rey, W Jiang, J Caramel, L Genestier, A Marçais, J Marvel, Y Ghavi-Helm, T Walzer
    Cell. Mol. Immunol., 2020-05-12;0(0):.
    Species: Mouse
    Sample Types: Tissue
    Applications: Western Blot

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