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Mouse OSCAR Antibody

Catalog #: MAB1633
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB1633
MAB1633-SP
Product Details
Citations (5)
FAQs
Supplemental Products
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse OSCAR Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse OSCAR in direct ELISAs and Western blots. In Western blots, this antibody shows weak cross-reactivity with recombinant human OSCAR.
Source
Monoclonal Rat IgG2A Clone # 218311
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse OSCAR
Asp19-Asn228
Accession # Q8VBT3
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Mouse OSCAR

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: OSCAR

OSCAR is a type I transmembrane protein that is expressed specifically on osteoclast-lineage cells and regulates osteoclast differentiation.

Long Name
Osteoclast-associated Receptor
Entrez Gene IDs
126014 (Human); 232790 (Mouse)
Alternate Names
hOSCAR; MGC33613; OSCAR; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; PIGR3; PIgR-3; Poly-Ig receptor 3; Polymeric immunoglobulin receptor 3

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Citations for Mouse OSCAR Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
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  1. Fermented Sea Tangle (Laminaria japonica Aresch) Suppresses RANKL-Induced Osteoclastogenesis by Scavenging ROS in RAW 264.7 Cells.
    Authors: Jeong J W, Ji S Y et al.
    Foods
  2. Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation
    Authors: Defang Li, Jin Liu, Baosheng Guo, Chao Liang, Lei Dang, Cheng Lu et al.
    Nature Communications
  3. Ulmus macrocarpa Hance trunk bark extracts inhibit RANKL-induced osteoclast differentiation and prevent ovariectomy-induced osteoporosis in mice
    Authors: Jeong, C;Lee, CH;Lee, Y;Seo, J;Wang, W;Park, KH;Oh, E;Cho, Y;Park, C;Son, YJ;Yoon Park, JH;Kang, H;Lee, KW;
    Journal of ethnopharmacology
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  4. Osteoclastic miR-214 targets TRAF3 to contribute to osteolytic bone metastasis of breast cancer
    Authors: J Liu, D Li, L Dang, C Liang, B Guo, C Lu, X He, HY Cheung, B He, B Liu, F Li, J Lu, L Wang, AB Shaikh, F Jiang, C Lu, S Peng, Z Zhang, BT Zhang, X Pan, L Xiao, A Lu, G Zhang
    Sci Rep, 2017-01-10;7(0):40487.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Binding Assay
  5. Pathological role of osteoclast costimulation in arthritis-induced bone loss.
    Authors: Ochi S, Shinohara M, Sato K, Gober HJ, Koga T, Kodama T, Takai T, Miyasaka N, Takayanagi H
    Proc. Natl. Acad. Sci. U.S.A., 2007-06-25;104(27):11394-9.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot

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