Mouse Reg3A Antibody

Catalog # Availability Size / Price Qty
AF3907
AF3907-SP
Product Details
Citations (1)
FAQs
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Mouse Reg3A Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse Reg3A in direct ELISAs and Western blots. In these formats, less than 1% cross-reactivity with recombinant human Reg1B and recombinant mouse Reg1 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant mouse Reg3A (R&D Systems, Catalog # 3907-RG)
Glu27-Gln175
Accession # O09037
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse Reg3A (Catalog # 3907-RG)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Reg3A

Regenerating islet-derived protein III alpha (Reg3A), also named Pancreatitis Associated-Protein 2 (PAP-2), is a secreted, 17 kDa member of the Reg family. These C-type lectin superfamily proteins are involved in various biological functions, including liver and pancreatic regeneration and proliferation. Reg3A is predominately expressed in intestine and exocrine pancreas. It is also induced in primary liver tumors but is not expressed in normal liver. Mature mouse Reg3A contains 149 amino acid residues and shares less than 60% aa sequence identity with other Reg3 proteins. The protein sequence of mouse Reg3A is 87% and 61% identical to that of rat and human Reg3A, respectively.

Long Name
Regenerating Islet-derived IIIa
Entrez Gene IDs
5068 (Human); 19694 (Mouse); 171162 (Rat)
Alternate Names
hepatocarcinoma-intestine-pancreas; HIPpancreatitis-associated protein; Human proislet peptide; Lithostathine 3; pancreatic beta cell growth factor; Pancreatitis-associated protein 1; PAP homologous protein; PAP1FLJ18565; PAP2; PAPPAP-H; PBCGF; proliferation-inducing protein 34; proliferation-inducing protein 42; Reg III-alpha; REG3; Reg3A; REG-3-alpha; regenerating islet-derived 3 alpha; regenerating islet-derived protein 3-alpha; Regenerating islet-derived protein III-alpha; REG-III

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Citation for Mouse Reg3A Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Autophagy in pancreatic acinar cells in caerulein-treated mice: immunolocalization of related proteins and their potential as markers of pancreatitis.
    Authors: Zhang L, Zhang J, Shea K, Xu L, Tobin G, Knapton A, Sharron S, Rouse R
    Toxicol Pathol, 2013-05-02;42(2):435-57.

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