Home / Serpin C1/Antithrombin-III / Mouse Serpin C1/Antithrombin-III Antibody

Mouse Serpin C1/Antithrombin-III Antibody

Catalog #: MAB1287
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB1287
MAB1287-SP
Product Details
Citations (5)
FAQs
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Serpin C1/Antithrombin-III Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse Serpin C1/Antithrombin-III in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant human (rh) Serpin C1 is observed and no cross-reactivity with rhSerpin A1, A3, F2, recombinant mouse Serpin D1 or A5 is observed.
Source
Monoclonal Rat IgG2A Clone # 208730
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Serpin C1/Antithrombin-III
His33-Asn465
Accession # P32261
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Mouse Serpin C1/Antithrombin-III

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Serpin C1/Antithrombin-III

Serpin C1, also called Antithrombin-III, is the principal plasma serpin that inhibits blood clotting proteases such as thrombin and factor Xa.

Entrez Gene IDs
462 (Human); 11905 (Mouse)
Alternate Names
Antithrombin-III; AT3antithrombin-III; ATIII; ATIIIantithrombin III; MGC22579; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serine-cysteine proteinase inhibitor clade C member 1; Serpin C1; serpin peptidase inhibitor, clade C (antithrombin), member 1

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Citations for Mouse Serpin C1/Antithrombin-III Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
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  1. Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD
    Authors: Higgins NR, Greenslade JE, Wu JJ et al.
    Brain pathology (Zurich, Switzerland)
  2. Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates
    Authors: R Karlsson, P Chopra, A Joshi, Z Yang, SY Vakhrushev, TM Clausen, CD Painter, GP Szekeres, YH Chen, DR Sandoval, L Hansen, JD Esko, K Pagel, DP Dyer, JE Turnbull, H Clausen, GJ Boons, RL Miller
    Science Advances, 2021-12-22;7(52):eabl6026.
    Species: Hamster
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. Single-domain antibodies targeting antithrombin reduce bleeding in hemophilic mice with or without inhibitors
    Authors: E Barbon, G Ayme, A Mohamadi, JF Ottavi, C Kawecki, C Casari, S Verhenne, S Marmier, L van Witten, S Charles, F Collaud, CV Denis, OD Christophe, F Mingozzi, PJ Lenting
    EMBO Mol Med, 2020-03-11;0(0):e11298.
    Species: Human
    Sample Types: Cell Culture Lysates
    Applications: Western Blot
  4. Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide.
    Authors: Dower K, Ellis DK, Saraf K, Jelinsky SA, Lin LL
    J. Immunol., 2008-03-01;180(5):3520-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Functional Assay
  5. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
    Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
    J. Exp. Med., 2004-11-22;200(11):1419-26.
    Species: Human
    Sample Types: Cell Culture Supernates, Whole Cells
    Applications: Functional Assay, Western Blot

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